Multiple testing correction

The research drew its data from 24 test papers submitted by teachers from three provinces in Vietnam. The findings revealed that a number of test items violated the principles, having unclear testing purposes or having more than correct answers while no needless redundancies in the stems and distractors were recorded. The paper concluded with several resolutions to address the issue.

6p vispacex 16-11-2023 6 4   Download

Linkage Disequilibrium (LD) is a powerful approach for the identification and characterization of morphological shape, which usually involves multiple genetic markers. However, multiple testing corrections substantially reduce the power of the associated tests.

8p vinarcissa 21-03-2023 6 1   Download

Expression quantitative trait loci (eQTL) mapping is a widely used tool to study the genetics of gene expression. Confounding factors and the burden of multiple testing limit the ability to map distal trans eQTLs, which is important to understand downstream genetic effects on genes and pathways.

13p viaristotle 29-01-2022 12 0   Download

Multiple hypothesis testing is a major issue in genome-wide association studies (GWAS), which often analyze millions of markers. The permutation test is considered to be the gold standard in multiple testing correction as it accurately takes into account the correlation structure of the genome.

18p viaristotle 29-01-2022 11 1   Download

One challenge facing omics association studies is the loss of statistical power when adjusting for confounders and multiple testing. The traditional statistical procedure involves fitting a confounder-adjusted regression model for each omics feature, followed by multiple testing correction.

18p viarchimedes 26-01-2022 11 0   Download

Epigenome-wide association studies (EWAS), which seek the association between epigenetic marks and an outcome or exposure, involve multiple hypothesis testing. False discovery rate (FDR) control has been widely used for multiple testing correction. However, traditional FDR control methods do not use auxiliary covariates, and they could be less powerful if the covariates could inform the likelihood of the null hypothesis.

19p viarchimedes 26-01-2022 10 1   Download

Selection of an appropriate statistical significance threshold in genome-wide association studies is critical to differentiate true positives from false positives and false negatives. Different multiple testing comparison methods have been developed to determine the significance threshold; however, these methods may be overly conservative and may lead to an increase in false negatives.

8p visilicon2711 20-08-2021 12 1   Download

In this study, we tested more than 170 surveys of nine different types. The software tool correctly detected all the valid answers. It was also able to detect all questions with no or multiple marks.

8p chauchaungayxua12 09-07-2021 11 1   Download

Gene set testing has become an important analysis technique in high throughput microarray and next generation sequencing studies for uncovering patterns of differential expression of various biological processes. Often, the large number of gene sets that are tested simultaneously require some sort of multiplicity correction to account for the multiplicity effect.

16p vikentucky2711 26-11-2020 13 1   Download

Transcriptomic approaches (microarray and RNA-seq) have been a tremendous advance for molecular science in all disciplines, but they have made interpretation of hypothesis testing more difficult because of the large number of comparisons that are done within an experiment.

13p viflorida2711 30-10-2020 11 2   Download

An important issue in microarray data is to select, from thousands of genes, a small number of informative differentially expressed (DE) genes which may be key elements for a disease. If each gene is analyzed individually, there is a big number of hypotheses to test and a multiple comparison correction method must be used.

20p viconnecticut2711 28-10-2020 28 1   Download

Để rèn luyện thêm từ vựng, học sinh có thể làm các chương từ I đến V ( Multiple choice Tests, Lexical Core Tests, open close Tests, Word fornation và Trios of Gapped Sentences). Các chương VI (Sentence Completion). VII (Sentence transformation) và VIII (Error Correction) dùng cho việc rèn luyện kĩ năng nhận biết cấu trúc câu.

129p vitsunade2711 02-06-2020 74 14   Download

A novel plasmid vector pSELECT-1 is described which can be used for highly efficient site-directed in vitro mutagenesis. The mutagenesis method is based on the use of single-stranded DNA and two primers, one mutagenic primer and a second correction primer which corrects a defect in the ampicillin resistance gene on the vector and reverts the vector to ampicillin resistance. Using T4 DNA polymerase and T4 DNA ligase the two primers are physically linked on the template. The non-mutant DNA strand is selected against by growth in the presence of ampicillin.

5p zingzing09 24-04-2013 55 4   Download

This paper describes a series of experiments to test the hypothesis that the parallel application of multiple NLP tools and the integration of their results improves the correctness and robustness of the resulting analysis. It is shown how annotations created by seven NLP tools are mapped onto toolindependent descriptions that are defined with reference to an ontology of linguistic annotations, and how a majority vote and ontological consistency constraints can be used to integrate multiple alternative analyses of the same token in a consistent way. ...

12p hongdo_1 12-04-2013 48 1   Download

The Investment Company Products/Variable Contracts Products Limited Representative Qualification Examination (Test Series 6) is a 100-question multiple-choice examination. A maximum of 135 minutes testing time is allowed for candidates to complete the examination. The passing grade is equal to 70% of the total number of questions on the examination. Candidates will be required to correctly answer 70 of the 100 questions on the examination to receive a passing grade.

206p haiduong_1 03-04-2013 61 9   Download

Since such a fund is determined according to a pre-ranking of all fund alphas, a correct inference about its alpha must take into account the entire cross-section of the fund alphas3. In this context, they advocate to use a bootstrap procedure, and conclude that they account for luck in the sense that they correctly compute the p-values of the individual funds4. This definition of luck is not related to the issue of multiple testing investigated in this paper.

301p dangsuynghi 15-03-2013 53 8   Download

Ensure that system and network administrators are trained and capable. Security testing must be performed by capable and trained staff. Often, individuals recruited for this task are already involved in system administration. While system administration is an increasingly complex task, the numbers of trained system administrators generally has not kept pace with the increase in computing systems.

41p cao_can 02-01-2013 71 6   Download

The Program Management Professional (PgMP®) Exam Practice Test & Study Guide includes five sections, each of which corresponds to one of the five domains described in the Program Management Professional (PgMP®) Examination Content Outline (April 2011). Each section contains study hints, a list of major topics that are encountered on the exam, and 20 multiple-choice practice questions complete with an answer sheet, an answer key that includes a rationale for each correct answer, and a bibliographic reference for further study if needed.

428p baobinh1311 25-09-2012 136 16   Download

Subjective & Objective terms the scoring methods All tests subjectively constructed by the test writer Objective tests: only one correct answer. + scored mechanically by computer + responsible for testing a large number of candidates

16p namson94 20-07-2012 85 6   Download

Start Testing Your Vocabulary (Beginner-Elementary, 850 words) - book in the series «Test Your», which contains 60 different levels of tests on various vocabulary themes.Different types of tests: gap-fills, multiple-choice, crosswords, puzzles, correcting misprints, picture tests, etc. Answers to all tests - at the end of the book.

91p tiendat_1592 01-11-2011 270 163   Download