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Metabolic medicine
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Prostate cancer (PCa) is becoming the most common malignancy in men worldwide. We investigated the effect of astragaloside IV combined with PESV on the gut microbiota and metabolite of PCa mice and the process of treating PCa.
12p
vishanshan
27-06-2024
1
1
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Part 1 book "Textbook of paediatric emergency medicine" includes content: Approach to the paediatric patient; resuscitation; trauma in children; wound management; cardiovascular; respiratory; gastroenterology and hepatology; neurology; infectious diseases; endocrine and metabolic.
273p
dianmotminh03
17-06-2024
0
0
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Positron emission tomography (PET) is a type of nuclear medicine procedure that measures the metabolic activity of cells in body tissues that is well suited for detecting, staging and monitoring malignant tumours. In this paper, the authors have successfully developed the application based on the algorithm that they proposed.
10p
viambani
18-06-2024
2
1
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Part 1 book "Rang and Dale's pharmacology" includes content: Cell proliferation, apoptosis, repair and regeneration; cellular mechanisms; method and measurement in pharmacology; drug absorption and distribution; drug metabolism and elimination; pharmacokinetics; pharmacogenetics, pharmacogenomics and ‘personalised medicine’; chemical mediators and the autonomic nervous system,... and other contents.
357p
dianmotminh03
03-06-2024
3
0
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Part 2 book "Feline emergency and critical care medicine" includes contents: Neurologic emergencies - brain, neurologic emergencies - spinal cord, neurologic emergencies - peripheral, hematologic emergencies - bleeding; hematologic emergencies - anemia; management of specific endocrine and metabolic diseases - diabetes mellitus, management of specific endocrine and metabolic diseases - other,... and other contents.
354p
dianmotminh01
14-05-2024
0
0
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Oxidoreductases (ORases) are enzymes that catalyze oxidation and reduction reactions in cells or extracellular compartments of the body. Genetic mutations and other factors that affect ORase activity have been implicated in a range of diseases, especially inherited metabolic disorders. Aldose reductase, sorbitol dehydrogenase, xanthine oxidoreductase are the ORases with relevance to diabetes pathology.
7p
dianmotminh02
03-05-2024
3
1
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Part 2 book "Illustrated textbook of pediatrics" includes content: Gastroenterology; infection and immunity; allergy; respiratory disorders; cardiac disorders; kidney and urinary tract disorders; genitalia; liver disorders; malignant disease; haematological disorders; emotions and behaviour; skin disorders; endocrine and metabolic disorders; musculoskeletal disorders; neurological disorders; adolescent medicine.
331p
zizaybay1101
30-04-2024
4
2
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Ebook "A systems biology approach to study metabolic syndrome" is to provide the target audience, specifically students of Medicine, Biology, Systems Biology and Bioinformatics, as well as experienced researchers in research fields relevant to metabolic syndrome (MetS) with an overview of the challenges and opportunities in systems biology and how it can be used to tackle MetS.
393p
ladongphongthanh1008
22-04-2024
3
2
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Part 2 book "Textbook of oral medicine, oral diagnosis and oral radiology" includes content: Dental caries, pulp and periapical lesions; gingival and periodontal diseases; regressive alterations of teeth; systemic disorders and their clinical implications; bone diseases and fibro osseous lesions; autoimmune disorders; granulomatous diseases; sexually transmitted diseases; nutritional and metabolic disorders;.... and other contents.
495p
muasambanhan10
06-04-2024
6
2
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Links between colorectal cancer (CRC) and the gut microbiome have been established, but the specific microbial species and their role in carcinogenesis remain an active area of inquiry. Our understanding would be enhanced by better accounting for tumor subtype, microbial community interactions, metabolism, and ecology.
13p
vibransone
28-03-2024
5
2
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Midbrain dopaminergic neurons (MDN) represent 0.0005% of the brain’s neuronal population and mediate cognition, food intake, and metabolism. MDN are also posited to underlay the neurobiological dysfunction of schizophrenia (SCZ), a severe neuropsychiatric disorder that is characterized by psychosis as well as multifactorial medical co-morbidities, including metabolic disease, contributing to markedly increased morbidity and mortality.
19p
vibransone
28-03-2024
8
2
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Circadian clocks are endogenous oscillators that control 24-h physiological and behavioral processes. The central circadian clock exerts control over myriad aspects of mammalian physiology, including the regulation of sleep, metabolism, and the immune system.
16p
vibransone
28-03-2024
2
1
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During aging, there is a physiological decline, an increase of morbidity and mortality, and a natural change in the gut microbiome. In this study, we investigated the influence of the gut microbiome on different metabolic parameters in adult and aged mice.
9p
vibransone
28-03-2024
2
2
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The biological importance and varied metabolic capabilities of specific microbial strains have long been established in the scientific community. Strains have, in the past, been largely defined and characterized based on microbial isolates.
16p
vibransone
28-03-2024
5
1
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The rising prevalence of type 2 diabetes (T2D) poses a major global challenge. It remains unresolved to what extent transcriptomic signatures of metabolic dysregulation and T2D can be observed in easily accessible tissues such as blood. Additionally, large-scale human studies are required to further our understanding of the putative inflammatory component of insulin resistance and T2D.
17p
vibransone
28-03-2024
3
2
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Genome-wide association studies (GWAS) have identified more than 100 genetic loci associated with type 2 diabetes (T2D). However, the underlying biological mechanisms for many of these associations remain unknown. GWAS signals close to the glucokinase regulatory protein gene (GCKR) have been reported for lipid and glucose metabolism traits and the risk of T2D.
14p
vioraclene
31-03-2024
2
2
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Skeletal muscle is one of the primary tissues involved in the development of type 2 diabetes (T2D). The close association between obesity and T2D makes it difficult to isolate specific effects attributed to the disease alone. Therefore, here we set out to identify and characterize intrinsic properties of myocytes, associated independently with T2D or obesity.
12p
vioraclene
31-03-2024
2
1
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Worldwide, over 350 million people are chronically infected with the hepatitis B virus (HBV) and are at increased risk of developing progressive liver diseases. The confinement of HBV replication to the liver, which also acts as the central hub for metabolic and nutritional regulation, emphasizes the interlinked nature of host metabolism and the disease.
13p
vioraclene
31-03-2024
6
2
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The liver X receptors (LXRs, NR1H2 and NR1H3) and peroxisome proliferator-activated receptor gamma (PPARG, NR1C3) nuclear receptor transcription factors (TFs) are master regulators of energy homeostasis. Intriguingly, recent studies suggest that these metabolic regulators also impact tumor cell proliferation.
16p
vioraclene
31-03-2024
5
2
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Epidemiological and animal studies have reported that prenatal nicotine exposure (PNE) leads to obesity and type-2 diabetes in offspring. Central leptin-melanocortin signaling via hypothalamic arcuate proopiomelanocortin (POMC) neurons is crucial for the regulation of energy and glucose balance.
27p
vioraclene
31-03-2024
8
2
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