Multidrug resistant organisms
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Bacterial whole-genome sequencing (WGS) has the potential to identify reservoirs of multidrugresistant organisms and transmission of these pathogens across healthcare networks. We used WGS to define transmission of vancomycin-resistant enterococci (VRE) within a long-term care facility (LTCF), and between this and an acute hospital in the United Kingdom (UK).
9p vioraclene 31-03-2024 2 2 Download
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Nursing home residents have increased rates of intestinal colonisation with multidrug-resistant organisms (MDROs). We assessed the colonisation and spread of MDROs among this population, determined clinical risk factors for MDRO colonisation and investigated the role of the gut microbiota in providing colonisation resistance against MDROs.
17p vibransone 28-03-2024 3 1 Download
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The aim of this study was to perform an audit in order to assess whether, at the time of writing, the relevant policies and procedures were in place at the King Fahad Hofuf Hospital. The Carter and colleagues’ model, which uses a matrix of acknowledging, auditing, stating of aims, and setting out of actions was used as a model for the assessment of the policies.
20p vikissinger 21-12-2023 1 1 Download
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Multidrug resistance-associated protein 1 (MRP1), encoded by the ABCC1 gene, is an ATP-binding cassette transporter mediating efflux of organic anions and xenobiotics; its overexpression leads to multidrug resistance.
16p vinarcissa 21-03-2023 4 1 Download
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The sensitivity of some pathogenic bacteria used as test organisms to the new compounds 1–3 was determined. 1 showed appreciable antimicrobial activity with the diameter of inhibition zones ranging from 11 to 18 mm. 1 was active against the two multidrug resistant bacteria Acinetobacter baumannii and Staphylococcus aureus. Minimal inhibitory concentrations (MICs) of compound 1 were recorded for all the tested bacteria using the fluorescein diacetate method and the recorded MIC values ranged from 4 to 6 µM.
8p langthannam 29-12-2021 8 0 Download
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As an important group of the multidrug efflux transporter family, the multidrug and toxic compound extrusion (MATE) family has a wide range of functions and is distributed in all kingdoms of living organisms. However, only two MATE genes in apple have been analyzed and genome-wide comprehensive analysis of MATE family is needed.
14p vitzuyu2711 29-09-2021 11 1 Download
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One of several reasons that the concept of healthcare-associated pneumonia (HCAP) was dismissed was the same presence of multidrug resistant organism (MDRO) between community-acquired pneumonia and HCAP at countries with the low prevalence of antimicrobial resistance (AMR). However, this finding could be unsuitable for countries with the high rates of AMR.
5p nguaconbaynhay11 07-04-2021 9 1 Download
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To determine the distribution and genetic diversity of A. baumannii strains isolated from inpatients at Thanh Nhan Hospital from 10/2017 to 10/2018. Subjects and methods: A descriptive study and laboratory analysis on sixty-seven A. baumannii strains from isolated samples of inpatient at Thanh Nhan Hospital from 2017 to 2018.
8p vimanoban2711 13-04-2021 6 1 Download
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F-fluorodeoxyglucose positron emission tomography (FDG-PET) is increasingly used to investigate for malignancy in the evaluation of pulmonary nodules, yet both active tuberculosis (TB) and malignancy have high uptake of FDG. Definitive diagnosis of TB can be further hindered in patients without growth of the organism from sputum.
5p vimontana2711 05-04-2021 17 2 Download
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This study was organized to determine the in vitro activity of tigecycline and colistin against MDR K. pneumoniae isolates retrieved from one Egyptian tertiary care hospital.
9p nguaconbaynhay10 22-01-2021 9 1 Download
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A study of bacterial uropathogens and their antibiotic sensitivity pattern in a tertiary care centre
Urinary tract infection (UTI) is one of the most common infection seen in clinical practice in all age groups. The UTI is most commonly caused by E.coli. There is emergence of multidrug resistant bacteria because of inadvertent use of antibiotics in treating these infections. The changing trend of pathogens and their antibiotic sensitivity the study has been undertaken, to determine the bacteria causing the UTI and find their antibiotic sensitivity. A total of 200 urine specimens showing the significant bacteriuria are studied. The midstream urine samples collected in a sterile container.
5p trinhthamhodang9 16-12-2020 9 1 Download
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Members of the genus Myroides namely, M. odoratus and M. odoratimimus are ubiquitous in nature. Over past decade, these Gram negative bacteria are increasingly being implicated in various life threatening infections in health care setting. Here we report a case of urosepsis due to multi-drug resistant M. odoratimimus in a 41 year old male with anaplastic astrocytoma. The case highlights the importance of surveillance of multidrug resistant organisms in intensive care units of hospital.
6p nguathienthan8 20-10-2020 7 1 Download
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This study aimed to characterize Klebsiella isolated from all clinical samples, determine their antibiogram by disc diffusion method and confirm the presence of ESBL, Carbapenemase in multidrug resistant strains by phenotypic methods and the results will help in instituting infection control against these organisms.
11p quenchua8 29-09-2020 7 0 Download
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India accounts for 30% of neonatal deaths globally. Bacterial sepsis is a significant cause of morbidity and mortality in newborns. The study helps to make antibiotic policy in neonatal sepsis. The main objective is to study the incidence of multidrug resistant gram negative and gram positive organisms causing neonatal septicemia and their antibiotic sensitivity pattern. The study was conducted in the Department of Microbiology over a period of one year. Sample of blood was collected under aseptic precautions and processed by standard techniques.
5p gaocaolon5 14-06-2020 20 2 Download
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The severity and extent of disease caused by multidrug-resistant organisms (MDROs) varies by the population(s) affected and the institution(s) at which these organisms are found; therefore, preventing and controlling MDROs are extremely important.
11p angicungduoc5 12-06-2020 6 0 Download
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2-Aminothiazoles are significant class of organic medicinal compounds utilized as starting material for the synthesis of diverse range of heterocyclic analogues with promising therapeutic roles as antibacterial, antifungal, anti-HIV, antioxidant, antitumor, anthelmintic, anti-inflammatory & analgesic agents.
13p vijiraiya2711 27-05-2020 16 1 Download
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Campylobacteriosis is considered an emerging public health problem with a higher morbidity and mortality rate and a significant impediment to socioeconomic development worldwide. Pigs act as a major reservoir host of Campylobacter spp. The organism colonizes the intestinal tract and can persist for the entire lifespan in pigs without any disease manifestation and pose a significant threat to farm biosecurity. The emergence of multidrug resistant strains of Campylobacter spp. in recent years has been attributed to the indiscriminate use of antimicrobial agents in animal production.
7p trinhthamhodang5 16-05-2020 10 1 Download
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Klebsiella species belonging to the family Enterobacteriaceae, are known to cause a variety of human infections such as pneumonia, urinary tract infections, septicaemia, soft tissue infections and are an important cause of healthcare associated infections. The emergence of multidrug resistant Klebsiella is a growing problem worldwide. Klebsiella spp. are one of the most common organisms to carry plasmids encoding ESBL enzyme. They are associated with higher rates of treatment failure and death.
6p chauchaungayxua5 05-05-2020 19 2 Download
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Non-fermenting gram negative bacilli (NFGNB) are known to account for nearly 12- 16% all bacterial isolates from a clinical microbiology laboratory. The most common infections caused by these organisms were septicemia, pneumonia, urinary tract infections, surgical site infections, wound infections, osteomyelitis, etc. As multidrug resistances being very common and increasing among NFGNB and Pseudomonas and Acinetobacter being the most predominantly isolated NFGNB and its resistance towards colistin and imepenam type of antimicrobials is of major concern.
8p kethamoi4 16-04-2020 11 0 Download
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To isolate common organisms from suspected cases of septicemia with their antimicrobial susceptibility pattern and know the prevalence of MDR strains by detecting MRSA isolates, ESBL, AmpC and Carbapenemase production. Blood samples were collected from suspected cases of septicemia and incubated in BacT/ALERT 3D. Subculture was done on Blood agar, nutrient Agar, MacConkey Agar and Chocolate Agar and identification was done by standard biochemical reactions.
11p trinhthamhodang1212 06-04-2020 7 0 Download