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Localized disease
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This study aimed to investigate the characteristics and clinical outcomes in a series of patients with extremity soft tissue sarcoma (STS) who underwent amputation at a large East Asian referral center.
9p
vishanshan
27-06-2024
1
1
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Esophageal carcinoma is a type of cancer that occurs in the esophagus. For patients with locally advanced or metastatic esophageal squamous cell carcinoma who have either experienced disease progression following first-line standard chemotherapy or are intolerant to it, the prognosis is typically poor.
13p
vishanshan
27-06-2024
1
1
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The prognostic significance of mast cells and different phenotypes of macrophages in the microenvironment of hepatocellular carcinoma (HCC) following resection is unclear. We aimed in this study to assess the local distribution of infiltrating macrophages and mast cells of specific phenotypes in tissues of HCC and to evaluate their prognostic values for survival of post-surgical patients.
13p
vikoch
27-06-2024
2
1
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Developing countries have a significantly higher incidence of breast cancer in patients younger than 40 years as compared to developed countries. This study aimed to examine if young age at diagnosis is an independent prognostic factor for worse survival outcomes in breast cancer as well as the effect of age on Disease-free survival (DFS) and local recurrence free survival (LRFS) after adjusting for various tumor characteristics, local and systemic treatments.
8p
vikoch
27-06-2024
2
1
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Pancreatic neuroendocrine tumors (PANETs) are rare, slow growing cancers that often present with local and distant metastasis upon detection. PANETS contain distinct karyotypes, epigenetic dysregulation, and recurrent mutations in MEN1, ATRX, and DAXX (MAD+); however, the molecular basis of disease progression remains uncharacterized.
15p
vibransone
28-03-2024
6
2
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Pancreatic cancer (PC) is a complex disease in which both non-genetic and genetic factors interplay. To date, 40 GWAS hits have been associated with PC risk in individuals of European descent, explaining 4.1% of the phenotypic variance.
18p
vibransone
28-03-2024
3
1
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Currently, over half of breast cancer cases are unrelated to known risk factors, highlighting the importance of discovering other cancer-promoting factors. Since crosstalk between gut microbes and host immunity contributes to many diseases, we hypothesized that similar interactions could occur between the recently described breast microbiome and local immune responses to influence breast cancer pathogenesis.
17p
vibransone
28-03-2024
3
1
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Vaginal microbiota (VMB) composition is altered in women with cervical intra-epithelial neoplasia (CIN) compared to healthy controls and is associated with disease progression. However, the impact of CIN excision on the VMB and innate immunity is not known. This observational study aims to explore the impact of CIN excision on the VMB, antimicrobial peptides (AMP) and proinflammatory cytokines.
18p
vibransone
28-03-2024
2
1
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The Colombian population, as well as those in other Latin American regions, arose from a recent tricontinental admixture among Native Americans, Spanish invaders, and enslaved Africans, all of whom passed through a population bottleneck due to widespread infectious diseases that left small isolated local settlements.
22p
viellison
28-03-2024
3
2
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Metabolic pathways are related to physiological functions and disease states and are influenced by genetic variation and environmental factors. Hispanics/Latino individuals have ancestry-derived genomic regions (local ancestry) from their recent admixture that have been less characterized for associations with metabolite abundance and disease risk.
13p
vicwell
29-02-2024
5
1
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Ebook "Small animal neuroanatomic lesion localization practice book" includes content: How to use this book, introduction to the neurologic examination, neuroanatomic lesion localization, intracranial disease, spinal cord disease, neuromuscular disease, multifocal disease.
214p
muasambanhan07
20-02-2024
5
0
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Ebook "Environmental Geochemistry and Health with special reference to developing countries" presents a range of papers by geochemists, nutritionists, medical and veterinary researchers that illustrate the relevance of environmental geochemistry to the study of human and animal health problems in developing countries. People in these areas are very dependent on localized sources of water and food, and any geochemical anomaly (enrichment or depletion) within these local environments will have a marked influence on the health of people as well as of wildlife and domesticated animals.
261p
manmanthanhla0201
27-02-2024
2
1
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Dermatomyositis is a rare autoimmune disease characterized by noninfectious inflammatory damage of skin and predominant muscles in the belts. It is believed to be associated with about 1 in 1000 cases of nasopharyngeal carcinoma. This association has been described for locally advanced stages II and III nasopharyngeal carcinoma. It has rarely been described in the early stages (stage I).
4p
vilazada
31-01-2024
3
2
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Part 2 book "Rang and Dale's pharmacology" includes content: Chemical transmission and drug action in the central nervous system, amino acid transmitters, other transmitters and modulators, neurodegenerative diseases, general anaesthetic agents, analgesic drugs, local anaesthetics and other drugs affecting sodium channels, anxiolytic and hypnotic drugs, antiepileptic drugs, antipsychotic drugs, antidepressant drugs, psychoactive drugs, drug abuse and dependence
348p
muasambanhan05
22-01-2024
4
2
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In this paper, we explore the application of FastSAM for plant disease identification by autonomous robots utilizing simultaneous localization and mapping (SLAM). We propose fine-tuning FastSAM on a dataset of plant images labelled with different disease types.
11p
vimichaelfaraday
28-12-2023
9
6
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Ebook "Mitochondria: Practical protocols (Second edition)" compiles a broad range of step-by-step protocols, complementary to the ones published in the first edition of this book, to study various aspects of mitochondrial structure and function in different model organisms, both in vitro and in vivo. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
410p
lucchinguyen
28-12-2023
4
2
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Radical nephrectomy (RN) is the standard treatment for localized renal cell carcinoma. The decrease in nephrons from RN could lead to postoperative chronic kidney disease (CKD). In this study, we aim to investigate the incidence and risk factors for CKD in patients who have received RN.
7p
vileonardodavinci
23-12-2023
3
2
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Although the prognosis of locally advanced cervical cancer has improved dramatically, survival for those with stage IIIB-IVA disease or lymph nodes metastasis remains poor. It is believed that the incorporation of intensity-modulated radiotherapy into the treatment of cervical cancer might yield an improved loco-regional control, whereas more cycles of more potent chemotherapy after the completion of concurrent chemotherapy was associated with a diminished distant metastasis.
11p
vileonardodavinci
23-12-2023
3
3
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Currently, the standard treatment for locally advanced cervical cancer is concurrent chemoradiation (CCRT). Forty percent of patients present with disease recurrence. This study aims to investigate the feasibility, safety and efficacy of neoadjuvant chemotherapy (NACT) with weekly cisplatin and paclitaxel (TP) followed by CCRT.
12p
vileonardodavinci
23-12-2023
5
2
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This study aims to investigate whether short-course radiotherapy (SCRT) followed by intensive chemotherapy improves oncologic outcomes compared with traditional preoperative long-course chemoradiotherapy (CRT).
9p
vileonardodavinci
23-12-2023
4
2
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