Motif enrichment

The development of sequencing technologies has promoted the survey of genomewide chromatin accessibility at single-cell resolution. However, comprehensive analysis of single-cell epigenomic profiles remains a challenge.

27p viarchimedes 26-01-2022 10 0   Download

The acetic acid bacterium Gluconobacter oxydans 621H is characterized by its exceptional ability to incompletely oxidize a great variety of carbohydrates in the periplasm. The metabolism of this α-proteobacterium has been characterized to some extent, yet little is known about its transcriptomes and related data. In this study, we applied two different RNAseq approaches. Primary transcriptomes enriched for 5′-ends of transcripts were sequenced to detect transcription start sites, which allow subsequent analysis of promoter motifs, ribosome binding sites, and 5´-UTRs.

17p vilarryellison 29-10-2021 12 1   Download

Promoter motifs in Entamoeba histolytica were earlier analysed using microarray data with lower dynamic range of gene expression. Additionally, previous transcriptomic studies did not provide information on the nature of highly transcribed genes, and downstream promoter motifs important for gene expression.

18p visilicon2711 20-08-2021 8 1   Download

Short linear protein motifs are attracting increasing attention as functionally independent sites, typically 3–10 amino acids in length that are enriched in disordered regions of proteins. Multiple methods have recently been proposed to discover over-represented motifs within a set of proteins based on simple regular expressions.

9p viwyoming2711 16-12-2020 9 0   Download

The heterogeneity of cells across tissue types represents a major challenge for studying biological mechanisms as well as for therapeutic targeting of distinct tissues. Computational prediction of tissue-specific gene regulatory networks may provide important insights into the mechanisms underlying the cellular heterogeneity of cells in distinct organs and tissues.

15p viconnecticut2711 28-10-2020 13 1   Download

Sequence logo plots have become a standard graphical tool for visualizing sequence motifs in DNA, RNA or protein sequences. However standard logo plots primarily highlight enrichment of symbols, and may fail to highlight interesting depletions. Current alternatives that try to highlight depletion often produce visually cluttered logos.

9p vicoachella2711 27-10-2020 7 1   Download

The dynamism of fashion industry has forced retailers to desire low cost, versatility, flexibility and quality in design and speed to market. Highly competitive fashion market constantly needs to „refresh‟ product ranges which led to the appearance of small collections of merchandise. The rich traditional heritage, across the length and width of our country, offers diverse inspiration to the textile designers today.

10p cothumenhmong3 22-02-2020 13 0   Download