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In vitro evaluation of
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PPOS (Progestin-Primed Ovarian Stimulation) has shown efficacy in preventing early luteinization and improving outcomes in infertile women. However, data among those with poor ovarian response (POR) are limited. This study aimed to evaluate the effect of PPOS protocol on the chance of success throughout the IVF process in patients with POR (POSEIDON group III & IV) undergoing IVF/ICSI in Vietnam.
11p
vikoch
27-06-2024
3
1
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Circulating tumor cell (CTC) clusters play a critical role in carcinoma metastasis. However, the rarity of CTC clusters and the limitations of capture techniques have retarded the research progress. In vitro CTC clusters model can help to further understand the biological properties of CTC clusters and their clinical significance.
17p
vishanshan
27-06-2024
1
1
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The need for intelligent and effective treatment of diseases and the increase in drug design costs have raised drug repurposing as one of the effective strategies in biomedicine. There are various computational methods for drug repurposing, one of which is using transcription signatures, especially single-cell RNA sequencing (scRNAseq) data, which show us a clear and comprehensive view of the inside of the cell to compare the state of disease and health.
11p
vishanshan
27-06-2024
1
1
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CD13 (APN) is an Alanyl-Aminopeptidase with diverse functions. The role of CD13 for gliomas is still unknown. In this study, data of glioma patients obtained by TCGA and CGGA databases were used to evaluate the survival rate and prognostic value of CD13 expression level. Protein expression of CD13 was confirmed by immunofluorescence staining of fresh patient tissues.
15p
vishanshan
27-06-2024
1
1
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Cancer is the most destructive and fatal disease, representing an urgent medical challenge to the world. The discovery of a new anticancer candidate may help reduce or eliminate this alarming disease to a greater extent. On similar lines, in silico research was carried out on novel naphthylidene isoxazolidinedione derivatives that were logically conceived, synthesized, purified, and structurally characterized. In vitro biological evaluation revealed the most active compound 4d with an inhibitory concentration of 42.87 μM against K562 and 47.42 μM on A549 cells.
10p
dianmotminh02
03-05-2024
3
1
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The melting points of the complexes were >350oC, indicating high thermal stability. Cu-Zn-containing complex showed the least binding energy against the three proteins. The bioactivity scores of the complexes were between -0.50 and 0.0. Against A549 Cu-Zn, Co-Zn and Fe-Zn containing complexes showed potential activity. Against MCF-7, Fe-Cu containing complex had IC50 of 53.5 whereas Co-Zn containing complex was active against HepG2. Three complexes were active against S. aureus in the tested range.
18p
dianmotminh02
03-05-2024
2
1
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. In vitro biological evaluation revealed the most active compound 4d with an inhibitory concentration of 42.87 μM against K562 and 47.42 μM on A549 cells. The anticancer activity of this naphthylidene isoxazolidinedione derivative was evident by cell cycle and apoptosis assays, which showed arrest of the G2/M phase (65.6%) of the K562 cells and induction of apoptosis with 21.47% apoptotic cells as compared to 0.2% of untreated cells, respectively.
10p
dianmotminh02
03-05-2024
2
2
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A large number of studies have demonstrated the wound-healing effects of LLLT in vitro, in animal models, and in clinical practice. However, there are also differences in the study results, which are dose and wavelength dependent of LLLT. Objective: Evaluation of the wound healing process in experimental animals treated with low- level laser therapy in clinical and histopathology.
8p
vioraclene
31-03-2024
12
2
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Part 2 book "Applied veterinary andrology and frozen semen technology" includes content: Gross evaluation of semen; microscopic test for evaluation of semen; sperm morphology; in vitro fertility tests; assessment of metabolic activity of semen; miscellaneous tests for evaluation of semen quality; estimation of bacterial load in semen samples;... and other contents.
129p
muasambanhan05
22-01-2024
5
2
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The aim of the present study was to evaluate the effect of foetal calf serum (FCS) on the production of bovine embryo in vitro. We conducted two experiments: (1) to evaluate the effect of FCS on the production of bovine embryo in vitro and (2) to evaluate the effect of duration of FCS supplementation on the production of bovine embryo in vitro.
5p
vimichaelfaraday
28-12-2023
3
2
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Ebook "Retinal gene therapy: Methods and protocols" describes a spectrum of methods and protocols that can be used for the bench-to-bedside development and evaluation of retinal gene therapy. Methods for the successful delivery of these gene therapy vector systems to the retina are examined, as well as assays to test the efficacy in vitro in cell cultures, for gene augmentation and gene editing in vivo on rodents, pigs, and monkey retinas, and on human retinal explants as well as in human clinical studies.
373p
lucchinguyen
28-12-2023
9
2
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Anti-inflammatory is the property of a substance or treatment that reduces inflammation in the body (redness, swelling, and pain) by blocking certain substances in the body that cause inflammation. They are used to treat many different conditions.
5p
vimichaelfaraday
28-12-2023
4
3
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The flowers of Hylocereus undatus (Haw.) Britton & Rose have been reported in vitro antioxidant and tyrosinase inhibitory activities. This study screened preliminarily the triterpenoid constituents and evaluated in vitro tyrosinase inhibitory activity of H. undatus flowers. H. undatus flowers were harvested from Binh Thuan Province, Vietnam at four different flowering stages, and their five separated parts (stamen, pistil, petals, ovary, and sepals) were extracted with ethanol.
7p
vikissinger
21-12-2023
3
1
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The aim of this study is to evaluate an AAV vector that can selectively target breast cancer cells and to investigate its specificity and anti-tumor effects on breast cancer cells both in vitro and in vivo, offering a new therapeutic approach for the treatment of EpCAM-positive breast cancer.
9p
vileonardodavinci
23-12-2023
3
2
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CAD/CAM restorations of deep cavities are the challenges faced by intraoral-scanner (IOS) for accurate 3D data acquisition. This study aimed to evaluate the influence of cavity depth on the accuracy of intraoral digital impressions.
8p
vikissinger
21-12-2023
3
2
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The study aimed to determine the influence of A. brasilense at different doses on the production of disease-free potato seed minitubers grown on coco-peat substrates, using hydroponic solutions and isolated under greenhouse conditions at Dalat, Vietnam.
6p
vispacex
16-11-2023
4
2
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The dissolution and the release kinetics of the active ingredient of the reference tablet Tylenol 8 Hour 650 mg were surveyed in order to formulate the paracetamol 650mg prolonged release tablet and there was an in vitro equivalent evaluation between the prepared paracetamol 650mg prolonged release tablet and the reference tablet Tylenol 8 Hour 650 mg.
9p
vispacex
16-11-2023
5
2
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To evaluate in vitro antiurolithiatic activity of Terminalia catappa leaves in Vietnam, through inhibition of calcium oxalate formation. In addition, moisture value, preliminary screening of the chemical composition and determination of tanninoid content of aqueous extract also were conducted.
7p
vispacex
16-11-2023
7
2
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The aim of this study was to evaluate VITROS(®) syphilis Treponema pallidum agglutination (VITROS(®) syphilis TPA) assay based on enhanced chemiluminescence principle for detection of syphilis infection in blood donors.
6p
vispacex
13-11-2023
6
2
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Glomerular filtration rate (GFR) is an important indicator of renal function. Several methods have been applied to calculate GFR in clinical exams. In this study, we evaluated and compared between radionuclide plasma sampling methods (double blood samples, in vitro methods) and in vivo Gate’s method using 99mTc-diethylene triamine penta-acetic acid (99mTc-DTPA) renography.
5p
vispacex
13-11-2023
12
2
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