Latex beads

High-sensitivity C-reactive protein (hsCRP) is an important marker of inflammation to predict the risk of CVDs. Existing reagent system for the detection of hs CRP has its limitation such as higher cost and requirement of sophisticated instruments, which minimize the utility of this effective marker utility in Indian population. The study was aimed to formulate and validate an improved reagent system for the detection of hs CRP. The study was targeted to formulate a latex-enhanced reagent format by selecting inert microscopic latex particles.

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Other methods have proposed the use of standard beads (Polysciences latex beads), as well described by Gasol and del Giorgio in 2000. Briefly, the beads have to be counted every day and must be sonicated to avoid aggregation. Flow rate calibration can be performed by weighing a tube containing water, processing various volumes, estimating the time needed for each volume to go through and then reweighing the tube. This makes it possible to calculate the mean of the flow rate per minute (Paul, 2001).

354p yeutinh98 22-09-2012 49 6   Download