Medicinal biotechnology

Biotechnology is defined as biology-based technology using organisms or their parts to make or modify products or to improve characteristics of plants, animals, and microorganisms for the demands of human beings. This article reviews the current research, challenges, and perspectives of biotechnology as an integration of both life sciences and applied sciences.

11p vibecca 01-10-2024 3 1   Download

Genetic screens have been the lifeblood of forward genetics. They have enabled widespread discoveries of gene function, leading to meaningful advances in medicine, biotechnology, and agriculture. Nevertheless, technologies for performing these screens have been limited by scale, specificity, and targeting range of tools for investigating and perturbing the genome.

4p vimichaelfaraday 25-03-2022 15 1   Download

The present research was carried out to determine the anatomical features of leaves of Alangium salviifolium and their endophytic fungal association. Alangium salviifolium is an important medicinal plant with various activities reported. It is suggested that the medicinal property of the plant is either because of their endophytes or the endophytes inherit the medicinal properties from their host plant. Hence the detailed study of plant- microbe interaction is important.

5p mudbound 10-12-2021 8 1   Download

The document English in Pharmacy - Part 2 include all of the following: Biotechnology and biopharmaceuticals, biosimilar medicines, prescritions inserts, reading OTC medicines labels, most common forms of medication, types of medication,...

34p tangtuy14 04-06-2016 190 54   Download

The design of b-glycosidases with planed substrate specificity for biotechnological application has received little attention. This is mostly a consequence of the lack of data on the molecular basis of the b-glycosidase specificity, namely data on the energy of the noncovalent interactions in the enzymetransition state complex. In an attempt to fill this gap, sitedirected mutagenesis and enzyme steady-state kinetic experiments with different substrates were conducted, using as model a digestive b-glycosidase (glycoside hydrolase family 1) from Spodoptera frugiperda (Lepidoptera) (Sfbgly50).

10p system191 01-06-2013 39 4   Download

Laboratory for Lipoprotein Chemistry and 4Flanders Interuniversity Institute for Biotechnology, Department of Medical Protein Research, Faculty of Medicine, Department of Biochemistry, Ghent University, Belgium; 2Laboratory of Biomolecular Dynamics, Katholieke Universiteit Leuven, Belgium; 3Ecole Normale Supe´rieure, Paris, France Penetratin is a 16-amino-acid peptide, derived from the homeodomain of antennapedia, a Drosophila transcription factor, which can be used as a vector for the intracellular delivery of peptides or oligonucleotides....

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Affinity reagents capable of selective recognition of the different human immunoglobulin isotypes are important detection and purification tools in biotechnology. Here we describe the development and characterization of affinity proteins (affibodies) showing selective binding to human IgA. From protein libraries constructed by combinatorial mutagenesis of a 58-amino-acid, three-helix bundle domain derived from the IgG-binding staphylococcal protein A, variants showing IgA binding were selected by using phage display technology and IgA monoclonal antibodies (myeloma) as target molecules. ...

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Equilibrium studies on the acid included denaturation of stem bromelain (EC 3.4.22.32) were performed by CD spectroscopy, ¯uorescence emission spectroscopy and binding of the hydrophobic dye, 1-anilino 8-naphthalene sulfonic acid (ANS). At pH 2.0, stembromelain lacks awell de®ned tertiary structure as seen by ¯uorescence and near-UVCDspectra.Far-UVCDspectra showretentionof some native like secondary structure at pH 2.0. Interdisciplinary Biotechnology Unit, Aligarh Muslim University, India Equilibrium studies on the acid included denaturation of stem bromelain (EC 3.4.22.

6p research12 29-04-2013 32 3   Download

An applied field of biology that involves the use of living organisms and bioprocesses in engineering, technology, medicine and other fields requiring bioproducts. (http://en.wikipedia.org/wiki/Biotechnology) It is the products and exploitation from other fundamental sciences.Traditional Biotechnology Traditional biotechnology refers to a number of ancient ways of using living organisms to make new products or modify existing ones. In its broadest definition, traditional biotechnology can be traced back to human's transition from hunter-gatherer to farmer.

29p zingzing09 24-04-2013 63 8   Download

Microorganisms produce a large number of pharmaco-logically and biotechnologically important peptides by using nonribosomal peptide synthetases (NRPSs). Due to their modular arrangement and their domain organization NRPSs are particularly suitable for engineering recom-binant proteins for the production of novel peptides with interesting properties.

9p fptmusic 12-04-2013 60 3   Download

Proteins from organisms living in extreme conditions are of particular interest because of their potential for being templates for redesign of enzymes both in biotechnological and other industries. The crystal struc-ture of a proteinase K-like enzyme from a psychrotroph Serratiaspecies has been solved to 1.8 A˚ .

11p dell39 27-03-2013 37 2   Download

T4 DNA ligase is one of the workhorses of molecular biology and used in various biotechnological applications. Here we report that this ligase, unlikeEscherichia coliDNA ligase,TaqDNA ligase and Ampligase, is able to join the ends of single-stranded DNA in the absence of any duplex DNA structure at the ligation site.

10p dell39 27-03-2013 44 3   Download

Understanding the structural basis of thermostability and thermoactivity, and their interdependence, is central to the successful future exploitation of extremophilic enzymes in biotechnology. However, the structural basis of thermostability is still not fully characterized.

11p media19 04-03-2013 25 4   Download

The phosphotransferase system inEscherichia coliis a transport and sen-sory system and, in this function, is one of the key players of catabolite repression. Mathematical modelling of signal transduction and gene expres-sion of the enzymes involved in the transport of carbohydrates is a promis-ing approach in biotechnology, as it offers the possibility to achieve higher production rates of desired components.

9p vinaphone15 27-02-2013 36 2   Download

One ot the most representative (sub)tropical soil microbe,Chro-mobacterium violaceum, produces many important substances and has great potential for biotechnology and medicine. On the other hand, it can also act as an opportunistic human pathogen. The bacterium produces the lectin CV-IIL, that can help the adhesion bacterium to saccharide moieties at host cells¢ surface.

39p cosis54 05-01-2013 43 4   Download

Systems biology has received an ever increasing interest during the last decade. A large amount of third-party funding is spent on this topic, which involves quantitative experimentation integrated with computational modeling. Industrial companies are also starting to use this approach more and more often, especially in pharmaceutical research and biotechnology.

91p cosis54 04-01-2013 46 5   Download

L Aravind, Lakshminarayan M Iyer, Detlef D Leipe and Eugene V Koonin Address: National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA. reviews Correspondence: L Aravind. E-mail: aravind@ncbi.nlm.nih.gov Published: 16 April 2004 Genome Biology 2004, 5:R30 The electronic version of this article is the complete one and can be found online at http://genomebiology.com/2004/5/5/R30 Received: 19 January 2004 Revised: 8 March 2004 Accepted: 11 March 2004 reports © 2004 Aravind et al.

0p thulanh21 15-11-2011 58 2   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: Center for Biotechnology and Genomic Medicine, Medical College of Georgia...

0p thulanh20 12-11-2011 39 1   Download

PubMed giúp bạn tìm kiếm trong hơn 15 triệu trích dẫn và tóm tắt văn bản chuyên ngành y, điều dưỡng, nha, thú y, hệ thống chăm sóc sức khỏe và khoa học cận lâm sàng. Nó cung cấp truy cập vào MEDLINE® và các bài báo trong các tạp chí y khoa được tuyển chọn không có trong MEDLINE. PubMed là một nguồn tài liệu miễn phí. Nó được NCBI (National Center for Biotechnology Information - Trung tâm Thông tin Công nghệ Sinh học Quốc gia), thuộc NLM (National Library of Medicine - Thư viện Y khoa Quốc...

42p huyhoangytn 19-08-2011 2635 110   Download

Table 62-1 Selected Databases Relevant for Genomics and Genetic Disorders Site URL Comment National Center Biotechnology Information (NCBI) for http://www.ncbi.nlm.nih.gov/ Molecular biology information, public databases, computational Site URL Comment biology. for Software analyzing genome data. Extensive links to other databases, genome resources, tutorials and National Human Genome http://www.genome.gov/ Web providing links Research Institute information about the human genome sequence, genomes of other organisms, and research genomic ...

10p konheokonmummim 03-12-2010 75 3   Download