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Interactions between cells
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Evidence from observational studies suggests an association between chronic obstructive pulmonary disease (COPD) and lung cancer. The potential interactions between the immune system and the lungs may play a causative role in COPD and lung cancer and offer therapeutic prospects.
9p
vishanshan
27-06-2024
1
1
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The development of drug resistance is a major cause of cancer therapy failures. To inhibit drug resistance, multiple drugs are often treated together as a combinatorial therapy. In particular, synergistic drug combinations, which kill cancer cells at a lower concentration, guarantee a better prognosis and fewer side effects in cancer patients.
16p
vikoch
27-06-2024
3
1
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T cell immunoglobulin and mucin-domain containing-3 (TIM-3) is a cell surface molecule that was first discovered on T cells. However, recent studies revealed that it is also highly expressed in acute myeloid leukemia (AML) cells and it is related to AML progression. As, Glutamine appears to play a prominent role in malignant tumor progression, especially in their myeloid group, therefore, in this study we aimed to evaluate the relation between TIM-3/Galectin-9 axis and glutamine metabolism in two types of AML cell lines, HL-60 and THP-1.
15p
vikoch
27-06-2024
4
1
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Targeted drugs are the main methods of RCC treatment. However, drug resistance is common in RCC patients, in-depth study of the drug-resistant mechanism is essential. Methods We constructed sunitinib resistant and Twist overexpressed A498 cells, and studied its mechanisms in vitro and in vivo.
14p
vikoch
27-06-2024
1
1
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Ebook "Study of the peptide–peptide and peptide–protein interactions and their applications in cell imaging and nanoparticle surface modification" focuses on the study of interactions between protein and peptides and their potential applications in cell imaging and nanoparticle surface modification. Drawing inspiration from naturally occurring coiled-coil binding pairs, it proposes a novel covalent peptide tag and probe system, based on the concept of “affinity guided covalent conjugation.
103p
tracanhphuonghoa1007
22-04-2024
3
3
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Acute myeloid leukemia (AML), caused by the abnormal proliferation of immature myeloid cells in the blood or bone marrow, is one of the most common hematologic malignancies. Currently, the interactions between malignant myeloid cells and the immune microenvironment, especially T cells and B cells, remain poorly characterized.
11p
vibransone
28-03-2024
4
2
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Ebook "Plants and heavy metals" focuses on the many aspects of the interaction between plants and heavy metals. Not only it describes the effects of heavy metal toxicity on the plant cell and its organs but it also examines the mechanisms that plants adopt to scavenge heavy metals at cellular, physiological, and metabolic level. Plants and Heavy Metals also analyses Hyperaccumulator plants and shows their potential role in phytoremediation technologies in light of the recent research results.
96p
coduathanh1122
27-03-2024
4
1
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Genetic suppression occurs when the deleterious effects of a primary “query” mutation, such as a disease-causing mutation, are rescued by a suppressor mutation elsewhere in the genome. Methods To capture existing knowledge on suppression relationships between human genes, we examined 2,400 published papers for potential interactions identified through either genetic modification of cultured human cells or through association studies in patients.
19p
vicwell
29-02-2024
4
1
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Ebook "Glycoscience and microbial adhesion (Topics in current chemistry, Volume 288)" explains all PIA-related principles of medical device-associated infections. It is our hope, that this collection of expert articles, ranging from structural ch- istry and structural biology to biochemistry and medicine, will be a stimulation and motivation for our colleagues in the life sciences.
194p
manmanthanhla0201
26-02-2024
1
1
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Ebook "Muscle biophysics: From molecules to cells" gathers studies performed by scientists who have used diverse muscle techniques, and who have shaped the field of muscle contraction throughout the past years. Some of these studies are, in fact, intrinsically associated with early studies looking at the mechanisms underlying the Fenn effect and load dependence of force production, the relation between force and filament overlap, and the nature of cross-bridge rotation.
360p
tachieuhoa
28-01-2024
11
2
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Ebook "Biocommunication of plants" process and evaluate information and then modify their behaviour accordingly. These highly diverse competences are made possible by parallel sign(alling)-mediated communication processes within the plant body (intraorganismic), between the same, related and different species (interorganismic), and between plants and non-plant organisms (transorganismic). Intraorganismic communication involves sign-mediated interactions within cells (intracellular) and between cells (intercellular).
388p
tachieuhoa
28-01-2024
9
2
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Ebook "B cell receptor signaling: Methods and protocols" looks the current advanced protocols used to study aspects of the B cell receptor (BCR). The chapters in this book cover topics such as the mutant of BCR repertoire to understand antibody evolution; interactions between B cells and viruses; mechanical force during BCR activation; B cell signaling using flow cytometry; confocal microscopy, total internal reflection microscopy and intravital two-photon microscopy;...
262p
lucchinguyen
28-12-2023
5
2
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MicroRNA (miR)-214-3p is emerging as an important tumor suppressor in esophageal cancer. In this study, we examined the interaction between miR-214-3p and RAB14, a membrane trafficking protein shown to exert oncogenic functions in other malignancies, in esophageal cancer cells.
14p
vileonardodavinci
23-12-2023
5
2
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Single nucleotide polymorphisms (SNPs) located in microRNA (miRNA) binding sites can affect the interactions between miRNAs and target genes, which is related to cancer susceptibility and tumorigenesis. However, the association between SNPs located in miR-17-92 cluster binding sites and ESCC risk remains unclear.
12p
vileonardodavinci
23-12-2023
3
3
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Recapitulating the tumor microenvironment (TME) in vitro remains a major hurdle in cancer research. In recent years, there have been significant strides in this area, particularly with the emergence of 3D spheroids as a model system for drug screening and therapeutics development for solid tumors. However, incorporating macrophages into these spheroid cultures poses specific challenges due to the intricate interactions between macrophages and cancer cells.
17p
vileonardodavinci
23-12-2023
4
2
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The present study was to investigate the differential effects of either miR-200a-3p or YAP on tumorous cells’ fate in vitro in HPV-negative and HPV-positive cervical cancer cell models, and to explore if the changes in proliferation, migration, and invasion of the CC cells with different HPV statuses could be attributed to the differential interactions between miR-200a-3p and YAP.
12p
vialfrednobel
23-12-2023
5
3
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Radio/chemotherapy and immune systems provide examples of hormesis, as tumours can be stimulated (or reduced) at low radio/chemical or antibody doses but inhibited (or stimulated) by high doses. Methods Interactions between effector cells, tumour cells and cytokines with pulsed radio/chemo-immunotherapy were modelled using a pulse differential system.
14p
vialfrednobel
23-12-2023
7
3
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Part 1 book "Updates on brucellosis" includes content: Risk factors for brucella Spp. in domestic and wild animals, brucellosis at the wildlife livestock human interface, the interaction between brucella and the host cell in phagocytosis, brucella induced thrombocytopenia and bleeding, ocular manifestations of brucellosis, neurobrucellosis, brucellosis – granulomatous spine infection.
111p
oursky09
08-11-2023
4
2
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Interactions between the programmed cell death receptor 1 (PD-1) and its ligand (PD-L1) lead to immune evasion in various tumors and are associated with poor prognosis in patients with pancreatic cancer; however, the roles of PD-L1-containing exosomes in pancreatic cancer is poorly understood.
10p
vischultz
20-10-2023
1
1
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In the tumor microenvironment (TME), the dynamic interaction between tumor cells and immune cells plays a critical role in predicting the prognosis of colorectal cancer. This study introduces a novel approach based on artificial intelligence (AI) and immunohistochemistry (IHC)-stained whole-slide images (WSIs) of colorectal cancer (CRC) patients to quantitatively assess the spatial associations between tumor cells and immune cells.
10p
vioracle
29-09-2023
6
4
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