Improving clinical success
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The success of the clinical use of sequencing based tests (from single gene to genomes) depends on the accuracy and consistency of variant interpretation. Aiming to improve the interpretation process through practice guidelines, the American College of Medical Genetics and Genomics (ACMG) and the Association for Molecular Pathology (AMP) have published standards and guidelines for the interpretation of sequence variants.
9p vioraclene 31-03-2024 6 2 Download
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Understanding the mechanistic effects of novel immunotherapy agents is critical to improving their successful clinical translation. These effects need to be studied in preclinical models that maintain the heterogenous tumor microenvironment (TME) and dysfunctional cell states found in a patient’s tumor.
25p vicwell 29-02-2024 4 2 Download
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Seizure frequency and seizure freedom are among the most important outcome measures for patients with epilepsy. In this study, we aimed to automatically extract this clinical information from unstructured text in clinical notes. If successful, this could improve clinical decision-making in epilepsy patients and allow for rapid, large-scale retrospective research.
9p vighostrider 25-05-2023 4 2 Download
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Clinical Information System (CIS) usage can reduce healthcare costs over time, improve the quality of medical care and safety, and enhance clinical efficiency. However, CIS implementation in developing countries poses additional, different challenges from the developed countries.
14p vighostrider 25-05-2023 3 2 Download
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One of the greatest success of pediatric hematology is a prominent improvement of survival in acute lymphoblastic leukemia (ALL). Therefore, special attention needs to be paid to long-term side effects of the treatment such as neurotoxicity.
13p vianrose2711 27-04-2021 13 1 Download
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Asthma and obesity are public health problems with increasing prevalence worldwide. Clinical and epidemiologic studies have demonstrated that obese asthmatics have worse clinical control and health related quality of life (HRQL) despite an optimized medical treatment. Bariatric surgery is successful to weight-loss and improves asthma control; however, the benefits of nonsurgical interventions remain unknown.
11p vimontana2711 05-04-2021 13 2 Download
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Infection with Burkholderia cepacia complex (Bcc) results in a heterogeneous clinical course ranging from asymptomatic colonization of the airways to fulminant respiratory failure in patients with cystic fibrosis (CF). Early eradication of Pseudomonas aeruginosa improves clinical outcomes.
5p vimaine2711 26-03-2021 7 1 Download
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Research investigating prognosis in musculoskeletal pain conditions has only been moderately successful in predicting which patients are unlikely to recover. Clinical decision making could potentially be improved by combining information taken at baseline and re-consultation.
11p vitennessee2711 02-02-2021 7 2 Download
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Meniscal allograft transplantation (MAT) may improve symptoms and function, and may limit premature knee degeneration in patients with symptomatic meniscal loss. The aim of this retrospective study was to examine patient outcomes after MAT and to explore the different potential definitions of ‘success’ and ‘failure’.
9p vipalau2711 30-12-2020 3 0 Download
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Nevus of Ota is a facial congenital pigmentation disorder affecting mainly the face. Nowadays, different types of pigmentation lasers have been used to treat Nevus of Ota. Very few research to address the treatment results have been performed in Vietnam. Objective: To evaluate the clinical efficacy of Qs Alexandrite lasers in treatment of Nevus of Ota in Vietnamese people. Method: 35 patients with Nevus of Ota were treated by 8 sessions of Qs Alexandrite laser 755 nm at monthly intervals. Clinical improvement was evaluated based on color of the Nevus of Ota before, during and after treatment.
9p trinhthamhodang9 10-12-2020 9 2 Download
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Newborn screening (NBS) occupies a unique space at the intersection of translational science and public health. As the only truly population-based public health program in the United States, NBS offers the promise of making the successes of translational medicine available to every infant with a rare disorder that is difficult to diagnose clinically, but for which strong evidence indicates that presymptomatic treatment will substantially improve outcomes.
13p virome2711 13-01-2020 10 0 Download
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The aim of the study was to review and evaluate the current use of videoconference education for nurses in KwaZulu-Natal. Methodology: A review the literature on VC education in nursing using bibliometric review strategies was conducted and two nurses’ education courses conducted via videoconferencing was evaluated against a set of criteria developed and validated by the Department of TeleHealth at the University. Results: 81 publications addressing videoconference nurse education were found, most being published after 2000.
15p quenchua1 06-11-2019 16 0 Download
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Clinical simulations are designed to increase communication and experience among all members of the healthcare team in a low stakes environment. In this study we investigate the current application of in-situ simulation for training and educational purposes at the University of Virginia Health System. One factor we examined includes the impact of the level of fidelity of the simulator on clinician experience. We also looked at the ability to document the situation and if generational differences exist among participants that determine their engagement.
12p kequaidan1 05-11-2019 24 0 Download
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Lupus nephritis comprises a spectrum of glomerular, vascular, and tubulointerstitial lesions, which has significant racial variations in severity and manifestations. The current International Society of Nephrology/Renal Pathology Society classification (2003) has been successfully improved for the categorization of lupus glomerulonephritis.
6p vixyliton2711 17-04-2019 21 1 Download
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(bq) part 1 book “basics of psychotherapy - a practical guide to improving clinical success” has contents: what is this book about, what is psychotherapy, what is the psychotherapy relationship, what is an initial evaluation.
157p tieu_vu15 07-09-2018 42 3 Download
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(bq) part 2 book “basics of psychotherapy - a practical guide to improving clinical success” has contents: what is a formulation, what is a treatment plan, what is communication, what is collaboration, what is an autodidact, what is the sum and substance, suggested readings.
177p tieu_vu15 07-09-2018 32 2 Download
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We successfully built capacity of a team of public sector health care workers to provide integrated coaching in both clinical skills and QI across a province. The PCT is a feasible and effective model to spread and sustain quality activities and improve HIV care services in a decentralized rural setting.
9p thaodien102 06-11-2015 46 2 Download
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A key barrier to the use of plant-derived materials is the high cost of developing the market, even when unique new products have been created. As in many emerging product markets, research in new products begins in small companies that are under-capitalized and lack the resources needed to go beyond the laboratory scale. The success rate for commercialization is low and promising products often languish through lack of volume generation.
44p loixinloi 08-05-2013 51 2 Download
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There is an urgent need to improve the health of women and children, particularly in areas of Africa, where Millennium Development Goals (MDGs) 4 and 5 are most lagging. This requires strong community engagement and formal investments in national health systems, especially for those least likely to be reached through current national health strategies, such as those in rural communities. Community Health Workers (CHWs) have been internationally recognized for their notable success in reducing morbidity and averting mortality in mothers, newborns and children.
104p nhamnhiqa 01-03-2013 52 2 Download
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New technologies, developments in implant design and advances in surgical technique have improved outcomes after joint replacement and decreased rate of complications. It is not a surprise that the number of arthroplasties increases steadily every year and nowadays more than one million patients undergo the procedure annually worldwide. This book is a sequel of a successful series dedicated to one of the fastest growing fields in orthopedics - arthroplasty.
350p japet75 25-02-2013 46 3 Download