Lethality time

Despite therapeutic advances, once a cancer has metastasized to the bone, it represents a highly mor‑ bid and lethal disease. One third of patients with advanced clear cell renal cell carcinoma (ccRCC) present with bone metastasis at the time of diagnosis.

21p vicwell 29-02-2024 4 2   Download

The incidence of hypervirulent epidemic Clostridium difficile has increased around the world and now in Australia. Assays that are capable of rapidly identifying these strains would enable earlier diagnosis and timely infection control response. The aims of the first part of the study were to validate and develop a molecular technique for the rapid diagnosis of toxigenic C.

134p runthenight07 01-03-2023 6 2   Download

To determine the hypnotic and analgesic effects of brimonidine, and evaluate its efficacy and safety for general anesthesia. Potentiation of pentobarbital sleeping time following brimonidine administration was observed in mice, as was the analgesic activity of brimonidine.

12p vidietmarhopp 28-12-2021 7 0   Download

Glioblastoma (GBM) is the most malignant primary brain tumor in adults, with a median survival time of one and a half years. Traditional treatments, including radiation, chemotherapy, and surgery, are not curative, making it imperative to find more effective treatments for this lethal disease.

9p vialabama2711 21-09-2020 11 0   Download

The acute toxicity of zinc, copper and lead to the marine invertebrate Idotea baltica (Crustacea, Isopoda) was evaluated by static bioassays, calculating the LT50 (lethality time for 50%) for males and females. Survival time decreased with increasing concentrations of zinc, copper and lead. Zinc was more toxic to Idotea than copper and lead. Lead was the least toxic of the metals tested.

8p vitamix 19-02-2019 15 0   Download

Efficacy of a baculovirus as a biological control agent is evaluated according to biological parameters, median lethal dose (LD50) of the virus, and median lethal time (LT50) of infected larvae.

5p vivant2711 01-02-2019 32 1   Download

Chondrosarcoma is a common form of bone cancer which affects the fibrous connective tissue around a joint. It most commonly develops in legs, arms, shoulder blades, rib cage, and pelvis. Capsaicin is an active bitter compound found in red pepper, the fruit of the species Capsicum annuum, and it has been shown to have a lethal effect on different types of cancer.

13p nutifooddau 27-01-2019 21 3   Download

Automatic sprinklers are highly effective elements of total system designs for fire protection in buildings. They save lives and property, producing large reductions in the number of deaths per thousand fires, in average direct property damage per fire, and especially in the likelihood of a fire with large loss of life or large property loss. When sprinklers are present in the fire area, they operate in 93% of all reported structure fires large enough to activate sprinklers, excluding buildings under construction.

113p dacotaikhoan 25-04-2013 44 6   Download

Point of view shots allow us to experience the emotions of the lead character, her anxiety and apprehension as she goes to meet the imprisoned serial killer, Hannibal Lecter, for the first time. Director Jonathan Demme discusses this scene and the influence of Alfred Hitchcock on the Silence of the Lambs in his interview with Mark Cousins as part of the BBC’s Face to Face series. This scene is also an example of how the continuity style employs over-the shoulder dialogue. In the classic continuity scene, the dialogue begins with a two-shot of the participants in the scene. The editing.

21p khanhchilam 01-04-2013 40 6   Download

The strategic communications audit should result in more than just an identification of areas or practices that need to be improved. To maximize the chances that audit findings will be used and actual practice improved as a result, the audit should: Demonstrate through data how communications problems are causing problems in the present (as opposed to speculating about their future impact). At the same time, the audit should reinforce practices that are current organizational strengths.

5p doipassword 01-02-2013 37 2   Download

As the Baby Boomers begin to retire, their many trillions of dollars of savings and investments are shifting from accumulation to decumulation, making the ideas and techniques described in Lifetime Financial Advice timely and necessary. We hope and expect that researchers will continue to follow this path in the future by placing a much greater emphasis on life-cycle finance than in the past. We intend that upcoming Research Foundation monographs will reflect the heightened emphasis on life-cycle finance.

30p mebachano 01-02-2013 36 3   Download

The Minamata poisoning episode provided local researchers with the hard evidence that first linked mercury discharges to its bioaccumulation in the environment. Cats in Minamata were the first to show signs of mercury poisoning, although at the time the unusual behaviour exhibited by the cats was unexplained. The disease was known locally as “dancing cat disease” in reference to the uncontrollable muscle spasms and tremors seen in the poisoned cats.

80p saimatkhauroi 01-02-2013 56 6   Download

Funding conditions at European banks improved following special policy measures introduced by central banks around the beginning of December. Before that time, many banks had been unable to raise unsecured funds in bond markets and the cost of short-term funding had risen to levels only previously exceeded during the 2008 banking crisis. Dollar funding had become especially expensive. The ECB then announced that it would lend euros to banks for three years against a wider set of collateral.

11p machuavo 19-01-2013 42 2   Download

We are in trouble. The health of our country is being compromised due to a lifestyle of overeating and sedentary habits. Never before in our history has the health of so many individuals been put at risk due to the lethal combination of an inactive lifestyle and poor nutrition. It is now apparent that for the first time in U.S. history, our children will lead a shorter, lower quality of life than their parents. The reason? We now live in what health practitioners call an “obesity epidemic.

260p crius75 02-01-2013 64 6   Download

Any attempt to improve the efficiency of AI has to be based on an understanding of the most important causes for failure under each specific production system. The traditional methods used for this rely on accurate recording and analysis of reproductive events such as oestrus, services, pregnancies and calvings. However, records are rarely kept by smallholders and, even when available, do not allow an assessment of the importance of factors such as efficiency and precision of oestrus detection by the farmers or incorrect timing of insemination.

0p thankinhphanliet 21-12-2012 46 2   Download

Fornari and Mele (2009) provide a detailed assessment of the out of sample forecasting ability of univariate linear and non linear models which rely on financial indicators. Overall, their conclusion is that the term spread, together with a time-varying measure of stock market volatility, does a rather good job in anticipating the rates of change in the US post-War industrial production index.

63p bocapchetnguoi 05-12-2012 78 3   Download

Responses to the Council's consultation document demonstrated how many of these ethical values may be interpreted in diverse and sometimes contradictory ways. This potential for conflicts in usage does not mean that these values are made redundant; but rather that the way they are being used in particular circumstances needs to be made explicit and, where necessary, justified.

35p quaivatdo 15-11-2012 48 0   Download

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học Journal of Biology đề tài: Developmental time at which spontaneous, X-ray-induced and EMS-induced recessive lethal mutations become effective in Drosophila melanogaster

0p toshiba20 12-11-2011 35 1   Download

Although radiation can interfere with many cellular processes, many experts feel that a cell must undergo a double-strand DNA break from radiation in order to be killed. The factors that influence tumor cell killing include the D0 of the tumor (the dose required to deliver an average of one lethal hit to all the cells in a population), the Dq of the tumor (the threshold dose—a measure of the cell's ability to repair sublethal damage), hypoxia, tumor mass, growth fraction, and cell cycle time and phase (cells in late G1 and S are more resistant). Rate of clinical response...

5p konheokonmummim 03-12-2010 54 3   Download

A s of this writing , there have been 169 laboratory-confirmed human cases of H5N1 influenza – avian flu–and 91 of those people have died. It is impossible to know whether this particular strain of flu will mutate in such a way as to be easily transmissible between people and whether the virus will remain as lethal as it currently is. But if those things happen and a pandemic ensues, then, “in the best of circumstances,” the World Health Organization says, it would kill 2 million to 7.4 million people. In a worst-case scenario, more than 100 million would die, several times...

106p theboy_ldv 13-06-2010 140 21   Download