![](images/graphics/blank.gif)
Molecular diagnosis and prognosis
-
The number of druggable tumor-specific molecular aberrations has grown substantially in the past decade, with a significant survival benefit obtained from biomarker matching therapies in several cancer types. Molecular pathology has therefore become fundamental not only to inform on tumor diagnosis and prognosis but also to drive therapeutic decisions in daily practice.
19p
vibransone
28-03-2024
2
2
Download
-
Part 1 book "Tumors in domestic animals" includes content: An overview of molecular cancer pathogenesis, prognosis, and diagnosis; trimming tumors for diagnosis and prognosis; immunohistochemistry - fundamentals and applications in oncology; epithelial and melanocytic tumors of the skin; mesenchymal tumors of the skin and soft tissues, mast cell tumors, tumors of the hemolymphatic system, canine and feline histiocytic diseases,... and other contents.
474p
muasambanhan05
22-01-2024
3
2
Download
-
Ebook "Bioinformatics for diagnosis, prognosis and treatment of complex diseases" introduces the bioinformatics tools, databases and strategies for the translational research, focuses on the biomarker discovery based on integrative data analysis and systems biological network reconstruction. With the coming of personal genomics era, the biomedical data will be accumulated fast and then it will become reality for the personalized and accurate diagnosis, prognosis and treatment of complex diseases.
219p
lamquandat
28-12-2023
10
2
Download
-
Previous studies on cancer of unknown primary (CUP) mainly focus on treatment and prognosis in western populations and lacked clinical evaluation of different IHC markers, so this study aimed to evaluate characteristics of CUP and recommend a diagnostic strategy from a single center in China.
10p
vialfrednobel
23-12-2023
2
2
Download
-
Effective identification and development of new molecular methods for the diagnosis, treatment and prognosis of lung adenocarcinoma (LUAD) remains an urgent clinical need. DNA methylation patterns at cytosine bases in the genome are closely related to gene expression, and abnormal DNA methylation is frequently observed in various cancers.
12p
vioracle
29-09-2023
4
2
Download
-
Non-small cell lung cancer (NSCLC) is the most common type of lung cancer and has a poor prognosis. Identifying biomarkers based on molecular mechanisms is critical for early diagnosis, timely treatment, and improved prognosis of lung cancer. MALAT1 has been reported to have overexpressed and tumor-promoting functions in NSCLC.
14p
vioracle
29-09-2023
6
2
Download
-
Leukemia is the most common type of cancer in pediatrics. Genomic mutations contribute towards the molecular mechanism of disease progression and also helps in diagnosis and prognosis. This is the first scientific mutational exploration in whole exome of pediatric leukemia patients from a cancer-prone endogamous Mizo tribal population, Northeast India.
9p
vihagrid
30-01-2023
7
3
Download
-
Gastric cancer (GC) is a primary reason for cancer death in the world. At present, GC has become a public health issue urgently to be solved to. Prediction of prognosis is critical to the development of clinical treatment regimens. This work aimed to construct the stable gene set for guiding GC diagnosis and treatment in clinic.
12p
vimahuateng
26-11-2021
9
0
Download
-
The KRT5 p.E477K was strong associated with the very severe or lethal of generalized severe EBS (GS-EBS), characterized by the severe symptoms at birth, improving with age and evolution to palmoplantar keratoderma and nail dysplasia. Our finding will aid the molecular diagnosis, prognosis prediction of the patient with GS-EBS due to p.E477K and significant genetic counselling the family concerning the recurrence risk for future pregnancies.
6p
spiritedaway36
25-11-2021
13
1
Download
-
Due to tumor heterogeneity, the diagnosis, treatment, and prognosis of patients with lung squamous cell carcinoma (LUSC) are difficult. DNA methylation is an important regulator of gene expression, which may help the diagnosis and therapy of patients with LUSC.
12p
vianrose2711
27-04-2021
9
1
Download
-
Human papillomavirus DNA detection in head and neck squamous cell carcinoma has been linked to improved patient prognosis. The main aims of the study was to test the hypotheses that HPV16 E6/E7 oncogene and p53 function within tumours were associated with the widely reported improved patient survival and prognosis in head and neck cancer.
11p
vinaypyidaw2711
26-08-2020
6
2
Download
-
The prognosis is very poor for lung cancer patients with bone metastasis. Unfortunately, a suitable method has yet to become available for the early diagnosis of bone metastasis in lung cancer patients.
11p
vimanila2711
25-06-2020
24
1
Download
-
Clear cell renal cell carcinoma (ccRCC) is the most common subtype among renal cancer and is associated with poor prognosis if metastasized. Up to one third of patients with local disease at diagnosis will develop metastasis after nephrectomy, and there is a need for new molecular markers to identify patients with high risk of tumor progression.
16p
viputrajaya2711
22-06-2020
3
0
Download
-
Pancreatic cancer is a devastating disease with a dismal prognosis. Despite profound medical advances in systemic therapies for other types of aggressive tumours during recent years, a diagnosis of pancreatic cancer is still often synonymous with a fatal outcome.
7p
viorochimaru2711
01-06-2020
13
1
Download
-
There is still a great unmet medical need concerning diagnosis and treatment of breast cancer which could be addressed by utilizing specific molecular targets. Tumor-associated MUC1 is expressed on over 90 % of all breast cancer entities and differs strongly from its physiological form on epithelial cells, therefore presenting a unique target for breast cancer diagnosis and antibody-mediated immune therapy.
11p
vinasaki2711
12-11-2019
5
2
Download
-
(bq) part 1 book "molecular diagnostics for dermatology" presents the following contents: introduction, basics of nucleic acids and molecular biology, molecular methods; risk assessment, diagnosis, and prognosis - using molecular tools to diagnose melanoma, predict its behavior and evaluate for inheritable forms,...
182p
thangnamvoiva5
14-07-2016
64
2
Download
-
T-cell leukemia is relatively rare malignancy of thymocytes. There are around 20 entities and variants of this disease. Each of them has different characteristics, including pathogenesis, epidemiology, diagnosis, therapeutic approaches, and prognosis. Although T-cell leukemia is relatively rare malignancy, many types of T-cell leukemias still have a very poor prognosis due to rapid progression.
148p
japet75
25-02-2013
37
1
Download
-
Gastric cancer is the second most common cause of cancer-related death in the world. There are no screening tests available for its diagnosis, therefore patients usually presents in late stages, associated with poor prognosis. Currently, many efforts are made toward new advances in the treatment strategies. The book makes an insight into the assessment of premalignant lesions, current management of early gastric cancer, risk and protective factors in gastric carcinogenesis.
304p
phoebe75
19-02-2013
69
7
Download
-
Over the past 20 years, technological advances in molecular biology have proven invaluable to the understanding of the pathogenesis of human cancer. The application of molecular technology to the study of cancer has not only led to advances in tumor diagnosis, but has also provided markers for the assessment of prognosis and disease progression. The aim of Molecular Analysis of Cancer is to provide a comprehensive collection of the most up-to-date techniques for the detection of molecular changes in human cancer.
302p
tom_123
15-11-2012
78
14
Download
-
The potential value of artificial neural networks (ANNs) as a predictor of malignancy has now been widely recognised. The concept of ANNs dates back to the early part of the 20th century; however, their latest resurrection started in earnest in the 1980s when they were applied to many problems in the areas of pattern recognition, control, and optimisation.
212p
echbuon
02-11-2012
100
8
Download
CHỦ ĐỀ BẠN MUỐN TÌM
![](images/graphics/blank.gif)