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Molecular diagnostics
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Long nonconding RNAs (lncRNAs) have been found to be a vital regulatory factor in the development process of human cancer, and could regarded as diagnostic or prognostic biomarkers for human cancers. Here, we aim to confirm the expression and molecular mechanism of RP11-171K16.5 (lnc171) in hepatocellular carcinoma (HCC).
13p
vishanshan
27-06-2024
1
1
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Methylation of the promoters of SHOX2 and RASSF1A (LungMe®) exhibits promise as a potential molecular biomarker for diagnosing lung cancer. This study sought to assess the aberrant methylation of SHOX2 and RASSF1A in broncho-exfoliated cells (BEC) and compare it with conventional cytology, histology examination, immunohistochemistry, and serum tumor markers to evaluate the overall diagnostic efficiency for lung cancer.
14p
vikoch
27-06-2024
3
1
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Colorectal cancer (CRC) is a common malignancy worldwide. MicroRNAs (miRNAs) are important epigenetic alterations that notably impact various physiological and pathological processes by acting as negative regulators of gene expression. Furthermore, they have a vital function in different types of cancers, including CRC.
7p
vikoch
27-06-2024
1
1
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Updating researchers on phenomenal progress in the field of molecular medicine the Encyclopedia of Medical Genomics and Proteomics offers trail-blazing studies and authoritative contributions from more than 400 specialists. Topics include: Molecular diagnostics; Genomics, microbiology, genetics, and pharmacogenetics; Management of infectious, neoplastic, and genetic diseases;...
1391p
vimeyers
29-05-2024
3
2
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Part 2 book "Color atlas of diagnostic microbiology" includes content: Mycobacteria, microbial pahogens isolated and/or inentified by tissue culture of other special methods, antimicrobial susceptibility testing, molecular techniques.
122p
zizaybay1101
30-04-2024
5
2
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Ebook "Molecular markers in mycology: Diagnostics and marker developments" contains a thorough discussion of molecular characterization and detection of different groups of fungi by using PCR-based markers and provides a comprehensive view of the applications and uses of different molecular markers in molecular mycology. It also addresses the recent molecular markers employed to solve the problems of identification and discusses current approaches used in molecular characterization and detection of fungi.
368p
tracanhphuonghoa1007
22-04-2024
1
1
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Ebook "The long and short noncoding RNAs in cancer biology" conveys a comprehensive knowledge of long and short ncRNAs in cancer regulation and their potentials as diagnostic biomarkers and therapeutic targets. Topics covered include the molecular mechanisms of various classes of ncRNAs (with emphasis on long non-coding RNAs and microRNAs) in cancer, the functional roles of ncRNAs in regulating different cancer hallmarks (including proliferation, apoptosis, stem-cell properties, epithelial-mesenchymal transition, metabolism, angiogenesis, tumor-host interactions and therapeutic resistance).
455p
tracanhphuonghoa1007
22-04-2024
4
2
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Ebook "Cancer biology and the nuclear envelope: Recent advances may elucidate past paradoxes" presents a comprehensive overview of the wide range of functions recently identified for NE proteins and their relevance in cancer biology, providing molecular mechanisms and evidence of their value as prognostic and diagnostic markers and suggesting new avenues for the treatment of cancer.
610p
tracanhphuonghoa1007
22-04-2024
2
1
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Part 1 book "Molecular diagnostics - Fundamentals, methods, and clinical applications" includes content: Nucleic acids and proteins; gene expression and epigenetics; nucleic acid extraction methods; resolution and detection of nucleic acids; analysis and characterization of nucleic acids and proteins; nucleic acid amplifi cation; chromosomal structure and chromosomal mutations, gene mutations; DNA sequencing.
280p
muasambanhan10
06-04-2024
2
0
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Part 2 book "Molecular diagnostics - Fundamentals, methods, and clinical applications" includes content: DNA polymorphisms and human identifi cation, detection and identifi cation of microorganisms; molecular detection of inherited diseases, molecular oncology, DNA based tissue typing, quality assurance and quality control in the molecular laboratory.
303p
muasambanhan10
06-04-2024
3
0
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Part 2 book "Pharmaceutical design and development" includes content: Rational design of drugs based on molecular structure, nucleic acid therapies, transgenic animal models, diagnostic applications of biotechnology, future prospects.
104p
muasambanhan10
03-04-2024
3
2
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Genomic medicine has considerable potential to provide novel diagnostic and therapeutic solutions for patients who have molecularly complex diseases and who are not responding to existing therapies. To bridge the gap between genomic medicine and clinical practice, integration of various data types, resources, and joint international initiatives will be required.
3p
vibransone
28-03-2024
3
2
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Whole-exome sequencing (WES) has become an efficient diagnostic test for patients with likely monogenic conditions such as rare idiopathic diseases or sudden unexplained death. Yet, many cases remain undiagnosed. Here, we report the added diagnostic yield achieved for 101 WES cases re-analyzed 1 to 7 years after initial analysis.
8p
vibransone
28-03-2024
3
2
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The increasing affordability of DNA sequencing has allowed it to be widely deployed in pathology laboratories. However, this has exposed many issues with the analysis and reporting of variants for clinical diagnostic use.
16p
vioraclene
31-03-2024
3
2
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Precision medicine approaches are ideally suited for rare tumors where comprehensive characterization may have diagnostic, prognostic, and therapeutic value. We describe the clinical case and molecular characterization of an adolescent with metastatic poorly differentiated carcinoma (PDC).
17p
vioraclene
31-03-2024
8
1
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Cell-free DNA (cfDNA) profiling is increasingly used to guide cancer care, yet mutations are not always identified. The ability to detect somatic mutations in plasma depends on both assay sensitivity and the fraction of circulating DNA in plasma that is tumor-derived (i.e., cfDNA tumor fraction).
15p
vibransone
28-03-2024
3
2
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In medical genetics, discovery and characterization of disease trait contributory genes and alleles depends on genetic reasoning, study design, and patient ascertainment; we suggest a segmental haploid genetics approach to enhance gene discovery and molecular diagnostics.
24p
viellison
28-03-2024
3
2
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Ebook "Designing receptors for the next generation of biosensors" shows how synthetic receptors can be designed with characteristics that make them attractive alternatives to biological molecules in the sensory and diagnostics fields, with contributions from leading experts in the area.
271p
coduathanh1122
27-03-2024
3
1
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Ebook "Functionalized conjugated polyelectrolytes: Design and biomedical applications" presents a comprehensive review of these polyelectrolytes and their biomedical applications. Basic aspects like molecular design and optoelectronic properties are covered in the first chapter. Emphasis is placed on the various applications including sensing (chemical and biological), disease diagnosis, cell imaging, drug/gene delivery and disease treatment.
91p
coduathanh1122
27-03-2024
2
1
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Ebook "Retinal degenerative diseases: Laboratory and therapeutic investigations (Advances in experimental medicine and biology, Volume 664)" provides readers with contents including: basic science underlying retinal degeneration; molecular genetics and candidate genes; diagnostic, clinical, cytopathological and physiologic aspects of retinal degeneration; macular degeneration;...
715p
duongthandue0501
28-02-2024
5
1
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