Litchfield Wilcoxon method

This study aimed to assess the acute and subchronic toxicity of Pyridostigmine bromide 90 mg extended-release tablets in experimental animals. Subjects and methods: Pyridostigmine bromide 90 mg extended-release tablets were prepared complying in-house specifications. Acute oral toxicity (LD50) was determined in white mice using the Litchfield-Wilcoxon method. Subchronic toxicity was assessed in rabbits following OECD guidelines.

5p vipanly 28-10-2024 0 0   Download

This research is conducted to evaluate the acute and subchronic toxicities of the extract of Jasminum subtriplinvere Blume leaves through oral administration in experimental animals. The acute toxicity was determined by the Litchfield Wilcoxon method in Swiss mice.

12p vinatisu 23-08-2024 3 1   Download

To evaluate the acute toxicity and semi-chronic toxicity of the remedy “Bo phe dinh suyen QY” on experimental animals. Subjects and methods: The remedy “Bo phe dinh suyen QY” meeting basic standards was used to evaluate for acute toxicity in Swiss white mice, and for semi-chronic toxicity in Wistar white rats. Acute toxicity was assessed according to the Litchfield-Wilcoxon method. Sub-chronic toxicity was assessed according to the guidance of the Ministry of Health of Vietnam.

4p viohoyo 02-04-2024 7 4   Download