Memory against

We present SeqOthello, an ultra-fast and memory-efficient indexing structure to support arbitrary sequence query against large collections of RNA-seq experiments. It takes SeqOthello only 5 min and 19.1 GB memory to conduct a global survey of 11,658 fusion events against 10,113 TCGA Pan-Cancer RNA-seq datasets.

13p vigalileogalilei 27-02-2022 4 1   Download

Human immunological memory is a hallmark of the adaptive immune system and plays an important role in the development of effective immune responses against tumors. In the present study, we aimed to determine the frequencies of CD8+ memory T cell subsets including T stem cell memory (TSCM) in tumor-draining lymph nodes of patients with breast cancer (BC).

9p vijakarta2711 09-06-2020 17 1   Download

The nature of bovines` life enable them to form developed immune responses due to their exposure to many pathogens, besides their immune organs` characteristics. Bovine are herbivorous animals which make them a rich and safe source for human's therapies. The potential role of bovine in providing humans with antibodies in serum and milk in particularly the specific antibodies against human viruses or even relevant bovine viruses cannot be denied.

5p caygaocaolon2 11-03-2020 11 0   Download

Treatment of castration-resistant prostate cancer (CRPC) patients with androgen deprivation therapy puts prostate cancer in remission while treatment with already available drugs in market including abirater one help in controlling advanced prostate cancers for sometime though fail to respond, evolve resistance mechanisms, and undergo genetic deregulations later on with poor patient survival rate and no cure.

24p nguathienthan2 26-12-2019 12 0   Download

Undesirable and desirable effects of stressors on the body are assigned to distress and eustress, respectively. Immune system and brain are the most susceptible parts to stressful conditions, whereas longlasting alterations in putative immune proteins involved in tension such as corticosterone (CORT), interleukin 6 (IL-6), and tumor necrosis factor-alpha (TNF-a) can impact learning and memory. Intermittent fasting (IF) is a repeated regular cycle of dietary restriction with well-known beneficial properties on the body.

5p trinhthamhodang1 14-11-2019 29 2   Download

Substantial evidence has shown that most cases of memory impairment are associated with increased neuroinflammation and oxidative stress. In this study, the potential of a standardised Andrographis paniculata aqueous extract (APAE) to reverse neuroinflammation and cognitive impairment induced by lipopolysaccharide (LPS) was examined in vivo. Rats were treated with APAE (50, 100, 200, and 400 mgkg 1 , p.o.) for 7 consecutive days prior to LPS (1 mgkg 1 , i.p.)-induced neuroinflammation and cognitive impairment.

11p caygaocaolon1 13-11-2019 27 0   Download

Network intrusion detection system is used to inspect packet contents against thousands of predefined malicious or suspicious patterns. Because traditional software alone pattern matching approaches can no longer meet the high throughput of today’s networking, many hardware approaches are proposed to accelerate pattern matching.

9p dunglh2013 02-04-2014 44 1   Download

This paper proposes an efficient division algorithm protected against simple side-channel analysis. The proposed algorithm applies equally well to software and hardware implementations. Furthermore, it does not impact the running time nor the memory requirements.

10p dunglh2013 02-04-2014 55 0   Download

The pre-service teachers in the writing methods course learned about the history of writing instruction and writing theories, writers’ workshops and the use of various types of journals. They were also introduced to the role of literature and methods for integrating oral skills into literacy instruction. In addition to these materials, I reviewed sample ESL student essays to illustrate techniques for providing feedback on student writing.

0p commentcmnr 03-06-2013 52 7   Download

Theenvironmental impactsofbiomassutilisation forenergyand industrialproductsarequite significant, and are arguably greater in scale and scope than any other class of energy resources—renewable or non
renewable—due to the intensive use of land, water and other resources.Unlikefossilresources,however,theimpactscanbepositiveornegative,depending on the effect on soils, local ecology, and nutrients.

0p loixinloi 08-05-2013 43 4   Download

The mechanical bypass uses a slotted rod that is actuated by a lever on the large dashpot plunger shaft to provide another leakage path in the dashpot. The lever is positioned so that the bypass opens at a gate position above speed no load, when the unit is normally on line. If it is necessary to operate isolated, the bypass arm is moved out of the way and the unit dashpot will function normally. The solenoid operated dashpot bypass provides a leakage path in the dashpot when the solenoid is energized. The rate of leakage is...

52p loixinloi 08-05-2013 52 1   Download

In Ethiopia, to meet the ever-increasing demand for milk, milk products and beef and thus contribute to economic growth, genetic improvement of the indigenous cattle has been proposed as one of the options. Genetic improvement of the indigenous cattle, basically focusing on crossbreeding, has been practised for the last five decades but with little success. Selection as an improvement tool has been given less emphasis. There are no systematic and organized selection schemes for cattle genetic improvement in Ethiopia.

0p conduongdinhmenh 07-05-2013 30 4   Download

The large-scale rural farms producing on a commercial basis in Pakistan are among the lowest cost farms in the world, driven by low cost of labor and feed. This has been reported in IFCN9 2004. While still limited in number, the big commercial farms of Pakistan have major economic benefits. Existing commercial farms need to boost their current level of mechanization, automation and refrigeration (cold chains), in order to be more productive.

27p conduongdinhmenh 07-05-2013 32 6   Download

I PURPOSE to write the history of England from the accession of King James the Second down to a time which is within the memory of men still living. I shall recount the errors which, in a few months, alienated a loyal gentry and priesthood from the House of Stuart. I shall trace the course of that revolution which terminated the long struggle between our sovereigns and their parliaments, and bound up together the rights of the people and the title of the reigning dynasty.

301p nhokheo9 06-05-2013 56 3   Download

For example, the report shows that 64% of countries have developed integrated water resources management plans and 34% report an advanced stage of implementation. However, progress appears to have slowed, or even regressed, in low and medium Human Development Index (HDI) countries since the last survey carried out in 2008. Much remains to be done to finance and implement plans in many HDI countries. The Rio+20 conference has chosen Green Economy in the context of sustainable development and poverty eradication as an overarching theme for realizing transformational change.

75p seketnoi 26-04-2013 44 1   Download

Tham khảo sách 'diagnosis and management of head and neck cancer', y tế - sức khoẻ, y dược phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả

96p seketnoi 26-04-2013 51 2   Download

There is no published evidence and conflicting expert opinion on the treatment of malnourished patients, and the specification and treatment of “at-risk” patients (those with diarrhoea, vomiting, physical illness, weight loss, poor diet), with the majority of experts recommending parenteral vitamin supplementation during detoxification.

33p seketnoi 26-04-2013 46 5   Download

WHO has not reviewed the safety, efficacy, quality, applicability, or cost acceptability of any of the technologies referred to hereafter. Therefore, inclusion of the aforesaid fact sheets herein does not constitute a warranty of the fitness of any technology or of any resulting product and any future development thereof, for a particular purpose. Besides, the responsibility for the quality, safety and efficacy of each technology or each resulting product remains with its developer, owner and/or manufacturer.

7p dacotaikhoan 25-04-2013 39 7   Download

Birds are housed in large structures with floor areas ranging from 12,000 square feet to more than 20,000 square feet. Buildings have automated feeders and either bell-type, nipple, or cup watering systems. Broilers and turkeys are raised on deep litter (wood shavings) in open-floor environments where birds can move freely throughout the house. A production cycle for broilers generally lasts six weeks, after which birds are removed to market.

15p loginnhanh 22-04-2013 44 2   Download

Selecting generation after generation of birds for their faster growth rates and higher meat yields has left the birds’ immune systems less able to cope with infections and there is a high degree of genetic uniformity in the population, making spread of the virus all the more easy. Further intensification of the industry has been suggested by some as the solution to avian flu, on the rationale that keeping birds indoors will prevent contamination. However, this relies on perfect, fail-safe biosecurity – and such measures are near impossible to implement.

13p loginnhanh 22-04-2013 41 2   Download