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Mesenchymal progenitor cell proliferation
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With the unprecedented rapid growth rate (up to 2.75 cm/day), velvet antler is an invaluable model for the identification of potent growth factors and signaling networks for extremely fast growing tissues, mainly cartilage.
13p
visilicon2711
20-08-2021
4
1
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Recent studies have highlighted the contribution of senescent mesenchymal and epithelial cells in Idiopathic Pulmonary Fibrosis (IPF), but little is known regarding the molecular mechanisms that regulate the accumulation of senescent cells in this disease.
16p
vimaine2711
26-03-2021
9
1
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Patients with systemic sclerosis (SSc) are endagered by tissue fibrosis and by microvasculopathy, with the latter caused by endothelial cell expansion/proliferation. SSc-associated fibrosis potentially results from mesenchymal transdifferentiation of endothelial cells.
9p
vioregon2711
22-02-2021
20
4
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Adult stem cells are crucial for maintaining proper function and repair of tissues. The epithelium of the adult mammalian intestine is a constant dialog with its underlying mesenchyme to direct progenitor proliferation, lineage commitment, terminal differentiation and ultimately cell death. The epithelium is shaped into spatially distinct compartments that are dedicated to each of these events. The unique intestinal orchestration makes the crypt as one of the most accessible models for the study of adult stem cell biology (Barker et al., 2007).
5p
kequaidan4
05-05-2020
12
0
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The vascular niche is a site rich in blood vessels, whereas endothelial cells, pericytes, and smooth muscle cells create a microenvironment that recruits mesenchymal stem cells (MSCs) and hematopoietic stem cells (HSCs), which is important for stem cell mobilization, proliferation, and differentiation. In this study, CD146 + pericytes were purified and enriched from the human umbilical cord vein.
10p
nutifooddau
27-01-2019
22
2
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