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Invasive fungal infections
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Ebook "Vaccines for invasive fungal infections: Methods and protocols" includes cutting-edge techniques for the study of invasive mycosis vaccine creation and implementation; provides step-by-step detail essential for reproducible results; contains key implementation advice from the experts;...
352p
lucchinguyen
28-12-2023
3
2
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Fusarium species are saprophytic fungi with a worldwide distribution. These fungi cause various infections among immunocompromised patients; however, they can also involve immunocompetent individuals.
6p
vigamora
23-05-2023
5
3
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Invasive pulmonary Aspergillus and invasive bronchial aspergillosis is a life-threatening opportunistic fungal infection that predominantly affects immunocompromised hosts. In addition, since the patient was supported with venovenous extracorporeal membrane oxygenation, we were able to perform safe bronchoscopic debridement of airway lesions and intratracheal instillation of liposomal amphotericin B.
6p
videadpool
05-05-2023
6
2
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The main mechanism of resistance in A. fumigatus involves incorporation of tandem repeats in the promoter region of cyp51A, along with point mutations in the gene sequence. Resistant isolates tend to arise either due to excessive use of azole fungicides in the agricultural fields, from where they reach human through sporulation; or by prolonged treatment of patients with azole drugs. The early diagnosis of aspergillosis is very crucial for successful treatment of a patient.
8p
mudbound
10-12-2021
6
1
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Pneumocystis jirovecii pneumonia (PCP)-related risk factors among patients with solid tumors are not completely defined. Thus, we aimed to characterize PCP cases with underlying solid tumors, to highlight the factors contributing to its development besides the prolonged use of moderate-to-high dose corticosteroids.
9p
vimahuateng
26-11-2021
10
2
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Pulmonary mucormycosis caused by Mucorales is a highly lethal invasive fungal infection usually found in immunocompromised patients. Isolated pulmonary mucormycosis in immunocompetent patients is very rare. Here, we present a case of a 32-year-old male who developed pulmonary mucormycosis without any known immunodeficiency.
8p
vijichoo2711
31-05-2021
15
1
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Triazole, polyene, and echinocandin antifungal agents are extensively used to treat invasive fungal infections (IFIs); however, the optimal prophylaxis option is not clear. This study aimed to determine the optimal agent against IFIs for patients with hematological malignancies.
17p
vianrose2711
27-04-2021
14
1
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Advanced chronic obstructive pulmonary disease (COPD) often leads to hospitalisation and invasive aspergillosis (IA) is a serious complication. Aspergillus sensitisation may worsen symptoms in COPD.
10p
vimichigan2711
26-03-2021
13
2
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Pneumocystis pneumonia (PCP) is an important cause of acute respiratory failure (ARF) in immunocompromised patients, yet no actual clinical tool suitably identifies patients at risk. Recently, a multivariable prediction model has been proposed for haematology patients with ARF requiring intensive care unit (ICU) admission to assess the risk of PCP (PCP score). However, it has not yet been validated externally.
9p
vimichigan2711
26-03-2021
12
2
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Mucormycosis is an uncommon but life-threatening invasive fungal infection, mostly occurs in immunocompromised patients. Lacking the appropriate antifungal drugs is one of the reasons that lead to difficulties in the management of mucormycosis. Curcuma longa has been used traditionally and widely to treat various diseases, including fungal infections.
10p
tamynhan5
10-12-2020
7
2
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Veno-occlusive disease, Graft-versus-Host disease, invasive or localized bacterial, viral and fungal infections are known as adverse events after hematopoietic stem cell transplantation representing the major cause for morbidity and mortality.
11p
viamsterdam
18-09-2020
13
0
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Fungal infections or mycoses are classified as Superficial, Subcutaneous, and Systemic depending on the degree of invasion of the host. Superficial fungal infections are most common in tropical and subtropical countries. Superficial fungal infections of the skin are one of the most common dermatological conditions seen in clinical practice. It affects 20- 25% of the population. In this study, 1473 Suspected superficial fungal infection cases were identified among approximately 3500 patients screened during August 2017 to August 2019.
7p
trinhthamhodang1212
06-04-2020
27
0
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The frequency of fungal infections in tuberculosis patients has increased in recent years. A study published in the Bulletin of the World Health Organization estimates that more than a million people develop chronic pulmonary aspergillosis after being treated for TB every year. As bronchoalveolar lavage (BAL) fluid samples are generally useful specimens in the diagnosis of invasive pulmonary aspergillosis (IPA), this study was designed to evaluate the incidence of fungal infections in pulmonary tuberculosis patients by direct microscopy and culture of BAL samples.
7p
caygaocaolon3
09-03-2020
20
0
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There have been many studies supporting fluconazole prophylaxis in preterm infants for prevention of invasive fungal infections (IFIs). However, the routine use of fluconazole prophylaxis in neonatal intensive care units (NICUs) raises concerns with respect to resistance development, including the selection of resistant Candida species.
9p
vichengna2711
25-02-2020
17
0
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Human fungal infections are on the rise. Fungi causing skin infections are common but invasive fungi which are less known appear pathogenic and deadly. Environment, immunity and individual risk factors contribute for its susceptibility. Some of them can be fatal, if not diagnosed early and treated. Advances in molecular techniques help in early diagnosis. New modality of treatment such as antifungal peptides, fungal vaccines are in the pipeline. Improper and “Over the counter” medication must be avoided for the complete cure.
4p
chauchaungayxua3
07-02-2020
13
0
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Invasive aspergillosis has increased considerably in recent years; this serious infection was primarily described in severely immunocompromised patients and patients with moderate levels of immune suppression. We conducted this study on 85 patients admitted to the chest department and chest ICU with severe exacerbations of chronic lung diseases in the period from April 2018 to April 2019. We collected tracheal aspirates BAL fluid and blood samples for isolation of Aspergillus spp. by convectional culture and assay of galactomannan level in these samples using ELISA. Aspergillus spp.
12p
chauchaungayxua3
07-02-2020
15
0
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The present investigation was aimed to understand early infection process and plant pathogen interactions involved in tolerance and susceptibility in groundnut challenged with Sclerotium rolfsii by Scanning Electron Microscopy (SEM). The histo-pathological changes were recorded at different time intervals in two groundnut genotypes with differential reaction to stem rot disease viz., Cv: “ICGV 86590” (resistant) and Cv: “Narayani” (susceptible). These genotypes were grown in glass house and challenged with stem rot pathogen.
8p
nguathienthan2
19-12-2019
18
0
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To study the various fungi causing otomycosis with its isolation and identification of species from the clinical laboratory of Vijayanagara Institute of Medical Sciences, Ballari, ear swab samples are collected from the department of ENT which is suspected for fungal cause of otomycosis. KOH mount was done for the presence of fungal elements and also Grams staining of the sample is done to look for uniformly stained Gram positive fungal elements. Another ear swab from the same ear is directly streaked on the SDA slant for fungal culture.
4p
kethamoi2
15-12-2019
8
1
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The eye may be infected from external sources or through intraocular invasion of microorganisms carried by the blood stream. The common eye infections caused by bacterial and fungal pathogens are blepharitis, conjunctivitis, internal and external hordeolum, keratitis, dacryocystitis. Timely institution of appropriate therapy must be initiated to control the infections and thereby minimize the ocular morbidity.
9p
cothumenhmong1
08-12-2019
8
0
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Keratomycosis is an invasive fungal infection of the cornea which usually occurs following corneal trauma by vegetative material. It is usually caused by hyaline fungus such as Aspergillus, Fusarium and Acremonium, but rare case reports with phaeoid fungus have been reported. We report here a case of keratomycosis caused by Exserohilum rostratum. E. rostratum is a dematiaceous fungus that has been known to cause sinusitis and subcutaneous infections but it has rarely been reported to be a cause of keratomycosis.
3p
cothumenhmong1
08-12-2019
9
0
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