Keratoconjunctivitis sicca

Sjogren’s syndrome, an autoimmune disease of the exocrine glands, results in keratoconjunctivitis sicca, xerostomia, and dental caries. It is often overlooked, considered by clinicians to be a benign disease. However, it can cause life-threatening extra-glandular complications that affect multiple organ systems.

6p vigamora 23-05-2023 7 2   Download

The study was conducted on 67 client-owned dogs affected with Keratoconjunctivitis Sicca (KCS) to evaluate the expression of Caspase-3 and Interferon gamma in conjunctival cells. After complete ophthalmic examinations cases were staged into Early (E), Late (L) and ulcer group (R). Conjunctival scrapings for immunocytochemical expression of Caspase-3 and INF gamma and tissue samples for histopathological confirmation of KCS were collected from early KCS, late KCS and apparently healthy animals.

10p chauchaungayxua10 18-03-2021 13 1   Download

The study was conducted to evaluate the effect of tacrolimus 0.1% ointment on the tear fluid cytokines during treatment of keratoconjunctivitis sicca in dogs. Total 35 pug dogs were screened and graded as normal, early and late KCS cases on the basis of schirmer tear test. The concentration of the IFN-γ and immunohistochemistry (IHC) expression of MMP-9 were higher in KCS cases compared to normal cases.

10p trinhthamhodang9 16-12-2020 8 2   Download