Multifunctional cytokine
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Hepatocyte growth factor (HGF) is a peptide-containing multifunctional cytokine, which is overexpressed and/or activated in multiple malignancies and is reported to be associated with tumor development and inferior survival. At present, the role of HGF in small cell lung cancer (SCLC) has not been fully explored yet.
10p visharma 20-10-2023 4 2 Download
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IL-33 is a multifunctional cytokine with dual functions. However, the clinicopathological and prognostic significance of IL-33 in cancer patients, especially in patients with hepatocellular carcinoma (HCC), remains controversial.
15p vioracle 29-09-2023 7 3 Download
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Interleukin-27 (IL-27) is a multifunctional cytokine with both pro-inflammatory and immunoregulatory functions. At present, the role of IL-27 in pulmonary fibrosis remains unknown. This study demonstrates that IL-27 potentially attenuates BLM-induced pulmonary fibrosis by regulating Th17 differentiation and cytokine secretion.
8p vimontana2711 05-04-2021 10 2 Download
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Interleukin (IL)-11 is a multifunctional cytokine that stimulates hematopoi-etic progenitor cells and exerts a series of important immunomodulatory effects. It was believed to be restricted to mammals, but here we report the first nonmammalianIL-11 gene, in rainbow trout (Oncorhynchus mykiss). A trout IL-11 cDNA clone was isolated that contains a 5¢-untranslated region (UTR) of 400 bp, an open reading frame of 612 bp and a large 3¢-UTR of 1924 bp.
12p awards 05-04-2013 26 2 Download