![](images/graphics/blank.gif)
Metabolomic analysis
-
The genetic regulation of metabolic phenotypes (i.e., metabotypes) in type 2 diabetes mellitus occurs through complex organ-specific cellular mechanisms and networks contributing to impaired insulin secretion and insulin resistance. Genome-wide gene expression profiling systems can dissect the genetic contributions to metabolome and transcriptome regulations.
15p
vioraclene
31-03-2024
4
2
Download
-
Spatial multi-omic studies have emerged as a promising approach to comprehensively analyze cells in tissues, enabling the joint analysis of multiple data modalities like transcriptome, epigenome, proteome, and metabolome in parallel or even the same tissue section. This review focuses on the recent advancements in spatial multi-omics technologies, including novel data modalities and computational approaches.
17p
vicwell
29-02-2024
5
2
Download
-
Ebook "Advancements of mass spectrometry in biomedical research" explores the use of mass spectrometry for biomedical applications. Chapters focus on specific therapeutic areas such as oncology, infectious disease, and psychiatry. Additional chapters focus on methodology, technologies and instrumentation, as well as on analysis of protein-protein interactions, protein quantitation, and protein post-translational modifications. Various omics fields such as proteomics, metabolomics, glycomics, lipidomics, and adductomics are also covered.
601p
nhanphanguyet
28-01-2024
2
2
Download
-
Part 2 book "Comprehensive analysis of parasite biology" includes content: Methods to investigate metabolic systems in trypanosoma; the role of metabolomics in antiparasitic drug discovery; the importance of targeting lipid metabolism in parasites for drug discovery; carbon metabolism of plasmodium falciparum; mathematical modeling and omic data integration to understand dynamic adaptation of apicomplexan parasites and identify pharmaceutical targets; ... and other contents.
255p
muasambanhan03
02-01-2024
7
2
Download
-
Part 1 book "Sturkie's avian physiology" includes content: The importance of avian physiology; avian genomics; transcriptomic analysis of physiological systems; avian proteomics; avian metabolomics; mitochondrial physiology—sturkie's book chapter; evolution of birds; domestication of poultry; the avian somatosensory system - a comparative view; avian vision; avian hearing; chemesthesis and olfaction; taste in birds; avian nociception and pain,... and other contents.
791p
muasambanhan03
02-01-2024
9
2
Download
-
Prostate cancer is a common solid tumor that affects a significant number of men worldwide. Conventional androgen deprivation therapy (ADT) increases the risk of developing castration-resistant prostate cancer (CRPC).
16p
vileonardodavinci
23-12-2023
4
2
Download
-
Part 1 of ebook "Metabolomics tools for natural product discovery: Methods and protocols" presents the following content: bryophytes - liverworts, mosses, and hornworts - extraction and isolation procedures; plant tissue extraction for metabolomics; detection of polar metabolites through the use of gas chromatography–mass spectrometry; metabolite analysis of biological fluids and tissues by proton nuclear magnetic resonance spectroscopy;...
155p
dieptieuung
14-07-2023
4
1
Download
-
In the last decade, the consumption trend of organic food has increased dramatically worldwide. However, the lack of reliable chemical markers to discriminate between organic and conventional products makes this market susceptible to food fraud in products labeled as “organic”.
11p
viginny
23-12-2022
7
3
Download
-
Precision medicine has spurred new innovations in molecular pathology leading to recent advances in the analysis of exhaled breath as a non-invasive diagnostic tool. Volatile organic compounds (VOCs) detected in exhaled breath have the potential to reveal a wealth of chemical and metabolomic information.
13p
viginny
23-12-2022
9
2
Download
-
Recent advances in metabolomics have enabled larger proportions of the human metabolome to be analyzed quantitatively. However, this usually requires the use of several chromatographic methods coupled to mass spectrometry to cover the wide range of polarity, acidity/basicity and concentration of metabolites.
11p
viginny
23-12-2022
10
4
Download
-
Pathophysiology of transformation of inflammatory lesions in chronic pancreatitis (CP) to pancreatic ductal adenocarcinoma (PDAC) is not clear. Methods: We conducted a systematic review, meta-analysis of circulating metabolites, integrated this data with transcriptome analysis of human pancreatic tissues and validated using immunohistochemistry. Our aim was to establish biomarker signatures for early malignant transformation in patients with underlying CP and identify therapeutic targets.
13p
vikolindagrabar
27-07-2022
9
3
Download
-
In critically ill patients, glucose control with insulin mandates time– and blood–consuming glucose monitoring. Blood glucose level fluctuations are accompanied by metabolomic changes that alter the composition of volatile organic compounds (VOC), which are detectable in exhaled breath.
9p
viisaacnewton
26-04-2022
6
1
Download
-
The application of non-targeted NMR methods combined with ICP-AES quantification provided an efficient strategy for detecting residual heavy metals within plant tissues and soil. Importantly, non-targeted metabolomic analysis helped to reveal the relationships between metabolites distribution in hemp tissues and the sequestered metals.
10p
thebadguys
15-01-2022
5
0
Download
-
Recent studies highlight the role of metabolites in immune diseases, but it remains unknown how much of this effect is driven by genetic and nongenetic host factors.
22p
viarchimedes
26-01-2022
11
0
Download
-
The bast fiber crop ramie can be used as high-quality forage resources, especially in tropical or subtropical region where there is lack of high-quality protein feed. Hongxuan No.1 (HX_1) is a unique ramie variety with a light reddish brown leaf color, which is obviously different from elite cultivar, Zhongzhu No.1 (ZZ_1, green leaf). While, the regulatory mechanism of color difference or secondary metaboliates synthesis between these two varieties have not been studied.
15p
vitzuyu2711
29-09-2021
10
2
Download
-
We present results from a computational analysis developed to integrate transcriptome and metabolomic data in order to explore the heat stress response in the liver of the modern broiler chicken. Heat stress is a significant cause of productivity loss in the poultry industry, both in terms of increased livestock morbidity and its negative influence on average feed efficiency.
16p
visilicon2711
20-08-2021
13
1
Download
-
Many genome-wide association studies have detected genomic regions associated with traits, yet understanding the functional causes of association often remains elusive. Utilizing systems approaches and focusing on intermediate molecular phenotypes might facilitate biologic understanding.
16p
visilicon2711
20-08-2021
9
1
Download
-
Compensatory growth refers to the phenomenon in which organisms grow faster after the improvement of an adverse environment and is thought to be an adaptive evolution to cope with the alleviation of the hostile environment. Many fish have the capacity for compensatory growth, but the underlying cellular mechanisms remain unclear.
13p
viansan2711
30-07-2021
8
1
Download
-
Flammulina velutipes has been recognized as a useful basidiomycete with nutritional and medicinal values. Ergosterol, one of the main sterols of F. velutipes is an important precursor of novel anticancer and anti-HIV drugs.
12p
viansan2711
30-07-2021
9
1
Download
-
Candida albicans is an opportunistic pathogenic yeast, which could become pathogenic in various stressful environmental factors including the spaceflight environment. In this study, we aim to explore the phenotypic changes and possible mechanisms of C. albicans after exposure to spaceflight conditions.
9p
vijeeni2711
24-07-2021
11
0
Download
CHỦ ĐỀ BẠN MUỐN TÌM
![](images/graphics/blank.gif)