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Murine model infected
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Enrofloxacin is an antibacterial drug with broad-spectrum activity that is widely indicated for veterinary use. We aim to develop the clinical applications of Enrofloxacin against colibacillosis by using the neutropenic mice thigh infection model.
13p
vidarwin
23-02-2022
8
1
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During initial characterization, we observed significant reproductive cycle-based variation in infection outcome. When uterine infection occurred in the diestrus phase, there was significantly greater pathology than during estrus phase. The aim of this study was to evaluate transcriptional profiles of infected uterine tissue from mice in either estrus or diestrus phase in order to elucidate possible mechanisms for these differences.
19p
vitzuyu2711
29-09-2021
11
1
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Ataxia telangiectasia (A-T) is a rare but devastating and progressive disorder characterized by cerebellar dysfunction, lymphoreticular malignancies and recurrent sinopulmonary infections. In A-T, disease of the respiratory system causes significant morbidity and is a frequent cause of death.
9p
vimontana2711
05-04-2021
5
1
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Human infection with avian influenza A virus (H7N9) was first reported in China in March 2013. Since then, hundreds of cases have been confirmed showing severe symptoms with a high mortality rate.
12p
vihamax2711
21-04-2020
5
1
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The aim of present study was to express the microneme 10 (MIC10) antigenic protein which is a circulating antigen following invasion by tachyzoites in hosts in the prokaryotic expression system and evaluated as a potential diagnostic marker by indirect ELISA using the infected and non infected sera samples from Swiss albino mice. Optimum working dilutions of the antigen, sera and the conjugate were determined by checker board titrations and the cut off value was generated as mean plus standard deviation of optical densities of negative sera by ELISA.
10p
quenchua4
06-04-2020
19
2
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The azoxymethane (AOM)/dextran sulfate sodium (DSS) murine model is commonly used to study colitis-associated cancer. The human commensal bacterium, enterotoxigenic Bacteroides fragilis (ETBF) secretes the Bacteroides fragilis toxin (BFT) which is necessary and sufficient to cause colitis.
8p
vivalletta2711
11-01-2020
9
0
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The in vitro antimicrobial potency of the bacteriocin AS-48 is well documented, but its clinical application requires investigation, as its toxicity could be different in in vitro (haemolytic and antibacterial activity in blood and cytotoxicity towards normal human cell lines) and in vivo (e.g. mice and zebrafish embryos) models. Overall, the results obtained are promising.
11p
trinhthamhodang1
14-11-2019
18
1
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