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Integration site analysis
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Extension of prostate cancer beyond the primary site by local invasion or nodal metastasis is associated with poor prognosis. Despite significant research on tumour evolution in prostate cancer metastasis, the emergence and evolution of cancer clones at this early stage of expansion and spread are poorly understood.
18p
vicwell
29-02-2024
2
1
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Ebook "Mound centers and seed security: A comparative analysis of botanical assemblages from middle woodland sites in the lower illinois valley" integrates an interpretation of these two historical trends. Unlike most journal articles on related subjects, the volume includes a lengthy review of literature on both Hopewell studies and Middle Woodland agriculture, making it a useful resource for researchers starting out in either field.
74p
manmanthanhla0201
26-02-2024
2
1
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To detect the HPV genotype and integration sites in patients with high-risk HPV infection at different stages of photodynamic therapy using nanopore technology and to evaluate the treatment effect.
12p
vialfrednobel
23-12-2023
6
3
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The simulation for this purpose will be done using PVSyst V7.0 to estimate the production of the photovoltaic system installation on the building’s rooftop by using the weather data imported from MeteoNorm. Analysis of simulation results confirms the potential of on-site PV system exploitation to provide energy for data center - which is a critical infrastructure in urban area.
4p
vistephenhawking
26-04-2022
9
3
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We investigated rupture geometry, size, and slip distribution of October 30, 2020, Samos (Sisam)–Kuşadası earthquake combining seismographs, GPS measurements, and SAR analysis. Right after the earthquake, we measured 13 additional campaignbased GPS sites to intensify the available GPS network consisting of 10 continuous stations. We combined all available seismographs to have the best possible accuracy for mainshock and aftershock hypocenter locations. We compiled all available seismic profiles and integrated them using high-resolution bathymetry to map seismically active faults.
11p
tanmocphong
29-01-2022
13
1
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The integration of a viral genome into the host genome has a major impact on the trajectory of the infected cell. Integration location and variation within the associated viral genome can influence both clonal expansion and persistence of infected cells.
24p
viarchimedes
26-01-2022
12
0
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Based on the input gene sets, Lisa first uses histone mark ChIP-seq and chromatin accessibility profiles to construct a chromatin model related to the regulation of these genes. Using TR ChIP-seq peaks or imputed TR binding sites, Lisa probes the chromatin models using in silico deletion to find the most relevant TRs.
14p
viarchimedes
26-01-2022
4
0
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Protein phosphorylation plays an important role in lactation. Differentially modified phosphorylation sites and phosphorylated proteins between peak lactation (PL, 90 days postpartum) and late lactation (LL, 280 days postpartum) were investigated using an integrated approach, namely, liquid chromatography with tandem mass spectrometry (LC-MS/MS) and tandem mass tag (TMT) labeling, to determine the molecular changes in the mammary tissues during the different stages of goat lactation.
11p
vitzuyu2711
29-09-2021
11
1
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Malonylation is a recently discovered post-translational modification that is associated with a variety of diseases such as Type 2 Diabetes Mellitus and different types of cancers. Compared with experimental identification of malonylation sites, computational method is a time-effective process with comparatively low costs.
10p
vijeeni2711
30-06-2021
7
1
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Analyzing the integration profile of retroviral vectors is a vital step in determining their potential genotoxic effects and developing safer vectors for therapeutic use. Identifying retroviral vector integration sites is also important for retroviral mutagenesis screens.
5p
vikentucky2711
24-11-2020
9
1
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The analysis of viral vector genomic integration sites is an important component in assessing the safety and efficiency of patient treatment using gene therapy. Alongside this clinical application, integration site identification is a key step in the genetic mapping of viral elements in mutagenesis screens that aim to elucidate gene function.
9p
viflorida2711
30-10-2020
9
2
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Bioinformatics tools designed to identify lentiviral or retroviral vector insertion sites in the genome of host cells are used to address the safety and long-term efficacy of hematopoietic stem cell gene therapy applications and to study the clonal dynamics of hematopoietic reconstitution.
12p
viconnecticut2711
29-10-2020
15
2
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Numerous studies have highlighted that long non-coding RNAs (lncRNAs) can bind to microRNA (miRNA) sites as competing endogenous RNAs (ceRNAs), thereby affecting and regulating the expression of mRNAs and target genes.
10p
vikuala271
13-06-2020
13
0
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The important physico-chemical parameters of water such as temperature, pH, dissolved oxygen, free carbon dioxide, total alkalinity, total dissolved solids, electrical conductivity, Biological oxygen demand, nitrate-nitrogen, ammonia-nitrogen, phosphate-phosphorous and soil quality parameters such as pH and organic carbon were studied in Nalban wetland in triplicate by standard methods.
12p
kethamoi2
15-12-2019
23
0
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The quality of river water is influenced by two factors: nature and man. The aims of this paper are to determine the influence of anthropogenic sources of pollution on water quality, by assessing integrated measurements from use of the Pollution Index (PI) of Indonesia and diverse statistical techniques, including one-way analysis of variance (ANOVA) and ArcGIS.
7p
caygaocaolon1
13-11-2019
39
2
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The purpose of reservoir characterisation is to fi gure out the spatial distribution of petrophysical properties such as porosity, permeability and water saturation that are key parameters for construction of the geological model. Characterisation of a carbonate reservoir is often diffi cult mainly due to the complexity of its pore system. This study presents an integrated approach to using well log and micro-geological data to characterise rock fabrics and their pore system for a carbonate reservoir in the HR structure.
8p
quenchua
27-09-2019
34
0
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The study was carried out with 1168 individuals from the sites of Puna de Jujuy, San Pedro de Atacama, Calama, Pisagua and 29 craniometric variables. Discriminant Analysis methods were used for the evaluation of differences between sites and sexes and the reclassification of individuals in another site than the original one.
18p
guestgreat
16-05-2019
24
0
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This paper presents a work of mining informal social media data to provide insights into students’ learning experiences. Analyzing such kind of data is a challenging task because of the data volume, the complexity and diversity of languages used in these social sites. In this study, we developed a framework which integrating both qualitative analysis and different data mining techniques in order to understand students’ learning experiences.
10p
jangni
13-04-2018
35
1
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The development of a 796 acre off shore site to provide 200 Mega watts of electricity from a vertical wind farm powered by twenty magnetically levitated 10 Mega Watt Vertical Axis Wind Turbines (VAWT). The project site’s 796 acre area can accommodate a total of up to (100) 10 Mw wind turbines. See Appendix for additional proposed wind classification 4 to 5 project sites. Phase one will begin with an off shore site feasibility study of the proposed site to provide the best wind condition information & geographic aspect analysis to achieve optimal performance.
34p
loixinloi
08-05-2013
51
1
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BAP31 is a 28-kDa integral membrane protein of the endoplasmic reticulumwhose cytosolicdomaincontains two caspase recognition sites that are preferentially cleaved by initiator caspases,such as caspase-8. Recently,we reported that the caspase-resistant BAP31 inhibited Fas-mediated apoptotic membrane fragmentation and the release of cytochromec from mitochondria in KB epithelial cells (Nguyen M.,Breckenridge G.,Ducret A &Shore G. (2000) Mol. Cell.Biol.20,6731–6740).
8p
tumor12
20-04-2013
32
3
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