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Molecular data sets
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Ebook "Cell–Cell interactions: Methods and protocols" is a versatile collection of readily reproducible cell-cell interaction assays for uncovering cellular interactions at the molecular level, both in vitro and in vivo. The protocols cover a diverse set of cell-cell interaction models in both normal and pathological states, are readily adaptable to nearly any cell type and organ system, and include primary data and outcome analysis.
306p
dongmelo
27-05-2024
3
3
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Patterns in expression data conserved across multiple independent disease studies are likely to represent important molecular events underlying the disease. We present the INSPIRE method to infer modules of co-expressed genes and the dependencies among the modules from multiple expression datasets that may contain different sets of genes.
31p
vioraclene
31-03-2024
4
2
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The most recent research projects in scientifc feld of eutherian comparative genomics included intentions to sequence every extant eutherian species genome in foreseeable future, so that future revisions and updates of eutherian gene data sets were expected.
4p
vihagrid
30-01-2023
11
3
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This study aimed to identify potential biomarkers, by means of bioinformatics, affecting the occurrence and development of septic shock. Methods: Download GSE131761 septic shock data set from NCBI geo database, including 33 control samples and 81 septic shock samples. GSE131761 and sequencing data were used to identify and analyze differentially expressed genes in septic shock patients and normal subjects.
13p
vihagrid
30-01-2023
8
3
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The study "Genetic analysis of African swine fever virus based on major genes encoding p72, p54 and p30" was set out to characterize African swine fever virus genotypes from 20 farms in 10 provinces, which occurred ASF outbreaks in 2019 and 2020. The results are expected to contribute sequence data for molecular epidemiology studies and provide further understanding of ASF disease patterns in Southern Vietnam.
8p
tieuvulinhhoa
22-09-2022
7
2
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This study aims to construct a new prognostic gene signature in survival prediction and risk stratification for patients with Head and neck squamous cell carcinoma (HNSCC). The transcriptome profiling data and hallmark gene sets in the Molecular Signatures Database was used to explore the cancer hallmarks most relevant to the prognosis of HNSCC patients.
19p
vikolindagrabar
27-07-2022
7
2
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The phylogenetic relationship of 83 taxa of Santalaceae s.l. was reconstructed based on the molecular data sets including the nuclear ribosomal (small and large subunit rDNA) and the chloroplast rbcL, matK, and trnL-F regions. The Maximum likelihood (ML) and Bayesian inference (BI) methods were used to build the phylogenetic trees.
8p
viellenkullman
13-05-2022
6
1
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Exploring the phylogenetic relationships between taxa provides important information for science. The phylogenetic study of Macrosolen was conducted based on molecular data sets of 27 taxa with five DNA regions including chloroplast rbcL, matK, and trnL-F and nuclear ribosomal (small subunit rDNA and large subunit rDNA) regions to reconstruct the phylogenetic relationship of Macrosolen.
7p
viginnirometty
04-05-2022
17
1
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Autism spectrum disorder (ASD) is a common neurodevelopmental disorder that tends to co-occur with other diseases, including asthma, inflammatory bowel disease, infections, cerebral palsy, dilated cardiomyopathy, muscular dystrophy, and schizophrenia. However, the molecular basis of this co-occurrence, and whether it is due to a shared component that influences both pathophysiology and environmental triggering of illness, has not been elucidated.
19p
viaristotle
29-01-2022
32
0
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The compounds were characterized by analytical and spectral methods. In addition, X-ray diffraction was performed to characterize and obtain detailed information about the structure of 3. The fully optimized geometries of compounds 3 and 4 were calculated at different basis sets by using the Gaussian09 (G09) software to investigate their 3D geometries and electronic structures. Comparisons between the calculated and experimental data including molecular structures, fundamental vibrational modes, and electronic properties were made.
17p
langthannam
29-12-2021
12
0
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The molecular structure of bis(2‒isobutyrylamidophenyl)amine (H3 LNNN) has been determined from single‒crystal X-ray diffraction data. The crystal packing of H3 LNNN is governed by the N–H⋯O and C–H⋯O hydrogen-bonding and C–H⋯π stacking interactions between the vicinal molecules. The intermolecular interactions in the crystal structure of H3 LNNN have been also examined via Hirshfeld surface analysis and fingerprint plots. The Hirshfeld surface analysis showed that the important role of N–H⋯O and C– H⋯π interactions in the solid‒state structure of H3 LNNN.
33p
langthannam
29-12-2021
7
0
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Comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) of three-dimensional quantitative structure–activity relationship (3D-QSAR) models were conducted using 36 aromatic compound congeners as the training set and eight aromatic compound congeners as the test set. Logarithms of experimental bioconcentration data (logBCF) were used as dependent variables and the physicochemical properties of the aromatic compound congeners were used as independent variables.
21p
tudichquannguyet
29-11-2021
13
1
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In this review, important parameters used in evaluation of plant resistance ability against salinity stress are discussed, which highlights the necessity to obtain multi-sets of biological data ranging from analyses of morphological alterations to physiological, biochemical and molecular responses, as well as by performing -omics studies to find out network of salinity-responsive pathways. Literature review also demonstrates that the relevance of salinity condition setup in terms of concentration and duration is required in experimental design.
16p
spiritedaway36
25-11-2021
14
1
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Recently, a number of studies have been conducted to investigate how plants respond to stress at the cellular molecular level by measuring gene expression profiles over time. As a result, a set of time-series gene expression data for the stress response are available in databases.
13p
viansan2711
30-07-2021
18
3
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The consensus on how to choose a reference gene for serum or plasma miRNA expression qPCR studies has not been reached and none of the potential candidates have yet been convincingly validated. We proposed a new in silico approach of finding a suitable reference for human, circulating miRNAs and identified a new set of endogenous reference miRNA based on miRNA profiling experiments from Gene Expression Omnibus.
15p
vijeeni2711
24-07-2021
7
0
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The eutherian fibroblast growth factors were implicated as key regulators in developmental processes. However, there were major disagreements in descriptions of comprehensive eutherian fibroblast growth factors gene data sets including either 18 or 22 homologues.
10p
vijeeni2711
30-06-2021
17
1
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Analysis of global gene expression by DNA microarrays is widely used in experimental molecular biology. However, the complexity of such high-dimensional data sets makes it difficult to fully understand the underlying biological features present in the data.
15p
viwyoming2711
16-12-2020
14
1
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Gaining biological insights into molecular responses to treatments or diseases from omics data can be accomplished by gene set or pathway enrichment methods. A plethora of diferent tools and algorithms have been developed so far. Among those, the gene set enrichment analysis (GSEA) proved to control both type I and II errors well.
13p
viwyoming2711
16-12-2020
16
1
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Molecular data, e.g. arising from microarray technology, is often used for predicting survival probabilities of patients. For multivariate risk prediction models on such high-dimensional data, there are established techniques that combine parameter estimation and variable selection.
16p
vikentucky2711
26-11-2020
8
0
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Sharing sets of chemical data (e.g., chemical properties, docking scores, etc.) among collaborators with diverse skill sets is a common task in computer-aided drug design and medicinal chemistry.
7p
vikentucky2711
26-11-2020
10
0
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