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Multidrug resistant pathogens
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This volume offers a comprehensive overview of basic and applied aspects of Staphylococcus aureus, which is one of the most important human pathogens. It includes sixteen chapters that address the microbiology and immunology of S. aureus, the pathology of its key manifestations, and the current standard of care. Further, it reviews cutting-edge advances in alternative therapeutic and prophylactic approaches to antibiotics.
543p
vimeyers
29-05-2024
2
2
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Carbapenem-resistant Enterobacteriaceae are considered by WHO as “critical” priority pathogens for which novel antibiotics are urgently needed. The dissemination of carbapenemase-producing Escherichia coli (CP-Ec) in the community is a major public health concern. However, the global molecular epidemiology of CP-Ec isolates remains largely unknown as well as factors contributing to the acquisition of carbapenemase genes.
18p
vibransone
28-03-2024
4
2
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The recent emergence and dissemination of high-level mobile tigecycline resistance Tet(X) challenge the clinical effectiveness of tigecycline, one of the last-resort therapeutic options for complicated infections caused by multidrug-resistant Gram-negative and Gram-positive pathogens.
13p
vibransone
28-03-2024
4
2
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Residents of long-term care facilities (LTCF) may have high carriage rates of multidrug-resistant pathogens, but are not currently included in surveillance programmes for antimicrobial resistance or healthcareassociated infections. Here, we describe the value derived from a longitudinal epidemiological and genomic surveillance study of drug-resistant Escherichia coli in a LTCF in the United Kingdom (UK).
11p
vioraclene
31-03-2024
2
2
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Bacterial whole-genome sequencing (WGS) has the potential to identify reservoirs of multidrugresistant organisms and transmission of these pathogens across healthcare networks. We used WGS to define transmission of vancomycin-resistant enterococci (VRE) within a long-term care facility (LTCF), and between this and an acute hospital in the United Kingdom (UK).
9p
vioraclene
31-03-2024
2
2
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Limited treatment options are available for patients infected with multidrug (MDR)- or pan-drug (PDR)- resistant bacterial pathogens, resulting in infections that can persist for weeks or months. In order to better understand transmission and evolutionary dynamics of MDR Acinetobacter baumannii (Ab) during long-term infection, we analyzed genomes from a series of isolates from individual patients at isolate-specific, patient-specific, and population levels.
12p
vioraclene
31-03-2024
3
2
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Streptococcus pneumoniae is a gram-positive opportunistic pathogen, and infection risks of S. pneumoniae can be profoundly augmented by its acquired multidrug-resistance (MDR). The rapid development of MDR in S. pneumoniae was attributed to the international dissemination of a small number of multidrug-resistant “clones.”
13p
vicwell
29-02-2024
1
1
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Extra-intestinal pathogenic Escherichia coli (ExPEC) are a leading cause of bloodstream and urinary tract infections worldwide. Over the last two decades, increased rates of antibiotic resistance in E. coli have been reported, further complicating treatment.
13p
vicwell
29-02-2024
1
1
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Ebook "Bacterial multidrug exporters: Methods and protocols" to provide protocols involving these vital intrinsic membrane proteins widely distributed in bacteria. Beginning with protocols for the structural analysis of bacterial multidrug exporters, the book continues with sections on biochemical and bioengineering analysis, computational analysis, biomedical approaches, as well as advanced technologies expected to be applied to multidrug efflux transport studies.
351p
lamquandat
28-12-2023
3
2
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To evaluate the value of CTX-M on the clinical outcome of bloodstream infection (BSI) patients caused by E. coli and K. pneumoniae. Subject and method: A total of 165 BSI patients were treated at 108 Military Central Hospital from Oct. 2014 to May 2016, including 115 cases caused by E. coli and 50 cases caused by K. pneumoniae.
6p
vishekhar
01-11-2023
1
0
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Part 1 book How to overcome the antibiotic crisis - Facts, challenges, technologies and future perspectives" includes content: tackling threats and future problems of multidrug resistant bacteria, emergence and spread of antimicrobial resistance - recent insights from bacterial population genomics, diagnostics and resistance profiling of bacterial pathogens, anti virulence strategies to target bacterial infections..... and other contents.
211p
oursky06
17-10-2023
6
3
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Part 1 book "Humans, horses and events management" includes content: Tackling threats and future problems of multidrug resistant bacteria, emergence and spread of antimicrobial resistance - recent insights from bacterial population genomics, epidemiology of staphylococcus aureus nasal carriage patterns in the community, diagnostics and resistance profiling of bacterial pathogens,.... and other contents.
113p
oursky06
17-10-2023
2
2
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Salmonella enterica is one of the most dangerous food-borne pathogens posing a significant global concern especially to travelers returning from developing countries. The present study aimed to evaluate the phenotypic and genotypic antimicrobial resistances of Salmonella from chicken carcasses.
11p
vimulcahy
18-09-2023
7
3
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Mycobacterium abscessus complex is a group of rapidly growing, multidrug-resistant nontuberculous mycobacteria (NTM) species causing serious respiratory and skin and soft tissue infections (SSTIs), yet often underdiagnosed and forgotten.
5p
viberbers
09-08-2023
4
2
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Over the past decades, researchers and scientists have paid more and more attention to the discovery of novel antibiotics and anticancer agents in fighting infection and cancer diseases. It is believed that endophytic actinomycetes from medicinal plants provide abundant resources for new compounds with significant bioactive properties. In the present study, we assessed antibacterial and cytotoxic activities of endophytic actinomycetes associated with Litsea cubeba (Lour.) Pers.
11p
vidudley
20-02-2023
7
2
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In this study, the synthesis of dimeric disulfide-Schiff bases was carried out using two methods. The structures of the obtained Schiff bases were elucidated by various spectroscopic methods as well as elemental analysis. The Schiff base derivative compounds (3a-6) were screened for in vitro antibacterial activity against multidrug-resistant microorganisms using microdilution method. All the tested compounds showed varying inhibition zones against the pathogens.
22p
lyhuyenthu
31-01-2023
9
2
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Antibiotics exposure has been implicated in the emergence of bacterial strains that are resistant to structurally related or unrelated antibiotics. Tylosin is a macrolide antibiotic that has been administered to treat respiratory pathogenic bacteria in swine.
8p
vigalileogalilei
28-02-2022
23
1
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A longitudinal analysis of malaria parasite genomes has revealed new markers that can be used in public health efforts to limit the spread of multidrug-resistant malaria.
3p
vialfrednobel
29-01-2022
10
0
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The sensitivity of some pathogenic bacteria used as test organisms to the new compounds 1–3 was determined. 1 showed appreciable antimicrobial activity with the diameter of inhibition zones ranging from 11 to 18 mm. 1 was active against the two multidrug resistant bacteria Acinetobacter baumannii and Staphylococcus aureus. Minimal inhibitory concentrations (MICs) of compound 1 were recorded for all the tested bacteria using the fluorescein diacetate method and the recorded MIC values ranged from 4 to 6 µM.
8p
langthannam
29-12-2021
8
0
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Furthermore, infections with multi-drug resistant pathogens whether in hospitals or in the community increase morbidity, decrease treatment success, reduce hospital turn-over rate and increase cost of patient care (Alebachew et al., 2012).
9p
caygaocaolon11
21-04-2021
22
1
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