![](images/graphics/blank.gif)
Mouse neuronal cells
-
Part 2 book "Mouse cell culture - Methods and protocols" includes content: Short and long term cultivation of embryonic and neonatal murine keratinocytes; isolation, culture and analysis of mouse mammary epithelial cells; isolation and culture of adult mouse hepatocytes; isolation and culture of mouse intestinal cells; the preparation of primary cortical neuron cultures and a practical application using immunofluorescent cytochemistry; ... and other contents.
143p
muasambanhan04
07-01-2024
1
1
Download
-
Results of the histological assessment of the prefrontal cortex reveal normal histology for T0, marked with an intact nucleus, and prominent and organized cells. Tissue architecture for T- reveals the reduction of cells and necrosis. T+ and T1 groups both maintained intact and well-stained nuclei that are comparable with T0. Interestingly, cellular proliferation has been noted for the Z. talanai group, which indicates possible neuronal differentiation. Overall, Z. talanai extract has been observed to exert antinecrotic capacities in the mouse brain.
7p
nhanchienthien
25-07-2023
3
2
Download
-
Fragile X syndrome (FXS) is an intellectual disability attributable to loss of fragile X protein (FMRP). We previously demonstrated that FMRP binds mRNAs targeted for nonsense-mediated mRNA decay (NMD) and that FMRP loss results in hyperactivated NMD and inhibition of neuronal differentiation in human stem cells.
13p
viarchimedes
26-01-2022
21
1
Download
-
In this study, three alkaloid fractions from Huperzia serrata (Thunb.) Trevis, Lycopodium clavatum L. and Huperzia squarrosa (G. Forst.) Trevis were tested in two toxicity models: mouse primary neuronal cell (in vitro) and zebrafish (Danio rerio) embryos (in vivo).
9p
guitaracoustic02
08-12-2021
15
1
Download
-
A series of new thiazole-hydrazones (3a–3n) were synthesized, characterized, and screened for their hMAOA and hMAO-B inhibitory activity by an in vitro fluorometric method. Selectivity indexes (SIs) were expressed as IC50 (MAO-A) / IC50 (MAO-B). Compound 3f showed promising hMAO-A inhibition with an IC50 value of 1.20 µM and displayed a very significant SI of 0.04 towards hMAO-A. The mechanism of hMAO-A inhibition was investigated by enzyme kinetics using Lineweaver–Burk graphics.
15p
tudichquannguyet
29-11-2021
8
0
Download
-
Emerging evidence indicates that long noncoding RNAs (lncRNAs) are important regulators of various biological processes, and their expression can be altered following certain pathological conditions, including central nervous system injury. Retinal ganglion cells (RGCs), whose axons form the optic nerve, are a heterogeneous population of neurons with more than 40 molecularly distinct subtypes in mouse.
16p
vilarryellison
29-10-2021
7
1
Download
-
Mecp2 null mice model Rett syndrome (RTT) a human neurological disorder affecting females after apparent normal pre- and peri-natal developmental periods. Neuroanatomical studies in cerebral cortex of RTT mouse models revealed delayed maturation of neuronal morphology and autonomous as well as non-cell autonomous reduction in dendritic complexity of postnatal cortical neurons.
13p
vioklahoma2711
19-11-2020
8
2
Download
-
Exposure to chemicals might be toxic to the developing brain. There is a need for simple and robust in vitro cellular models for evaluation of chemical-induced neurotoxicity as a complement to traditional studies on animals.
11p
vimax2711
30-03-2020
9
1
Download
-
The non-reducing disaccharide trehalose is biosynthesized in several species but not in vertebrates. However, trehalase, the enzyme required for its cleavage, has been observed in different mammalian organs. Even in humans, trehalase was detected in the gastrointestinal tract and the kidney. Trehalase is an intrinsic glycoprotein of the small intestine and kidney that transports trehalose and hydrolyses it to two glucose molecules. To our knowledge, no information is available about the in vivo distribution and localization of trehalase in the mammalian brain.
9p
caygaocaolon1
13-11-2019
14
0
Download
-
Hsp105aisoneof themajormammalianheat shockproteins that belongs to the HSP105/110 family, and is expressed at especially high levels in the brain as compared with other tissues in mammals. Previously, we showed that Hsp105a prevents stress-induced apoptosis in neuronal PC12 cells, and is a novel anti-apoptotic neuroprotective factor in the mammalian brain.
9p
research12
23-04-2013
37
1
Download
-
The vanilloid-like TRP-channel VRL-1 (TRPV2) is a non-selective cation channel expressed by primary sensory neurons and non-neuronal tissues [Caterina, M.J., Rosen, T.A., Tominaga, M., Brake, A.J and Julius, D. (1999) Nature398, 436–441]. It is one of the six members of the vanilloid-like TRP-channel family which is now termed the TRPV family [Montell, G., Birnbaumer, L., Flockerzi, V., Bindels, R.J., Brutford, E.A., Caterina, M.J., Clapham, D.E., Harteneck, C., Heller, S., Julius, D., Kojima, I., Mori, Y., Penner, R., Prawitt, D., Scharenberg, A.M., Schultz, G., Shimizu, N. and Zhu, M.X.
8p
tumor12
20-04-2013
27
2
Download
-
The PAT2 transporter has been shown to act as an electro-genic proton/amino acid symporter. The PAT2 cDNA has been cloned fromvarious human, mouse and rat tissues and belongs to a group of four genes (pat1topat4)withPAT3 and PAT4 still resembling orphan transporters. The first immunolocalization studies demonstrated that the PAT2 protein is found in the murine central nervous system in neuronal cells with a proposed role in the intra and/or intercellular amino acid transport.
8p
awards
05-04-2013
51
4
Download
-
The single-copy mouse genePtprrgives rise to different protein tyrosine phosphatase (PTP) isoforms in neuronal cells through the use of distinct promoters, alternative splicing, and multiple translation initiation sites. Here, we examined the array of post-translational modifications imposed on the PTPRR protein isoforms PTPBR7, PTP-SL, PTPPBSc42 and PTPPBSc37, which have distinct N-terminal segments and localize to dif-ferent parts of the cell.
13p
inspiron33
23-03-2013
36
3
Download
-
Signal transducers and activators of transcription (STATs) regulate a vari-ety of cellular functions, including differentiation and proliferation. STAT3 and STAT5 are known to play important roles in brain processes, such as energy homeostasis and neuronal development. We isolated a novel splicing variant ofSTAT5Afrom a cDNA library of the mouse brainstem.
12p
viettel02
20-02-2013
30
2
Download
-
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: Modified cell cycle status in a mouse model of altered neuronal vulnerability (slow Wallerian degeneration; Wlds)...
0p
thulanh20
12-11-2011
36
2
Download
CHỦ ĐỀ BẠN MUỐN TÌM
![](images/graphics/blank.gif)