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Molecular sequences
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The primary aim of this study is to critically evaluate and comment on the research presented in the article titled “A Novel Super-Enhancer-Related Gene Signature Predicts Prognosis and Immune Microenvironment for Breast Cancer” by Wu et al.
3p
vishanshan
27-06-2024
1
1
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Obstructive sleep apnea (OSA) is associated with increased risk of lung cancer mortality. Nevertheless, little is known about the underlying molecular mechanisms. This research aimed to investigate differentially expressed genes (DEGs) and explore their function in Lewis lung carcinoma (LLC)-bearing mice exposed to chronic intermittent hypoxia (CIH) by transcriptome sequencing.
10p
vishanshan
27-06-2024
1
1
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Updating researchers on phenomenal progress in the field of molecular medicine the Encyclopedia of Medical Genomics and Proteomics offers trail-blazing studies and authoritative contributions from more than 400 specialists. Topics include: Molecular diagnostics; Genomics, microbiology, genetics, and pharmacogenetics; Management of infectious, neoplastic, and genetic diseases;...
1391p
vimeyers
29-05-2024
3
2
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In conclusion, sequence analysis may be useful for the rapid detection of STR resistance in MDR M. tuberculosis strains, which in turn could contribute to better control strategies of TB in Vietnam. Other molecular mechanisms associated with STR resistance in STR-resistant strains without mutations in the rpsL and rrs genes need to be further investigated.
11p
dianmotminh02
03-05-2024
4
1
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In this study, numerous Grateloupia spp. collected from coastal Vietnam and voucher specimens were used for morphological observation and phylogenetic analyses. Both analyses for samples collected at Nha Trang reveal a new record of G. yangjiangensis. The phylogenetic trees indicated that the herbarium vouchers labeled ‘G filicina’ and ‘G. livida’ from other locations of Vietnam group to G. yinggehaiensis clade. In addition, the phylogenetic trees also showed that the unknown Grateloupia sp. recently collected from Cat Ba Island is Phyllymenia taiwanensis. Therefore, a new record, G.
12p
dianmotminh02
03-05-2024
6
1
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With the aim of inferring phylogenetic relationships among 86 species (including 45 species from Vietnam) mostly of the subfamily Convallarioideae (=Nolinoideae) (Asparagaceae sensu APG IV), we analyzed their chloroplast DNA sequences (rbcL and trnL-F) by both Bayesian inference (BI) and maximum likelihood (ML) methods. Our dataset included six of the seven tribes classified in this subfamily; Convallarieae, Dracaeneae, Liriopeae Nolineae, Polygonateae and Rusceae (Eriospermeae not examined).
17p
dianmotminh02
03-05-2024
3
2
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Ebook "Mitochondria and cancer" presents thorough analyses of mitochondrial dysfunction as one of the hallmarks of cancer, discusses the clinical implications of mitochondrial defects in cancer, and as unique cellular targets for novel and selective anti-cancer therapy. These include differences in mitochondrial metabolic activity, molecular composition of mitochondria and mtDNA sequence, as well as in alteration of nuclear genes encoding mitochondrial proteins.
294p
ladongphongthanh1008
22-04-2024
4
1
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Ebook "Introduction to computational biology: An evolutionary approach" Analysis of molecular sequence data is the main subject of this introduction to computational biology. There are two closely connected aspects to biological sequences: (i) their relative position in the space of all other sequences, and (ii) their movement through this sequence space in evolutionary time. Accordingly, the first part of the book deals with classical methods of sequence analysis: pairwise alignment, exact string matching, multiple alignment, and hidden Markov models.
329p
tracanhphuonghoa1007
22-04-2024
10
2
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Ebook "Introduction to computational molecular biology" brings together major results in the field, in coherent and readable format. Setubal and Meidanis present a representative sample of problems in molecular biology, focusing on the algorithms that have been proposed to solve them. Readers will find background material on molecular biology, definitions of key terms, descriptions of models, and a full sample of algorithmic results.
308p
tracanhphuonghoa1007
22-04-2024
2
2
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Ebook "Models and algorithms for genome evolution" presents a review of the history, current status, and potential future directions of computational biology in molecular evolution. Gathering together the unique insights of an international selection of prestigious researchers, this must-read volume examines the latest developments in the field, the challenges that remain, and the new avenues emerging from the growing influx of sequence data.
329p
tracanhphuonghoa1007
22-04-2024
2
2
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Part 1 book "Molecular diagnostics - Fundamentals, methods, and clinical applications" includes content: Nucleic acids and proteins; gene expression and epigenetics; nucleic acid extraction methods; resolution and detection of nucleic acids; analysis and characterization of nucleic acids and proteins; nucleic acid amplifi cation; chromosomal structure and chromosomal mutations, gene mutations; DNA sequencing.
280p
muasambanhan10
06-04-2024
2
0
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In Vietnam, SMEDI syndrome in sows caused by PPV is nationwide and has been of concern since the early 1990s. Previous studies have investigated the prevalence of PPVs using serological testing and PCR methods. The objective of this study is to analyze the genotypic prevalence of PPVs and molecular characterization of VP gene of PPV2 from slaughtered pigs in Central Vietnam.
10p
viritesh
02-04-2024
1
1
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Targeted therapies specifically act by blocking the activity of proteins that are encoded by genes critical for tumorigenesis. However, most cancers acquire resistance and long-term disease remission is rarely observed. Understanding the time course of molecular changes responsible for the development of acquired resistance could enable optimization of patients’ treatment options.
22p
vibransone
28-03-2024
3
2
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Large-sequencing cancer genome projects have shown that tumors have thousands of molecular alterations and their frequency is highly heterogeneous. In such scenarios, physicians and oncologists routinely face lists of cancer genomic alterations where only a minority of them are relevant biomarkers to drive clinical decisionmaking.
11p
vibransone
28-03-2024
4
2
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Non-small cell lung cancer (NSCLC) is the most common cause of cancer-related deaths worldwide and is primarily treated with radiation, surgery, and platinum-based drugs like cisplatin and carboplatin. The major challenge in the treatment of NSCLC patients is intrinsic or acquired resistance to chemotherapy. Molecular markers predicting the outcome of the patients are urgently needed.
16p
vibransone
28-03-2024
4
2
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Severe infections with highly virulent community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) are a global problem. However, the molecular events defining the evolution of CA-MRSA are still poorly understood.
14p
vibransone
28-03-2024
3
2
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A comprehensive understanding of cancer has been furthered with technological improvements and decreasing costs of next-generation sequencing (NGS). However, the complexity of interpreting genomic data is hindering the implementation of high-throughput technologies in the clinical context: increasing evidence on gene–drug interactions complicates the task of assigning clinical significance to genomic variants.
15p
vibransone
28-03-2024
3
2
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Despite the increasing recognition that microbial communities within the human body are linked to health, we have an incomplete understanding of the environmental and molecular interactions that shape the composition of these communities.
13p
vibransone
28-03-2024
7
1
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Mutation acquisition is a major mechanism of bacterial antibiotic resistance that remains insufficiently characterised. Here we present RM-seq, a new amplicon-based deep sequencing workflow based on a molecular barcoding technique adapted from Low Error Amplicon sequencing (LEA-seq).
15p
vibransone
28-03-2024
7
2
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Comprehensive mutational profiling data now available on all major cancers have led to proposals of novel molecular tumor classifications that modify or replace the established organ- and tissue-based tumor typing. The rationale behind such molecular reclassifications is that genetic alterations underlying cancer pathology predict response to therapy and may therefore offer a more precise view on cancer than histology.
17p
vibransone
28-03-2024
4
2
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