Mycobacterium tuberculosis in PLHIV

HIV and TB co-infection is an alarming situation in the health care system. India has the third largest number of people living with HIV (PLHIV) in the world. This co-infection leads to difficulty in both diagnosis and treatment of TB resulting in increased mortality, morbidity, treatment failure and relapse. The present study was conducted to determine the prevalence of TB in PLHIV and also to determine its co-relation with the CD4 counts of the affected individuals. This is a prospective study conducted over a period of one year commencing from April 2017 to March 2018.

6p trinhthamhodang3 12-02-2020 12 1   Download

Pulmonary system is the most commonly involved system in people living with HIV as lungs are continuously exposed to the infection as they are rich in macrophages, dendritic cells, lymphocytes etc. In PLHIV immunity is suppressed, hence lungs are prone for infection and non infectious pulmonary diseases. According to autopsy findings, in HIV lung was affected almost upto 100% in the period of epidemic to 70% in the HAART era. Pneumonia is most common pulmonary manifestation followed by pulmonary tuberculosis and PCP.

4p trinhthamhodang3 12-02-2020 19 0   Download