Mild reaction conditions
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Ebook "Polyoxomolybdates as green catalysts for aerobic oxidation" describes the importance of the selective oxidation of alcohols and advantages of heterogeneous catalysts over conventional catalysts, use of environmentally benign oxidants, and the design of selective catalysts by tailoring of polyoxometalates at the molecular level. Chapter 2 describes synthesis, characterization 11-molybdophosphate based supported materials and their use as heterogeneous catalysts for oxidation of alcohols with molecular oxygen under solvent free mild reaction condition.
63p tudohanhtau1006 29-03-2024 2 1 Download
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The synthesized complexes have also been explored for forensic applications as fingerprint developing dyes. Apart from the excellent photoluminescent properties and forensic applications of the synthesized compounds, the scope of the work includes mild reaction conditions and better yield with easy of one pot synthesis by using readily available salicylaldehydes/2-hydroxy-1-napthaldehyde, cylohexyl-1,2-diamine and zinc acetate.
9p viberbers 09-08-2023 9 3 Download
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Reactions of isocyanides with thioacids in water proceeded smoothly at room temperature and in neutral conditions to afford thioformylamide and thioformamide derivatives in high yields. The reaction proceeded smoothly and cleanly under mild conditions and no side reactions were observed.
8p langthannam 29-12-2021 16 0 Download
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Esterification of organic acids with alcohols under mild conditions in high yields using graphite oxide, a readily available and inexpensive material, as an effective reagent is described. Esters are a class of compounds widely distributed in nature. Esters encompass a large family of organic compounds with broad applications in medicine, biology, chemistry, and industry as plasticizers, solvents, perfumes, and flavor chemicals and also as precursors for a gamut of pharmaceuticals, agrochemicals, and other fine chemicals.
6p langthannam 29-12-2021 12 0 Download
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A facile one-pot synthesis of novel oxindole derivatives bearing benzothiazolylmethyl-2-thioxothiazolidin-4- one was accomplished via one-pot reaction of 5-oxoindolinylidene rhodanine-3-acetic acid derivatives, 2-aminothiophenol, and triphenyl phosphite in the presence of tetrabutylammonium bromide (TBAB) and nano silica-bonded 5-n-propyloctahydro-pyrimido[1,2-a]azepinium chloride (NSB-DBU) as heterogeneous reusable nanocatalyst. The target compounds were obtained in excellent yields (85%–92%) and short reaction times under fairly mild reaction conditions.
9p langthannam 29-12-2021 13 1 Download
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A highly efficient and environmentally benign protocol for the synthesis of 2-amino-7-hydroxy-4-aryl-4H-chromene-3-carbonitrile derivatives in good to high yields (77%–97%) by one-pot three-component coupling reaction of aromatic aldehydes, malononitrile, and resorcinol under reflux condition was developed in aqueous media using ZnO nanoparticles that were prepared in the presence of mulberry leaf extract under mild conditions.
9p langthannam 29-12-2021 10 1 Download
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The three-component reaction of benzoic acid derivatives, (N -isocyanimino)triphenylphosphorane, and trichloroacetyl isocyanate in a 1:1:1 ratio in CH3 CN occurred at room temperature, and the 5-aryl-N -(trichloroacetyl)- 1,3,4-oxadiazole-2-carboxamide derivatives produced were formed in high yields. The reaction proceeded smoothly and cleanly under mild reaction conditions and no side reactions were observed. The structures of the products were confirmed by IR, 1 H NMR, 13 C NMR, mass spectroscopy, and elemental analysis.
6p langthannam 29-12-2021 5 0 Download
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The compounds were characterized by spectroscopic and elemental analyses. The synthesized NHC–Ag(I) complexes (3a–c) were tested as catalysts for the catalytic threecomponent coupling reaction of aldehyde, alkyne, and amine to propargylamines in various solvents. All complexes were active catalysts for catalytic three-component coupling reactions with good yields under neat and mild conditions (after 4 h, yields of up to 94%).
7p langthannam 29-12-2021 6 0 Download
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Aliphatic nitroalkanes with different functional groups were synthesized from the Michael addition reactions of active methylene compounds 2 and nitrovinyl arenes 1 in high yields. The synthesized Michael adducts were subjected to intramolecular cyclization to give heteroaryl substituted γ -lactams in good to high yields under mild reaction conditions.
7p tudichquannguyet 29-11-2021 8 0 Download
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Nickel ferrite magnetic nanoparticles (NiFe2O4MNPs) were prepared via the autocombustion assisted solgel method. The efficient catalyst was investigated by FT-IR, XRD, ICP, SEM, and TEM techniques. A one-pot, three-component reaction is reported for the synthesis of substituted 4H -chromenes in the presence of NiFe2O4 MNPs as a reusable catalyst in a green solvent at 40◦C under clean, efficient, and mild conditions. Furthermore, selected products were characterized by FT-IR, 1H NMR, and 13C NMR. The single-crystal X-ray analysis of product 4u was also conclusively confirmed.
16p tudichquannguyet 29-11-2021 15 1 Download
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In this study, encapsulation processes of cetyltrimethylammonium bromide (CTAB) or sodium dodecyl sulfate (SDS) monomers into the cavity of β -cyclodextrin (β -CD) were applied to synthesize mono- and bis (indolyl)methylmalononitrile derivatives by a one-pot three-component reaction of an aldehyde, malononitrile, and indole in an aqueous solution. These two inclusion complexes proved to be superior to CTAB or SDS individually, as cationic or anionic surfactants, respectively, for accessing high yields of pure products within shorter reaction times.
9p tudichquannguyet 29-11-2021 6 1 Download
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A facile synthesis of piperidinium 3,3’-(arylmethylene) bis (2-hydroxynaphthalene-1,4-dione) analogs as organic salts is described by the one-pot pseudo-four-component reaction between 2-hydroxy-1,4-naphthoquinone, aromatic aldehydes, and piperidine. The single-crystal X-ray diffraction analysis of these systems confirms that the stabilized predominant interactions are N-H...O and O-H...O hydrogen bonds.
10p tudichquannguyet 29-11-2021 6 0 Download
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An efficient synthetic route has been described for the alkylation of 1H -indole, 1H -benzimidazole, and 1H -benzotriazole. This approach features the alkylation of heteroaromatics through in situ generated enones from ketonic Mannich bases under metal-free conditions. A series of alkylated heteroaromatics have been synthesized via the K10 catalyzed alkylation reactions of these heteroaromatics with a variety of ketonic Mannich bases.
13p tudichquannguyet 29-11-2021 15 1 Download
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An efficient and facile method has been developed for the synthesis of alkyl bromides from various alcohols under mild conditions using a triphenylphosphine (PPh3)/1,2-dibromotetrachloroethane (DBTCE) complex in excellent yields and very short time (5 min). This method can also be applied for the transformation of chiral alcohols to their corresponding bromides in very high enantiomeric excess. The PPh3 /DBTCE complex is also successfully applied to ring-opening reactions of cyclic ethers in mild conditions.
7p tudichquannguyet 29-11-2021 4 1 Download
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1,2-Ethylene-bis(para-methyl pyridinium) dichromate, (C14H18N2)[Cr2O7], is used as a new oxidizing agent in conversion of some alcohols to their corresponding carbonyl compounds in CH3 CN solvent and also under solvent-free conditions. In both procedures, high conversion percentages are observed. However, a much shorter reaction time is achieved in solvent-free conditions. For allylic alcohols, the C=C bond is not oxidized and the examined saturated alcohol in this work (i.e. cyclo-hexanol) remains intact, which illustrates the mild nature of reagent used.
12p tudichquannguyet 29-11-2021 7 1 Download
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A new heterogeneous acid catalyst based on a natural resource, Tunisian clay (Clay-H0.5), has been prepared and characterized by FT-IR, FE-SEM, and powder X-ray diffraction (XRD), as well as chemical composition, cation exchange capacity, specific surface area, and pore volume. Acid treatment for 0.5 h enlarged the surface area from 78.24 to 186.10 m2/g and pore volume (PV) from 0.186 to 0.281 cm3/g. The catalytic activity of this material was investigated in ketalization reaction under mild solvent-free conditions. This achieved up to 92% isolated yield for only 10 wt.% of the catalyst.
17p tudichquannguyet 29-11-2021 17 2 Download
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This study demonstrated the kinetics of nucleophilic substitution reactions of butyl methyl chlorophosphate (2) with X-anilines (XC6H4NH2) and deuterated X-anilines (XC6H4ND2) in MeCN at 55.0 ± 0.1°C together with the general optimized method for the synthesis of 2 under mild conditions. Different spectroscopic characterizations revealed the formation of 2 with high purity. The free energy relationship with the substituents X in the anilines exhibited biphasic concavity upwards with a break point at X = H, which induced large negative ρX and small positive βX values.
16p tudichquannguyet 29-11-2021 8 1 Download
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A catechol-based benzoxazine copolymer is reported via a new approach using an oxazine-thiol reaction. The main chain benzoxazine precursor was obtained via the classic benzoxazine synthesis methodology using the raw chemicals catechol, formaldehyde, and 4,7,10-trioxa-1,13-tridecanediamine. The countercomponent was synthesized from poly(ethylene glycol) methyl ether via the Fischer esterification reaction. The obtained reactive catechol-based benzoxazine was then reacted in mild conditions with polymeric thiol precursor to obtain a copolymer structure.
14p tudichquannguyet 29-11-2021 8 1 Download
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In this study, nine different C-2 aroyl imidazole derivatives were synthesized in a one pot reaction with two steps, and the reduction reactions of these derivatives with NaBH4 were carried out under mild conditions. Substitution reaction of obtained imidazo methanol derivatives with chloroacetylchloride reagent and ring reaction of substitution products were investigated. It was determined that 1,4-imidazoxazinone derivative was obtained as a result of the cyclization reaction.
42p tudichquannguyet 29-11-2021 6 1 Download
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The various organic acids have screened; like gallic acid, 4-hydroxy benzoic acid, 4-amino benzoic acid, phenylacetic acid, chloroacetic acid, sulfosalicylic acid, sulfanilic acid, chloro benzoic acid, phthalic acid, salicylic acid, cinnamic acid, hippuric acid, 1- naphthyl acetic acid, o-amino benzoic acid, p-TSA, succinic acid, malic acid, and among them sulfanilic acid is a suitable catalyst. The reaction condition was optimized with respect to the solvent, the amount of catalyst as well as the variation of the ketone, aldehyde, and amine substrates.
13p cothumenhmong11 06-05-2021 15 2 Download