Lifetime disease burden

Anterior cruciate ligament rupture (ACLR) is a debilitating and potentially life-changing condition in humans, as there is a high prevalence of early-onset osteoarthritis after injury. Identification of high-risk individuals before they become patients is important, as post-treatment lifetime burden of ACLR in the USA ranges from $7.6 to $17.7 billion annually. ACLR is a complex disease with multiple risk factors including genetic predisposition.

10p vinarcissa 21-03-2023 4 2   Download

It is essential to have information on the disease burden of lung cancer at an individual level throughout the life; however, few such results have been reported. Thus, this study aimed to assess the lifetime disease burden in patients with lung cancer by assessing various factors, such as survival, years of life lost (YLL) and medical expenditure in South Korea based on real-world data and extrapolation.

10p viamsterdam 18-09-2020 8 0   Download

Bronchopulmonary dysplasia (BPD) is among the most severe chronic lung diseases and predominantly affects premature infants. There is a general understanding of BPD’s significant impact on the short-term outcomes however there is little evidence on long-term outcomes.

10p vimax2711 27-03-2020 18 1   Download

Almost one in six people in the UK will suffer from mental ill-health, such as anxiety or depression, in their lifetime. i Mental ill-health can cause, and be caused by, health and social inequalities. It accounts for almost 20% of the burden of disease in Europe. ii Poor mental health also costs the economy an estimated £26.1 billion a year, because of the thousands of people unable to work due to their mental illness.

37p quygia123 06-11-2012 42 1   Download

The number of people with diabetes mellitus (DM) has been conservatively estimated to approximately double by 2030 to a worldwide prevalence of 4.4% at which time 366 million people will have diabetes (Wild et al., 2004). As the number of people with DM rises, so too will the burden of diabetic foot disease, particularly since the factors contributing to ulcer formation such as peripheral neuropathy and vascular disease are already present in 10% of people at the time of diagnosis (Boulton et al., 2005).

0p maket1311 16-10-2012 59 3   Download

Schizophrenia is arguably the most serious major psychiatric disorder, usually developing in late adolescence or early adulthood, and often having a profound effect over the lifetime on daily functioning. People with schizophrenia frequently have difficulties living independently and caring for themselves, working or attending school, fulfilling parental or other role obligations, and enjoying close relationships and rewarding leisure activities (American Psychiatric Association, 2000).

670p ozon_ozon 02-05-2012 77 9   Download