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Monitoring disease progression

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  • Rheumatoid arthritis is a chronic systemic inflammatory arthritis of auto-immune origin that affects primarily the synovial joints, usually in a symmetrical pattern. It is the most common and most serious of the inflammatory arthritides, and it dominates clinical rheumatological practice (Silman 2002). Current evidence shows that prompt diagnosis and early instigation of definitive disease-modifying treatment can delay or avoid progression and enable patients to retain function that would otherwise be lost in this progressive and frequently disabling disease....

    pdf0p thienbinh1311 13-12-2012 36 4   Download

  • Now is the time to align CHWs with broader health system strengthening efforts at the primary care level, improve CHW financing, and broadly disseminate recent advances in technology, diagnostics and treatment to support community-based health workers. The MDGs have provided the impetus for a new generation of investments accompanied by international progress monitoring of progress through the Countdown to 2015 initiative and the UN Commission on Information and Accountability for Women’s and Children’s Health.

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  • This publication is the fifith in a UNICEF series that monitors progress for children towards achievement of the Millennium Development Goals (MDGs). It assesses current performance in relation to MDG no.7 which aims to halve by 2015 the number of people without sustainable access to safe drinking water and basic sanitation. As well as being vital in themselves, safe water and sanitation are also key prerequisites for achieving other MDGs such as reducing child and materal mortality, combating diseases, reducing child undernutrition and achieving universal primary education.

    pdf92p conchokon 08-01-2013 36 1   Download

  • Circulating tumor cells (CTCs) are metastatic cells disseminated into the bloodstreams. They have been proposed to monitor disease progression for decades. However, the prognostic value of CTCs in gastric cancer (GC) remains controversial. We performed a meta-analysis to investigate the topic.

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  • The U.S. is committed to aligning GHI investments with partner country plans and strategies, primarily through tech- nical assistance, project-level support, and capacity-building of governments and other local institutions. GHI’s capac- ity-building investments include support for policy development, implementation, management, research, monitoring, and evaluation. In countries where the private sector is a vital partner in providing health care, the U.S.

    pdf4p le_minh_nha 20-12-2012 33 5   Download

  • Electronic Medical Records now act as main repositories for patient data. As we con- tinue to explore the intricate relationship between phenotype and genotype, these records become a vital source for monitoring patients’ progression of disease. The pre- sence of a given variation, as it relates to the appearance or absence of disease over time, can be mapped as encounters are recorded by clinicians. Every result, encounter, event, or diagnosis is recorded as a data item and includes a date.

    pdf18p thangbienthai 17-11-2012 57 2   Download

  • Once COPD has been diagnosed, goals of treatment and management include relieving symptoms; preventing and treating disease progression, complications, and exacerbations; improving exercise tolerance, daily activity, and health status; monitoring nutritional needs; and reducing premature mortality (8).

    pdf6p chiecxedien 03-01-2013 42 2   Download

  • EDRN is at the forefront of technology-driven research on the use of biomarkers for the early detection of cancer. By identifying and validat- ing biomarkers, such as novel proteins or changes in gene expression, it is possible to measure an individual’s disease risk, progression of disease, or response to therapy. Ultimately, EDRN research will aid in prevention and in early therapeutic intervention, based on early detection of disease.

    pdf0p khongmuonnghe 07-01-2013 56 2   Download

  • Monitoring and evaluation. Finally, in order to track progress and enhance learning and quality, an effective system of monitoring and evaluation that includes assessment of on-the-ground results is under development. Progress in implementing the strategy will be reported annually. The estimated incremental costs of implementing the strategy will be about $2 million in the current fiscal year, about $3 million per year in the three subsequent years, and approximately $2.5 mil- lion per year thereafter. Corporate incentive funding of $0.

    pdf71p machuavo 19-01-2013 29 2   Download

  • Fall is rodent time. This means it’s also time to step up your rodent monitoring and control efforts. Food resources in the fields and woods are beginning to get scarce for rats and mice this time of the year, forcing them to move into poultry houses where food and water are plentiful. Be ready by tightening up your poultry houses and having plenty of rodenticide on hand. Start with a walk around the poultry houses. Be alert for signs of new rodent activity (gnawing, bits of fallen insulation, droppings, tail marks and tracks). Note the...

    pdf18p loginnhanh 22-04-2013 23 1   Download

  • : Inflammatory mediators can serve as biomarkers for the monitoring of the disease progression or prognosis in many conditions. In the present study we introduce an adaptation of a membrane-based technique in which the level of up to 40 cytokines and chemokines can be determined in both human and rodent blood in a semi-quantitative way.

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  • 18F-FDG PET-CT is commonly used to monitor treatment response in patients with metastatic colorectal cancer (mCRC). With improvement in systemic therapy, complete metabolic response (CMR) is increasingly encountered but its clinical significance is undefined.

    pdf10p vimanila2711 29-06-2020 0 0   Download

  • Identifying and tracking somatic mutations in cell-free DNA (cfDNA) by next-generation sequencing (NGS) has the potential to transform the clinical management of subjects with advanced non-small cell lung cancer (NSCLC).

    pdf9p viamsterdam 18-09-2020 1 0   Download

  • The global cost of communicable diseases is expected to rise. SARS has put the world on alert. We have now Avian Flu on the watch. Recognizing the global nature of threats posed by new and re-emerging infectious diseases and the fact that many recent occurrences originated in the Asia Pacific regions, there has been an increased interest in learning and knowing about disease surveillance and monitoring progresses made in these regions. Such knowledge and awareness is necessary to reduce conflict, discomfort, tension and uneasiness in future negotiations and global cooperation....

    pdf317p japet75 30-01-2013 32 8   Download

  • Genetics of autoimmune diseases represent a growing domain with surpassing biomarker results with rapid progress. The exact cause of Rheumatoid Arthritis (RA) is unknown, but it is thought to have both a genetic and an environmental bases. Genetic biomarkers are capable of changing the supervision of RA by allowing not only the detection of susceptible individuals, but also early diagnosis, evaluation of disease severity, selection of therapy, and monitoring of response to therapy. This review is concerned with not only the genetic biomarkers of RA but also the methods of identifying them.

    pdf16p kequaidan1 16-11-2019 5 0   Download

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