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Multiple comparisons
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When interpreting sequencing data from multiple spatial or longitudinal biopsies, detecting sample mix-ups is essential, yet more difficult than in studies of germline variation. In most genomic studies of tumors, genetic variation is detected through pairwise comparisons of the tumor and a matched normal tissue from the sample donor.
9p
vibransone
28-03-2024
2
2
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Measuring host gene expression is a promising diagnostic strategy to discriminate bacterial and viral infections. Multiple signatures of varying size, complexity, and target populations have been described. However, there is little information to indicate how the performance of various published signatures compare to one another.
14p
viellison
28-03-2024
5
2
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Part 2 book "Biostatistics - A methodology for the health sciences" includes content: Association and prediction - multiple regression analysis and linear models with multiple predictor variables; multiple comparisons; discrimination and classification; principal component analysis and factor analysis; rates and proportions; analysis of the time to an event - survival analysis; sample sizes for observational studies; longitudinal data analysis; randomized clinical trials; personal postscript.
453p
muasambanhan06
03-02-2024
6
1
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Synchronous multiple primary esophageal squamous cell carcinoma (S-MPESCC) refers to more than one primary esophageal carcinoma detected in a solitary patient at the time of initial presentation. The purpose of this study was to evaluate the clinicopathological features, appropriate surgical approaches and long-term survival in patients with S-MPESCC by comparing with those with solitary esophageal squamous cell carcinoma (SESCC).
13p
vileonardodavinci
23-12-2023
5
2
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Ebook "Evaluation and decision models with multiple criteria: Stepping stones for the analyst" provides a "decision aiding methodology" based on the science of formal decision models that a decision analyst can apply to many decision problems with maximum flexibility. The authors' unique decision aiding process is discussed step-by-step throughout the book. A step-by-step icon is placed in the margin whenever a decision aiding 'stepping stone' is discussed or a conclusion is presented.
460p
loivantrinh
29-10-2023
4
3
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Part 2 book "Foundations of clinical research - Applications to evidence based practice" includes content: Descriptive statistics, foundations of statistical interference; comparing two means - the t-test, comparing more than two means - analysis of variance; multiple comparison tests; nonparametric tests for group comparisons; measuring association for categorical variables - chi square.... and other contents.
356p
oursky07
23-10-2023
1
1
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The optimal treatment for multiple brain metastases has been recently controversially discussed.This study was aimed to explore the feasibility of Hippocampus-Avoidance Whole-Brain Radiotherapy plus a simultaneous integrated boost (HA-WBRT+SIB) in patients with multiple brain metastases and assess tumor control in comparison with Hippocampus-Avoidance Whole-Brain Radiotherapy (HA-WBRT) alone for brain metastases.
11p
vioracle
29-09-2023
6
2
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Part 1 book "Genomic selection in animals" includes content: The multiple comparison problem, linkage mapping of QTL, marker‐assisted selection - basic strategies genetic evaluation based on dense marker maps - basic strategies, genomic evaluation based on analysis of production records, validation of methods for genomic estimated breeding values,...and other contents.
108p
oursky05
20-09-2023
6
3
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Telomeres are DNA-protein complexes that cap chromosomal ends to promote chromosomal stability. Telomere length has been associated with diet and nutrition and inversely associated with mortality, life stress, and diseases. The objective of the current study was to explore the effect of long-term intake of multiple dietary supplements on telomere length in adults compared with age-matched controls.
6p
viisac
23-09-2023
3
1
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In this paper, the isolation and structural elucidation of three compounds: albifolione (1), zeorin (2), and atranorin (3) from the lichen P. cristiferum are reported. Their structures were elucidated from spectroscopic data and comparison with literature data.
6p
vinebula
02-06-2023
6
2
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Advances in next generation sequencing allow us to do DNA sequencing rapidly at a relatively low cost. Multiple bioinformatics methods have been developed to identify genomic variants from whole genome or whole exome sequencing data. The development of better variant calling methodologies is limited by the difficulty of assessing the accuracy and completeness of a new method.
7p
vicaptainmarvel
21-04-2023
5
2
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Several methods have been proposed to account for multiple comparisons in genetic association studies. However, investigators typically test each of the SNPs using multiple genetic models.
10p
vinarcissa
21-03-2023
2
1
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In this study, a single-trait genomic model (STGM) is compared with a multiple-trait genomic model (MTGM) for genomic prediction using conventional estimated breeding values (EBVs) calculated using a conventional single-trait and multiple-trait linear mixed models as the response variables.
7p
vinarcissa
21-03-2023
4
1
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This study provides comparative findings on the impact of adoption of International Financial Reporting Standards (IFRSs) on the value relevance of reported accounting and non-accounting information in a set of six countries with a British accounting heritage but divergent harmonization paths leading up to IFRS adoption. The countries included in the sample are the United Kingdom, Australia, Hong Kong, Singapore, Malaysia and South Africa.
229p
runthenight04
02-02-2023
6
2
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This book "Coding Projects in Python" is based on Python®, one of the world’s most widely used coding languages. Equally popular with students and professionals, Python is easy to pick up yet powerful and versatile. It’s a great language to learn whether you’re a beginner or moving up from a simple language like Scratch. Please refer to the content of part 1 of book.
109p
britaikridanik
05-07-2022
18
10
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Due to the fast-growing relapsed/refractory multiple myeloma (RRMM) treatment landscape, a comparison of all the available treatments was warranted. For clinical practice it is important to consider both immediate effects such as response quality and prolonged benefits such as progression-free survival (PFS) in a meta-analysis. The objective of this study was to assess the impact of the choice of outcome on the treatment rankings in RRMM.
12p
visusanwojcicki
28-06-2022
12
2
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SKESA is a DeBruijn graph-based de-novo assembler designed for assembling reads of microbial genomes sequenced using Illumina. Comparison with SPAdes and MegaHit shows that SKESA produces assemblies that have high sequence quality and contiguity, handles low-level contamination in reads, is fast, and produces an identical assembly for the same input when assembled multiple times with the same or different compute resources.
13p
vigalileogalilei
27-02-2022
13
1
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Chromatin folding gives rise to structural elements among which are clusters of densely interacting DNA regions termed topologically associating domains (TADs). TADs have been characterized across multiple species, tissue types, and differentiation stages, sometimes in association with regulation of biological functions.
18p
vigalileogalilei
27-02-2022
9
1
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Heterogeneity in single-cell RNA-seq (scRNA-seq) data is driven by multiple sources, including biological variation in cellular state as well as technical variation introduced during experimental processing.
20p
viarchimedes
26-01-2022
6
0
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Single-cell RNA sequencing has been widely adopted to estimate the cellular composition of heterogeneous tissues and obtain transcriptional profiles of individual cells. Multiple approaches for optimal sample dissociation and storage of single cells have been proposed as have single-nuclei profiling methods.
25p
viarchimedes
26-01-2022
6
0
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