Mucosal nodules

Mucosal nodules can be caused by infection, inflammation and neoplastic disease. Many noninfectious diseases, such as eosinophilia, amyloidosis, sarcoidosis, Wegener’s granuloma, langerhans cell histiocytosis etc., are associated with the formation of multisytem mucosal nodules, especially significant bronchial lesions.

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Unfortunately not much more was published about prostate aspiration biopsies for the next 20 years. Then in 1960 Parry and Finelli described a modified method which was highly successful in allowing a directed biopsy through the perineum (Parry and Finelli, 1960). Their technique afforded greater needle control by using digital-guidance.

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