Murine mammary tumor
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Osteopontin is a secreted phosphoglycoprotein that is expressed by a number of normal cells as well as a variety of tumor cells. With respect to breast cancer, osteopontin has been implicated in regulating tumor cell proliferation and migration/metastasis and may serve as a prognostic indicator.
11p vinaypyidaw2711 26-08-2020 11 2 Download
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Endurance training slows breast tumor growth in mice by suppressing Treg cells recruitment to tumors
Aerobic exercise has been shown to slow tumor progression in rodents and humans, but the mechanisms behind this effect are still unclear. Here we show that aerobic exercise in the form of chronic endurance training suppresses tumor recruitment of FoxP3+ Treg cells thus enhancing antitumor immune efficiency.
10p vikuala271 13-06-2020 11 0 Download