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Investigational agent
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This paper responds to the recently published article by Wang et al. and will expand the discourse regarding management of localized MCC. Specifically, we will discuss the surgical excision approaches; alternative treatment options for MCC including radiotherapy, Mohs micrographic surgery and novel immunotherapy agents being investigated through several clinical trials.
3p
vikoch
27-06-2024
2
1
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In this study, the gold nanoparticles (AuNPs) were synthesized via redox reaction, by using ethylene diamine tetra-acetic acid (EDTA) as a protecting and reducing agent, with tetrachloroauric acid (HAuCl4) as precursor and seed solution. The ultraviolet-visible spectroscopy (UV-Vis) method was utilized to investigated the reaction conditions (the EDTA:HAuCl4 ratio, the amount of seed solution and stirring solution time) at room temperature. The synthesized AuNPs were deposited on the surface of fluorine doped tin oxide (FTO) by electrophoresis deposition.
8p
dianmotminh02
03-05-2024
6
1
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The plasmon characterization of AgNS on paper was systematically investigated by the diffuse reflectance spectroscopy. The fabricated paper-based SERS substrates were used to detect melamine in an aqueous solution and to determine the influence of type RAs on the enhancement factor (EF) and signal uniformity of SERS substrates. Among the four types of RAs, the SERS substrates used NaBH4 have the highest SERS signal with the limit of detection of 10-8 M for melamine and the EF = 2.3 × 109 .
9p
dianmotminh02
03-05-2024
4
1
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In this study, achira (Canna edulis) starch was oxidized by sodium hypochlorite and the effects of different concentration of oxidation agent (1, 2, 3 and 5%) on the physicochemical properties, morphological properties and crystallinity of achira starch (AS) was investigated. The carbonyl and carboxyl content, starch colour parameters, swelling capacity, solubility, IR spectra, SEM and XRD of native and oxidized achira starch (OAS) were evaluated.
7p
dianmotminh02
03-05-2024
1
1
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The genetic origins of chemotherapy resistance are well established; however, the role of epigenetics in drug resistance is less well understood. To investigate mechanisms of drug resistance, we performed systematic genetic, epigenetic, and transcriptomic analyses of an alkylating agent-sensitive murine lymphoma cell line and a series of resistant lines derived by drug dose escalation.
11p
vioraclene
31-03-2024
2
1
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Ebook "Portable chemical sensors: Weapons against bioterrorism" is to focus on research related to the rapid detection of agents and weapons of bioterrorism and provide a comprehensive review of the research topics most pertinent to advancing devices applicable to the rapid real-time detection of toxicants such as microbes, pathogens, toxins, or nerve gases.
350p
coduathanh1122
27-03-2024
2
1
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Ebook "Vanadium: Biochemical and molecular biological approaches" is particularly timely as it exactly coincides with the centennial anniversary of the discovery of vanadium by Professor Henze, in the blood cells of an ascidian (tunicate) collected in Gulf of Naples in 1911. Vanadium, atomic number 23, covers a wide range of oxidation states (from -2 to +5) and has unpaired electrons. Depending on these properties, a wide variety of enzymes and compounds containing vanadium have been found and the biochemical behaviour of vanadium has been investigated extensively.
235p
coduathanh1122
27-03-2024
4
1
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Ebook "Programmed cell death in cancer progression and therapy (Advances in experimental medicine and biology, Volume 615)" give a comprehensive overview of the mechanisms that are involved in mediating and regulating PCD in cancer. We also provide a detailed indication of the utility of PCD in cancer therapy. This book will be a valuable resource for researchers investigating the role of PCD in cancer and other diseases, researchers investigating the molecular mechanism of chemotherapeutic agents and drug-resistance in cancer and for physicians using chemotherapeutic agents.
362p
duongthandue0501
28-02-2024
1
1
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Ebook "Viruses in foods (Food microbiology and food safety series)" is the first book that comprehensively discusses the role of viruses in foodborne disease outbreaks, along with strategies for the prevention and control of viral contamination of food. Cases of viral foodborne outbreaks are on the rise in part due to the increases in population, scarcity of clean water, and changes in eating habits.
355p
manmanthanhla0201
27-02-2024
2
1
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The objective of this study was to investigate the tolerance of capecitabine, an example of oral chemotherapy, among older adults with cancer and explore factors associated with capecitabine-related side effects and treatment changes, to enhance supportive care.
14p
vialfrednobel
23-12-2023
5
4
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Part 1 book "Disease in wild animals, investigation and management" includes content: Disease and epizootiology—basic principles, special problems in working with free-living animals, identifying and defining a disease, collecting population data, defining environmental factors, formulating and testing hypotheses, investigation of disease outbreaks and chronic or inapparent disease, records and recordkeeping, disease management—general principles, management of the causative agent/factor or its vector.
219p
oursky10
04-12-2023
4
3
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Part 2 book "Veterinary clinical epidemiology - From patient to population" includes content: Design and evaluation of clinical trials, statistical significance, medical ecology and outbreak investigation, measuring and expressing occurrence, establishing cause, source and transmission of disease agents, the cost of disease.
116p
oursky09
08-11-2023
7
3
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Role of antiangiogenic agents in first-line treatment for advanced NSCLC in the era of immunotherapy
“Anti-angiogenetic drugs plus chemotherapy” (anti-angio-chemo) and “immune checkpoint inhibitors plus chemotherapy” (ICI-chemo) are superior to traditional chemotherapy in the first-line treatment of patients with advanced non-small-cell lung cancer (NSCLC). This study aimed to investigate the role of antiangio‑ genic agents for advanced NSCLC in the era of immunotherapy.
22p
vischultz
20-10-2023
4
1
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Metastatic castration-resistant prostate cancer (mCRPC) remains a therapeutic challenge and evidence for late-line treatments in real-life is limited. The present study investigates the efficacy and safety of an oral metronomic chemo-hormonal regimen including cyclophosphamide, etoposide, estramustine, ketoconazole and prednisolone (KEES) administered in a consecutive biweekly schedule.
10p
vischultz
20-10-2023
5
2
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The study on the induction of plant defense against to anthracnose disease of chili by sodium nitroprusside solution was investigated during pre- and post-harvest. Pre-harvest treatment was conducted by spraying the chili plants with sodium nitroprusside (SNP, nitric oxide donor) solution at 0 (control), 0.05 and 0.1 mM every 3 days for 9 times before inoculating with the spore suspension of Colletotrichum gloeosporioides (the causal agent of anthracnose disease) and then sprayed with SNP again 1 time after inoculating.
8p
viisac
23-09-2023
5
1
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Trichophyton rubrum is a causative agent responsible for human chronic dermatophytosis worlwide. It is a common causative agent of the dermatophyte infections and resistant to many antifungal drugs. Oxidative damaging agents belong to a strong antimicrobial group and have been intensively investigated.
8p
vimulcahy
18-09-2023
3
3
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This study aimed to quantify the phenolic contents and the antioxidant capacities of leaf extract powders from three Myrtaceae plants, namely Cleistocalyx operculatus (Vietnamese name: Vối), Psidium guajava (Ổi), and Rhodomyrtus tomentosa (Sim), investigate their inhibitive activities on the growth of bacteria isolated from spoiled shrimps, and evaluate their values as preservative agents in the cold storage of Pacific whiteleg shrimps (Penaeus vannamei).
15p
viengels
25-08-2023
7
2
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This research has been initiated to examine the effectiveness of DCBRN-01VN lotion in degrading some readily available organic phosphorous (OP). UPLC-MS/MS technique was used to measures the amount of residual pesticide via selected ion monitoring. The results showed that lotion effectively degrades OP expediently.
12p
viengels
25-08-2023
8
3
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The purpose of this study is to investigate the factors influencing the financial literacy of adults in Vietnam. The Binary Logistic regressions were taken for dependent variables and independent variables derived from 692 respondents from 63 provinces in Vietnam; The regressions results show that “major in finance” and financial socialization agents have significantly positive impact on adult financial literacy.
13p
viberkshire
09-08-2023
5
4
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The physico-chemical properties of electrospun polyvinyl alcohol (PVA) based hydrogel composites were investigated. Tetraethyl orthosilicate (TEOS) was employed as a crosslinking agent. 2.5-7.5 wt% of gallic acid was successfully loaded into an electrospun poly vinyl alcohol fiber.
6p
viberbers
09-08-2023
4
3
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