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Monozygotic twin
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Rheumatoid arthritis is a common autoimmune disorder influenced by both genetic and environmental factors. Epigenome-wide association studies can identify environmentally mediated epigenetic changes such as altered DNA methylation.
12p
vibransone
28-03-2024
3
2
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In addition, lip prints are form of wrinkles and grooves including normal lines, fissures and are present in the zone of transition of human lip between the inner labial mucosa and outer skin. Lip prints are also a main evidence for identification of an individual in a forensic dentistry due to its uniqueness, except in monozygotic twins.
12p
viberbers
09-08-2023
4
3
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Monozygotic twins (MZT) are an important resource for genetical studies in the context of normal and diseased genomes. In the present study we used DYZ1, a satellite fraction present in the form of tandem arrays on the long arm of the human Y chromosome, as a tool to uncover sequence variations between the monozygotic males.
12p
vinarcissa
21-03-2023
2
1
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Monozygotic twins have long been studied to estimate heritability and explore epigenetic influences on phenotypic variation. The phenotypic and epigenetic similarities of monozygotic twins have been assumed to be largely due to their genetic identity.
20p
vialfrednobel
29-01-2022
6
0
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CpG methylation variation is involved in human trait formation and disease susceptibility. Analyses within populations have been biased towards CpG-dense regions through the application of targeted arrays. We generate whole-genome bisulfite sequencing data for approximately 30 adipose and blood samples from monozygotic and dizygotic twins for the characterization of non-genetic and genetic effects at single-site resolution.
18p
viaristotle
29-01-2022
17
0
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Illumina DNA methylation microarrays enable epigenome-wide analysis vastly used for the discovery of novel DNA methylation variation in health and disease. However, the microarrays’ probe design cannot fully consider the vast human genetic diversity, leading to genetic artifacts.
29p
viarchimedes
26-01-2022
10
0
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Although the genomes of monozygotic twins are practically identical, their methylomes may evolve divergently throughout their lifetime as a consequence of factors such as the environment or aging. Particularly for young and healthy monozygotic twins, DNA methylation divergence, if any, may be restricted to stochastic processes occurring post-twinning during embryonic development and early life.
23p
viarchimedes
26-01-2022
9
0
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The therapeutic management of obesity is challenging, hence further elucidating the underlying mechanisms of obesity development and identifying new diagnostic biomarkers and therapeutic targets are urgent and necessary. Here, we performed differential gene expression analysis and weighted gene co-expression network analysis (WGCNA) to identify significant genes and specific modules related to BMI based on gene expression profile data of 7 discordant monozygotic twins.
17p
vilarryellison
29-10-2021
15
0
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Congenital heart disease (CHD) is the leading non-infectious cause of death in infants. Monozygotic (MZ) twins share nearly all of their genetic variants before and after birth. Nevertheless, MZ twins are sometimes discordant for common complex diseases. The goal of this study is to identify genomic and epigenomic differences between a pair of twins discordant for a form of congenital heart disease, double outlet right ventricle (DORV).
13p
vibeauty
23-10-2021
10
0
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Studies of twin pairs discordant for autoimmune conditions provide a unique opportunity to explore contributing factors triggered by complex gene-environment interactions. Methods: In this cross-sectional study, thirty-one monozygotic or dizygotic twin pairs discordant for myositis or systemic lupus erythematosus (SLE), along with matched healthy controls were evaluated for antibodies against a panel of 21 autoantigens.
11p
viannito2711
20-04-2021
12
2
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CFTR modulator therapy with ivacaftor is a treatment option for Cystic Fibrosis (CF) patients with at least one copy of a R117H-7T mutation in the CFTR gene. Desirable effects of this therapy are improvement of lung function, decrease in exacerbation rate, normalization or reduction of sweat chloride and weight gain.
6p
vimaine2711
26-03-2021
16
2
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Studies involving the analysis of structural variation including Copy Number Variation (CNV) have recently exploded in the literature. Furthermore, CNVs have been associated with a number of complex diseases and neurodevelopmental disorders.
8p
vikentucky2711
26-11-2020
7
1
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Personality traits, which can be described as differences between individuals regarding their behavior, thoughts, and feelings, can be seen as relatively stable in different situations and over time (Specht et al., 2014). A pair of 90 twins in the age group of 3-6 years from five cultural zones of state Haryana was taken. A Five Factor Personality Questionnaire (Cathy, 2011) was used for assessing the personality traits of preschool twins.
5p
kethamoi5
03-06-2020
4
0
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Identical (monozygotic) twins have essentially the same set of genes. Identical twins are more similar than fraternal twins on a range of personality measures, indicating that characteristics are heritable. Personality and specific genes responsible for the ubiquitous heritability of personality traits has increasingly become a target for genetic research. The study was conducted in five cultural zones of Haryana state namely Khadar, Bagar, Nardak, Mewat and Ahirwal.
4p
trinhthamhodang1213
30-05-2020
19
0
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Fetus in fetu is a rare congenital anomaly and is defined as a monozygotic twin incorporated into the abdomen of its sibling during development. Fetus in fetu is often overlooked in the differential diagnosis of an abdominal mass. Unlike teratomas, fetus in fetu is a benign disorder.
6p
vinatri2711
29-02-2020
15
1
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Plastic bronchitis is an extremely rare disease characterized by the formation of tracheobronchial airway casts, which are composed of a fibrinous exudate with rubber-like consistency and cause respiratory distress as a result of severe airflow obstruction.
5p
vinatri2711
29-02-2020
15
1
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(BQ) Tài liệu Like science: Continuing the Species includes of what is the difference between a gene and an allele? How does a mutation cause a new trait? How are monozygotic and dizygotic twins different? Sequence What is the sequence of steps taken by people who wish to breed a new type of organism with certain traits?.
14p
thieulam5782
04-10-2015
40
3
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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Gene expression profiles from discordant monozygotic twins suggest that molecular pathways are shared among multiple systemic autoimmune diseases...
13p
thulanh15
21-10-2011
43
2
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Tuyển tập các báo cáo nghiên cứu khoa học ngành y học tạp chí Medical Sciences dành cho các bạn sinh viên ngành y tham khảo đề tài: Mirror-Image Arachnoid Cysts in a Pair of Monozygotic Twins: A Case Report and Review of the Literature...
4p
thulanh9
07-10-2011
43
5
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Multiple pregnancy involves more than one embryo (fetus) in any one gestation. Two independent mechanisms may lead to multiple gestation: segmentation of a single fertile ovum (identical, monovular, or monozygotic) or fertilization of separate ova by different spermatozoa (fraternal or dizygotic) multiple pregnancy. In the development of twins (the most frequent higher-order gestation), monozygotism is constant ( 2.3–4/1000 deliveries), whereas dizygotism has certain predispositions. Dizygotic twinning is inherited as a recessive autosomal trait via the female descendants.
12p
lananhanh123
27-08-2011
88
9
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