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Metabolic dysfunctions
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Ebook "Mitochondria and cancer" presents thorough analyses of mitochondrial dysfunction as one of the hallmarks of cancer, discusses the clinical implications of mitochondrial defects in cancer, and as unique cellular targets for novel and selective anti-cancer therapy. These include differences in mitochondrial metabolic activity, molecular composition of mitochondria and mtDNA sequence, as well as in alteration of nuclear genes encoding mitochondrial proteins.
294p
ladongphongthanh1008
22-04-2024
3
1
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Midbrain dopaminergic neurons (MDN) represent 0.0005% of the brain’s neuronal population and mediate cognition, food intake, and metabolism. MDN are also posited to underlay the neurobiological dysfunction of schizophrenia (SCZ), a severe neuropsychiatric disorder that is characterized by psychosis as well as multifactorial medical co-morbidities, including metabolic disease, contributing to markedly increased morbidity and mortality.
19p
vibransone
28-03-2024
8
2
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Exercise training is well established as the most effective way to enhance muscle performance and muscle building. The composition of skeletal muscle fiber type affects systemic energy expenditures, and perturbations in metabolic homeostasis contribute to the onset of obesity and other metabolic dysfunctions.
21p
vibransone
28-03-2024
3
2
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Ebook "Diabetic cardiomyopathy: Biochemical and molecular mechanisms" is a compilation of review articles devoted to the study on the topic with respect to biochemical and molecular mechanisms of hyperglycaemia. The wide range of areas covered here is of interest to basic research scientists, clinicians and graduate students, who are devoted to study the pathogenesis of diabetes-induced cardiovascular dysfunction. Furthermore, some chapters are directed towards increasing our understanding of novel ways for the prevention/treatment of cardiomyopathy.
423p
manmanthanhla0201
26-02-2024
3
1
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Part 2 book "Mutraceuticals in veterinary medicine" includes content: Nutraceuticals in arthritis, nutraceuticals for antiaging, nutraceuticals for cognitive dysfunction, nutraceuticals for calming and stress, nutraceuticals in cardiovascular diseases, nutraceuticals in hepatic and pancreatic diseases,.... and other contents.
492p
oursky06
17-10-2023
3
1
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Adipose tissue is recognized as a highly active metabolic and endocrine organ. The hormones secreted by this tissue play an important role in many biochemical processes. It is known that dysfunction of adipocytes can cause insulin resistance, type 2 diabetes or hyperlipidemia.
7p
vinarcissa
21-03-2023
5
1
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We hypothesize higher air pollution and fewer greenness exposures jointly contribute to metabolic syndrome (MetS), as mechanisms on cardiometabolic mortality. Methods: We studied the samples in the Chinese Longitudinal Healthy Longevity Survey. We included 1755 participants in 2012, among which 1073 were followed up in 2014 and 561 in 2017.
12p
viferrari
28-11-2022
11
2
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Part 1 of ebook "Frontiers in gynecological endocrinology (Volume 1: From symptoms to therapies)" provide readers with content about: menstrual dysfunction in young women; metabolism, hyperandrogenism, body weight and reproduction; ovarian stimulation, surgery and insufficiency;... Please refer to the part 1 of ebook for details!
121p
duonghoanglacnhi
07-11-2022
23
8
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Pregnancy is considered as a test for beta cell reserve. If there is a good function, insulin resistance will overcome. If not, gestational diabetes will occur. Insulin resistance (IR) present in normal pregnancy is required to provide nutrients to the growing fetus. There is a rapid increase of insulin in such an insulin resistant state.
5p
viporsche
28-10-2022
7
2
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Non-alcoholic fatty liver disease (NAFLD) is represented as the most common liver disease worldwide. NAFLD is associated with metabolic risk factors underpinned by insulin resistance, inflammation and endothelial dysfunction, leading to extrahepatic changes in central nervous diseases such as cognitive impairment, Alzheimer’s disease and dementia. The aim of the review is to explore the association between NAFLD and cognitive function.
19p
vinobelprisen
26-03-2022
17
5
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Higher muscle echo intensity (EI) reflects higher content of fat and/or connective tissue within skeletal muscle, eventually inducing lower muscle strength, physical dysfunction, and metabolic impairment. Continuous exercise decreases muscle EI in older individuals; however, it is not well understood how several months’ rehabilitation exercise affects gradation-based EI.
9p
vinobelprisen
26-03-2022
19
4
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Skin barrier dysfunction plays a key role in atopic dermatitis (AD). This impairment is related to altered composition and metabolism of epidermal sphingolipids and a deficiency of ceramides. Glycosaminoglycans (GAGs), and especially hyaluronic acid, could be useful in the management of AD.
10p
vigalileogalilei
28-02-2022
8
2
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Insulin dysregulation (ID) is a key risk factor for equine endocrinopathic laminitis, but in many cases ID can only be assessed accurately using dynamic tests. The identification of other biomarkers could provide an alternative or adjunct diagnostic method, to allow early intervention before laminitis develops.
10p
vidarwin
23-02-2022
14
2
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Primary graft dysfunction (PGD) is the main cause of death in the first 30days after heart transplanta‑ tion (HTX), accounting for approximately 40% of mortality. The study’s primary aim was to assess the incidence of PGD, following the International Society for Heart and Lung Transplantation consensus, and to compare it with the incidence of significant postoperative hypotension despite administration of high-dose inotropes and vasocon‑ strictors.
9p
vidietmarhopp
28-12-2021
5
0
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Adipose tissue is a major endocrine organ and is thought to play a central role in the metabolic control of reproductive function in cattle. Plane of nutrition during early life has been shown to influence the timing of puberty in both male and female cattle, though the exact biological mechanisms involved are currently unknown. The aim of this study was to investigate the effect of early calf-hood nutrition on the transcriptomic profile of subcutaneous adipose tissue in Holstein-Friesian bulls to identify possible downstream effects on reproductive physiology.
12p
vibeauty
23-10-2021
12
1
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Fatty liver disease prevalently occurs in commercial postpartum dairies, resulting in a worldwide high culling rate because of their subsequent limitations of production and reproduction performance.
16p
vitzuyu2711
29-09-2021
20
1
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Pompe disease is a progressive metabolic myopathy. Involvement of respiratory muscles leads to progressive pulmonary dysfunction, particularly in supine position. Diaphragmatic weakness is considered to be the most important component.
7p
vimontana2711
05-04-2021
6
2
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Skeletal muscle function dysfunction has been reported in patients with cystic fibrosis (CF). Studies so far showed inconclusive data whether reduced exercise capacity is related to intrinsic muscle dysfunction in CF. Methods: Twenty patients with CF and 23 age-matched controls completed an incremental cardiopulmonary cycling test. Further, a Wingate anaerobic test to assess muscle power was performed.
11p
vimaine2711
26-03-2021
10
2
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The metabolic syndrome refers to the co-occurrence of or clustering of several known cardiovascular risk factors, including insulin resistance, abdominal adiposity, atherogenic dyslipidemia and endothelial dysfunction. These conditions are interrelated and share underlying mechanisms and pathways. It identifies a subgroup of patients with shared pathophysiology who are at high risk of developing cardiovascular disease, hypertension and type II diabetes.
6p
trinhthamhodang9
16-12-2020
12
2
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Rash, liver dysfunction, and diarrhea are known major adverse events associated with erlotinib and gefitinib. However, clinical trials with gefitinib have reported different proportions of adverse events compared to trials with erlotinib. In an in vitro study, cytochrome P450 (CYP) 2D6 was shown to be involved in the metabolism of gefitinib but not erlotinib.
9p
vijisoo2711
30-09-2020
3
1
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