Microgravity conditions

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Summary of Biotechnology doctoral thesis: Evaluation of changes in proliferation and cytoskeletal structure of human umbilical cord mesenchymal stem cells under simulated microgravity

The aim of this thesis was to gain an understanding of how the simulated microgravity condition affects the development of hucMSC by investigating the changes in cell morphology, proliferation and cytoskeleton structure of hucMSCs under in vitro condition.

27p beloveinhouse01 15-08-2021 16 4 Download

Evaluating the effects of simulated microgravity on mouse fibroblast

The present study investigated how mouse fibroblasts changed under microgravity (SMG) conditions (< 10-3 G) simulated by 3D clinostat. Results showed that SMG condition markedly reduced the proliferation of mouse fibroblasts, significantly reducing the nuclear area and intensity. Compared to the control group, the mouse fibroblasts ratio of the SMG group was higher in the G0/G1 phase but lower in the S phase and G2/M phase...

6p nguaconbaynhay10 20-02-2021 6 2 Download

Sonic hedgehog promotes chondrogenesis of rabbit bone marrow stem cells in a rotary cell culture system

Sonic hedgehog (Shh) is an important signalling protein involved in the induction of early cartilaginous differentiation. Herein, we demonstrate that Shh markedly induces chondrogenesis of rabbit bone marrow stromal cells (BMSCs) under microgravity conditions, and promotes cartilage regeneration.

12p viwyoming2711 16-12-2020 13 0 Download
Flight mechanics experiment onboard nasa’s zero gravity aircraft

This paper presents a method to promote STEM (Science, Technology, Engineering, and Mathematics) education through participation in a reduced gravity program with NASA (National Aeronautics and Space Administration). Microgravity programs with NASA provide students with a unique opportunity to conduct scientific research with innovative and creative solutions through hands-on experimental design and testing in reduced gravity conditions.

9p guestgreat 06-05-2019 21 0 Download
Differential behaviour of normal, transformed and Fanconi’s anemia lymphoblastoid cells to modeled microgravity

Cuccarolo et al. Journal of Biomedical Science 2010, 17:63 http://www.jbiomedsci.com/content/17/1/63 Whether microgravity might influence tumour growth and carcinogenesis is still an open issue. It is not clear also if and how normal and transformed cells are differently solicited by microgravity. The present study was designed to verify this issue. Methods: Two normal, LB and HSC93, and two transformed, Jurkat and 1310, lymphoblast cell lines were used as representative for the two conditions.

10p toshiba23 18-11-2011 50 1 Download