![](images/graphics/blank.gif)
miRNA microarray
-
Ebook "MicroRNA detection and pathological functions" summarizes microRNA (miRNA) biology in a variety of pathological processes, emphasizing the significant potential applications of miRNA in diagnostics and prognostics, as well as novel drug targets. The conventional techniques used for miRNA detection including standard PCR, Northern blotting, microarray and clone methods are addressed.
108p
nhanphanguyet
28-01-2024
3
2
Download
-
"Nghiên cứu xác định một số micrornas tiềm năng liên quan đến u thần kinh đệm (Glioma)" nghiên cứu dữ liệu microarray từ GEO và các công cụ thống kê sinh học được dùng để đánh giá mức độ biểu hiện miRNAs liên quan đến Glioma ở bệnh nhân châu Á. Kết quả cho thấy miR-6780a-5p và miR-6754-3p đóng vai trò như một miRNA ức chế khối u và giá trị AUC của hai phân tử này nằm trong khoảng 84%-88%. Mời các bạn cùng tham khảo!
6p
lieuyeuyeu18
23-12-2022
9
2
Download
-
More and more studies have proven that circular RNAs (circRNAs) play vital roles in cancer development via sponging miRNAs. However, the expression pattern of competing endogenous RNA (ceRNA) in lung adenocarcinoma (LUAD) remains largely unclear.
10p
vimahuateng
26-11-2021
6
2
Download
-
Ovarian cancer (OC) is a gynecological malignancy with the highest mortality rate. Cisplatin (DDP) based chemotherapy is a standard strategy for ovarian cancer. Despite good response rates for initial chemotherapy, almost 80% of the patients treated with DDP based chemotherapy will experience recurrence due to drug-resistant, which will ultimately result in fatality.
13p
vianrose2711
27-04-2021
3
1
Download
-
It has been found that microRNAs (miRNAs) play important roles in the regulation of tooth development, and most likely increase the complexity of the genetic network, thus lead to greater complexity of teeth. But there has been no research about the key microRNAs associated with tooth morphogenesis based on miRNAs expression profiles.
12p
viwyoming2711
16-12-2020
12
1
Download
-
Missing values are commonly present in microarray data profiles. Instead of discarding genes or samples with incomplete expression level, missing values need to be properly imputed for accurate data analysis. The imputation methods can be roughly categorized as expression level-based and domain knowledge-based.
8p
vioklahoma2711
19-11-2020
12
2
Download
-
MicroRNAs (miRNAs) show differential expression across breast cancer subtypes and have both oncogenic and tumor-suppressive roles. Numerous microarray studies reported different expression patterns of miRNAs in breast cancers and found clinical interest for several miRNAs but often with contradictory results.
14p
viamsterdam
18-09-2020
9
0
Download
-
Mounting evidence suggests that miRNAs have major functions in tumor pathogenesis, and this study aimed to identify the candidate miRNA and investigate its role in nasopharyngeal carcinoma (NPC).
12p
viamsterdam
18-09-2020
12
1
Download
-
The aim of this study was to gain further investigation of non-small cell lung cancer (NSCLC) tumorigenesis and identify biomarkers for clinical management of patients through comprehensive bioinformatics analysis.
10p
viorochimaru2711
01-06-2020
14
1
Download
-
microRNAs (miRNAs) are endogenous small (~21 nucleotide) single-stranded non-coding RNAs that typically function by guiding cleavage of target genes. To find the miRNAs that may be involved in dark-induced leaf senescence, we identified miRNAs by microarray platform using Arabidopsis thaliana leaves from both whole darkened plants (DPs) and individually darkened leaves (IDLs).
12p
vihashirama2711
21-05-2020
11
1
Download
-
To analyze the miRNAs expression profiling between acquired middle ear cholesteatoma and normal skin, and to identify several novel miRNAs which may be involved in the etiopathogenesis of middle ear cholesteatoma.
8p
vihasaki2711
12-11-2019
11
1
Download
-
We aimed to analyze the in vitro and in vivo effects of miRNA-19b/20a/92a on gastric cancer stem cells (GCSCs) and the related mechanism. GCSCs were cultured until adherence and differentiation, and subjected to miRNA microarray analysis to find and to verify miRNA deletion. Cells stably expressing lentivirus carrying miRNA-19b/20a/92a were constructed by transfection.
9p
vinasaki2711
12-11-2019
16
1
Download
-
Breast cancer is the most common cancer among women and the molecular pathways that play main roles in breast cancer regulation are still not completely understood. MicroRNAs (miRNAs) and transcription factors (TFs) are important regulators of gene expression.
17p
nutifooddau
27-01-2019
13
2
Download
-
The mechanisms whereby hepatic fibrosis develops in chronic liver diseases remain incompletely defined. Here, we sought to examine whether micro-RNA (miRNA) became dysregulated in dimethylnitrosamine-induced hepatic fibrosis in rats. Our microarray analysis revealed that the miR-34 family was upregulated along with other miRNAs in liver fibrotic tissues. Six miRNAs, such as rno-miR-878, were downregulated.
11p
cosis54
05-01-2013
45
4
Download
CHỦ ĐỀ BẠN MUỐN TÌM
![](images/graphics/blank.gif)