Insufficient coverage

Whole-genome bisulfite sequencing (WGBS) has become the standard method for interrogating plant methylomes at base resolution. However, deep WGBS measurements remain cost prohibitive for large, complex genomes and for population-level studies. As a result, most published plant methylomes are sequenced far below saturation, with a large proportion of cytosines having either missing data or insufficient coverage.

14p vibeauty 23-10-2021 11 1   Download

Sequencing studies of exonic regions aim to identify rare variants contributing to complex traits. With high coverage and large sample size, these studies tend to apply simple variant calling algorithms. However, coverage is often heterogeneous; sites with insufficient coverage may benefit from sophisticated calling algorithms used in low-coverage sequencing studies.

10p vikentucky2711 26-11-2020 9 1   Download

When analyzing health coverage of children, it is critical to focus not solely on insurance coverage status, but also on the quality of coverage and actual access to care the child is experiencing. CHF estimates that approximately 16.9 million of insured children are experiencing barriers to accessing care, meaning that even though they technically have insurance coverage, covered benefits may be insufficient, out-of-pocket costs for families may be unaffordable, there may not be appropriate medical providers in their area, or they may not have access to transportation to get to care.

20p seketnoi 28-04-2013 29 3   Download

Acknowledging this situation, in the latter half of the 1990s Bolivia gave priority to programmes to resolve the social situation. Efforts were made to achieve a better level of coverage in education, health and basic sanitation services, with positive but still insufficient results. As regards health, in 2001 the maternal mortality rate in Bolivia was 420 per 100,000 live births, the highest rate in Latin America. The infant mortality rate fell from 89 per 1,000 live births in 1990 to 54 per 1,000 live births in 2004. Between 1994 and 2003, the proportion of births attended...

75p doiroimavanchuadc 19-02-2013 47 4   Download

Although health economics provides a useful starting point for such analyses of coverage, the ultimate effect of a mandate is not easily reduced to, and in fact could differ from, the predicted effect of treating penalty amounts as dollar-for-dollar equivalents to subsidies. People can respond to penalties and subsidies differently and in ways that are not considered in standard health economics models.

80p quaivatxanh 01-12-2012 48 7   Download