Metabolic mechanisms

Understanding the metabolic changes in colorectal cancer (CRC) and exploring potential diagnostic biomarkers is crucial for elucidating its pathogenesis and reducing mortality. Cancer cells are typically derived from cancer tissues and can be easily obtained and cultured.

13p vishanshan 27-06-2024 1 1   Download

This study aims to identify functionally relevant lncRNAs impacting OS proliferation and lipid metabolism and seeks to shed light on the upstream regulatory mechanisms governing lipogenic enzyme activity. Based on comprehensive bioinformatic analysis and the establishment of a risk model, we identified seven lncRNAs signifcantly associated with clinical characteristics and lipid metabolism-related genes in patients with OS.

15p vikoch 27-06-2024 1 1   Download

Part 1 book "Rang and Dale's pharmacology" includes content: Cell proliferation, apoptosis, repair and regeneration; cellular mechanisms; method and measurement in pharmacology; drug absorption and distribution; drug metabolism and elimination; pharmacokinetics; pharmacogenetics, pharmacogenomics and ‘personalised medicine’; chemical mediators and the autonomic nervous system,... and other contents.

357p dianmotminh03 03-06-2024 3 0   Download

Ebook "Discovering biomolecular mechanisms with computational biology" present critical reviews of methods and high-impact applications in computational biology that lead to results that also non-bioinformaticians must know to design efficient experimental research plans. Discovering Biomolecular Mechanisms with Computational Biology also summarizes non-trivial theoretical predictions for regulatory and metabolic networks that have received experimental confirmation.

152p ladongphongthanh1008 22-04-2024 8 2   Download

Ebook "The long and short noncoding RNAs in cancer biology" conveys a comprehensive knowledge of long and short ncRNAs in cancer regulation and their potentials as diagnostic biomarkers and therapeutic targets. Topics covered include the molecular mechanisms of various classes of ncRNAs (with emphasis on long non-coding RNAs and microRNAs) in cancer, the functional roles of ncRNAs in regulating different cancer hallmarks (including proliferation, apoptosis, stem-cell properties, epithelial-mesenchymal transition, metabolism, angiogenesis, tumor-host interactions and therapeutic resistance).

455p tracanhphuonghoa1007 22-04-2024 4 2   Download

Genome-wide association studies (GWAS) have identified more than 100 genetic loci associated with type 2 diabetes (T2D). However, the underlying biological mechanisms for many of these associations remain unknown. GWAS signals close to the glucokinase regulatory protein gene (GCKR) have been reported for lipid and glucose metabolism traits and the risk of T2D.

14p vioraclene 31-03-2024 3 2   Download

The genetic regulation of metabolic phenotypes (i.e., metabotypes) in type 2 diabetes mellitus occurs through complex organ-specific cellular mechanisms and networks contributing to impaired insulin secretion and insulin resistance. Genome-wide gene expression profiling systems can dissect the genetic contributions to metabolome and transcriptome regulations.

15p vioraclene 31-03-2024 4 2   Download

The human gut harbors trillions of microbes that play dynamic roles in health. While the microbiome contributes to many cardiometabolic traits by modulating host inflammation and metabolism, there is an incomplete understanding regarding the extent that and mechanisms by which individual microbes impact risk and development of cardiovascular disease (CVD).

16p vibransone 28-03-2024 9 2   Download

Ebook "Protein modelling" detailed description of cutting-edge computational methods applied to protein modeling as well as specific applications are presented. Chapters include: the application of Car-Parrinello techniques to enzyme mechanisms, the outline and application of QM/MM methods, polarizable force fields, recent methods of ligand docking, molecular dynamics related to NMR spectroscopy, computer optimization of absorption, distribution, metabolism and excretion extended by toxicity for drugs, enzyme design and bioinformatics applied to protein structure prediction.

332p tudohanhtau1006 29-03-2024 2 1   Download

Ebook "Plants and heavy metals" focuses on the many aspects of the interaction between plants and heavy metals. Not only it describes the effects of heavy metal toxicity on the plant cell and its organs but it also examines the mechanisms that plants adopt to scavenge heavy metals at cellular, physiological, and metabolic level. Plants and Heavy Metals also analyses Hyperaccumulator plants and shows their potential role in phytoremediation technologies in light of the recent research results.

96p coduathanh1122 27-03-2024 4 1   Download

Continued part 1, part 2 of ebook BioChemistry (8th edition) provides readers with contents including: Nucleic acid biotechnology techniques; Viruses, cancer, and immunology; The importance of energy changes and electron transfer in metabolism; Carbohydrates; Glycolysis; Storage mechanisms and control in carbohydrate metabolism; The citric acid cycle; Electron transport and oxidative phosphorylation;...

451p coduathanh1122 27-03-2024 7 1   Download

Part 1 book "Advanced nutrition and human metabolism" includes content: The cell - A microcosm of life, the digestive system - mechanism for nourishing the body, carbohydrates, fiber, lipids, protein, integration and regulation of metabolism and the impact of exercise, energy expenditure, body composition and healthy weight.

323p muasambanhan08 01-03-2024 6 2   Download

Ebook "Cell death: Mechanism and disease" provides a comprehensive view of cell death, from its mechanisms of initiation and execution, to its implication in human disease and therapy. Physiological cell death plays critical roles in almost all aspects of biology, and the book details its roles in lymphocyte homeostasis, neuronal function, metabolism, and the DNA damage response. When physiological cell death goes awry, diseases can arise, and cancer is presented as a central paradigm for the consequences of derangements in the interplay between cell survival and cell death.

280p manmanthanhla0201 26-02-2024 2 1   Download

Ebook "Epigenetics in plants of agronomic importance: Fundamentals and applications (Transcriptional regulation and chromatin remodelling in plants)" provides a detailed understanding of the epigenetic mechanisms involved in plants of agronomic importance. The information presented here is significant because it is expected to provide the knowledge needed to develop in the future treatments to manipulate and selectively activate/inhibit proteins and metabolic pathways to counter pathogens, to treat important diseases and to increase crop productivity.

158p manmanthanhla0201 26-02-2024 6 1   Download

Ebook "Molecular mechanisms in yeast carbon metabolism" provides a dozen of most comprehensive reviews on the recent developments and achievements in the field of yeast carbon metabolism, from academic studies on gene expression to biotechnology relevant topics.

328p manmanthanhla0201 26-02-2024 4 1   Download

Part 1 book "Advanced nutrition and human metabolism" includes content: The cell - A microcosm of life; the digestive system - mechanism for nourishing the body; carbohydrates; fiber; lipids; protein; integration and regulation of metabolism and the impact of exercise and sport; body composition, energy expenditure, and energy balance.

331p muasambanhan08 23-02-2024 4 1   Download

Part 1 book "Brocklehurst’s textbook of geriatric medicine and gerontology" includes content: Introduction, the epidemiology of aging, the future of old age, successful aging, evolution theory and the mechanisms of aging, methodologic challenges of research in older people, geroscience, genetic mechanisms of aging, cellular mechanisms of aging, the premature aging syndrome, the neurobiology of aging - free radical stress and metabolic pathways, allostasis and allostatic overload in the context of aging, neuroendocrinology of aging,... and other contents.

365p muasambanhan08 23-02-2024 5 1   Download

Ebook "Diabetic cardiomyopathy: Biochemical and molecular mechanisms" is a compilation of review articles devoted to the study on the topic with respect to biochemical and molecular mechanisms of hyperglycaemia. The wide range of areas covered here is of interest to basic research scientists, clinicians and graduate students, who are devoted to study the pathogenesis of diabetes-induced cardiovascular dysfunction. Furthermore, some chapters are directed towards increasing our understanding of novel ways for the prevention/treatment of cardiomyopathy.

423p manmanthanhla0201 26-02-2024 3 1   Download

Ebook "DNA replication control in microbial cell factories" describes the current knowledge of biochemical mechanisms regulating initiation of DNA replication in Escherichia coli, which focuses on the control of activity of the DnaA protein. Examples of direct linkages between DNA replication and other cellular processes are provided. In addition, similarities of the mechanisms of regulation of DNA replication operating in prokaryotic and eukaryotic cells are identified, and implications for understanding more complex processes, like carcinogenesis are suggested.

56p manmanthanhla0201 27-02-2024 4 1   Download

Ebook "Bacteria-metal interactions" provides a detailed description and analysis of the reduction and metabolism of metals and metalloids by sulfate reducing bacteria. The molecular mechanisms of bacterial resistance to copper are examined as well as extracellular electron transfer and bacterial metal oxide respiration. Furthermore, in this book enrichment, isolation, and physiology of magnetotactic bacteria are discussed.

92p nhanphanguyet 28-01-2024 3 2   Download