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Inadequate response
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Currently, there is no approved guideline regarding management of patients with polycythemia vera (PCV) undergoing percutaneous coronary intervention (PCI) given the low prevalence. Standard maintenance therapy may be inadequate in cases where patients’ response to standard treatment show heterogeneity.
4p
viintuit
26-09-2023
3
0
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Inadequate response to corneal laser refractive surgery, e.g., ectatic corneal diseases, may not be identified by conventional examinations, hence creating therapeutic uncertainty. Herein we demonstrate the application of genetic prescreening to augment preassessment for corneal laser refractive surgery and highlight the ability to prevent the possibility of enrolling a subject at risk for developing ectatic corneal diseases.
8p
vigamora
23-05-2023
6
3
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Biologic drugs are expensive treatments used in rheumatoid arthritis (RA). Switching among them is common practice in patients who have had an inadequate response or intolerable adverse events. The National Institute of Health and Clinical Excellence (NICE) UK, which aims to curtail postcode prescribing, has provided guidance on the sequential prescription of these drugs.
8p
viannito2711
20-04-2021
7
1
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The treat-to-target (T2T) approach to the care of patients with rheumatoid arthritis involves using validated metrics to measure disease activity, frequent follow-up visits for patients with moderate to high disease activity, and escalation of therapy when patients have inadequate therapeutic response as assessed by standard disease activity scores.
7p
viannito2711
20-04-2021
14
2
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This meta-analysis was conducted to determine the efficacy, safety and tolerability of tofacitinib in the treatment of rheumatoid arthritis in patients with an inadequate response or intolerance to at least one of the nonbiologic or biologic disease-modifying antirheumatic drugs (DMARDs).
11p
viannito2711
20-04-2021
12
1
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Ethic education for students is a part of the comprehensive education process and responsibility of the whole society where education at school plays a leading role. The actual situation of ethic education in universities and colleges is inadequate, even though school leaders and lecturers clearly understand the meaning and important role of ethic education for students.
9p
tamynhan9
02-12-2020
5
1
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Despite advances in the gene-set enrichment analysis methods; inadequate definitions of gene-sets cause a major limitation in the discovery of novel biological processes from the transcriptomic datasets. Typically, gene-sets are obtained from publicly available pathway databases, which contain generalized definitions frequently derived by manual curation.
13p
viflorida2711
30-10-2020
9
3
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Lung cancer is the leading cause of cancer deaths worldwide. Surgery, radiotherapy at conventional and high dose and chemotherapy are the mainstay for lung cancer treatment. Insufficient migration and activation of tumour specific effector T cells seem to be important reasons for inadequate host anti-tumour immune response.
8p
vimoscow2711
29-08-2020
8
0
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Linseed and mustard are the most important prehistoric crops in the world, usually cultivated as major rabi oilseeds in India. The major constraints for low productivity are inadequate supply of nutrients and poor production practices. Technological demonstrations on linseed and mustard were conducted at 58 locations covering 24.4 ha area in participatory mode using improved linseed cultivar JLS 9, JLS 23 and mustard (pusa mahak) during 2007-08 to 2011-12.
12p
angicungduoc6
22-07-2020
15
1
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Neoadjuvant chemoradiotherapy is regarded as the standard of treatment for locally advanced lower rectal cancer, although some of these cases are systemic, and distant control may be inadequate. Neoadjuvant chemotherapy could compensate for such shortcomings, potentially yielding better survival outcomes.
9p
vikuala271
13-06-2020
6
2
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The occurrence of micronutrient deficiencies in crops has increased markedly in recent years due to intensive cropping, soil erosion, leaching, liming of acid soils, reduced use of manures, increased purity of chemical fertilizers and use of marginal lands for crop production. Among the micronutrients, the boron plays an important role in flowering and fertilization process and hence boosting yield and quality of crop produce.
7p
quenchua4
06-04-2020
15
0
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Preterm neonates undergo many painful procedures as part of their standard care in the neonatal intensive care unit. However, pain treatment is inadequate in many of these routine procedures.
7p
videshiki2711
21-02-2020
14
2
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Iron plays an important role in body defense and essential for normal immune system development where its deficiency may result in an inadequate immune response. We aimed to assess the lymphocyte subsets in childhood iron deficiency anemia (IDA) with their laboratory correlations.
6p
vidr2711
19-02-2020
17
0
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The decline in the rice crop responses to applied fertilizer nutrients, inter alia, could be ascribed to emerging nutrient deficiencies on account of modern era of agriculture and inadequate or imbalanced application of fertilizers. It has become increasingly recognized around the world that N, P and K fertilizers alone are not always sufficient to provide balanced nutrition for optimal rice yields and quality, therefore, application of secondary and micronutrient elements has to be made.
23p
nguaconbaynhay3
07-02-2020
18
2
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: Stimulation is the most common intervention during neonatal resuscitation at birth, but scarce information is available on the actual methods, timing and efficacy of this basic step. To evaluate the occurrence, patterns and response to tactile stimulation at birth in a low-resource setting.
7p
vidublin2711
13-01-2020
10
0
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Attention-deficit/hyperactivity disorder (ADHD) has become a major aspect of the work of child and adolescent psychiatrists and paediatricians in the UK. In Scotland, Child and Adolescent Mental Health Services were required to address an increase in referral rates and changes in evidence-based medicine and guidelines without additional funding.
14p
vimoskva2711
30-12-2019
5
0
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This paper considers the analysis of concept maps utilized as a learning tool in disciplines dealing with immunological responses in two undergraduate Health programs. In total, 48 concept maps were assessed regarding their propositions and structure. The clarity of the propositions was analyzed by using the Propositional Clarity Table and they were classified as adequate propositions (AP) and inadequate propositions (IP). In 48 concept maps, 648 propositions were analyzed in order to determine semantic clarity and conceptual mistakes.
13p
kequaidan1
05-11-2019
15
1
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The study however, identified inadequate number of Agriculture Extension Agents, insufficient finances as well as logistics and equipment as the main challenges faced by the District Departments of Agriculture in climate change response in the region. The study recommends that the District Departments of Agriculture in the various Metropolitan, Municipal and District Assemblies should be adequately resourced by the central government to undertake their core functions.
8p
jcript
23-05-2019
28
0
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All are expected to observe the highest standards of research integrity and to embed good practice in all aspects of their work, including the training of new researchers.They must operate honestly and openly in respect of their own actions and in response to the actions of others involved in research. 1 The spectrum of inappropriate behaviour is wide, ranging from minor misdemeanours which may happen occasionally and inadvertently, to significant acts of misappropriation or fabrication.
12p
docvachiase
03-05-2013
47
2
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In the paper-based General Test, the topics in the analytical writing section will be presented in the test book and you will handwrite your essay responses on the answer sheets provided. Make sure you use the correct answer sheet for each task. It is important to budget your time. Within the 45-minute time limit for the Issue task, you will need to allow sufficient time to choose one of the two topics, think about the issue you’ve chosen, plan a response, and compose your essay.
0p
thamgiacongdong
02-05-2013
46
5
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