![](images/graphics/blank.gif)
Natural killer
-
Adoptive cell therapy has achieved great success in treating hematological malignancies. However, the production of chimeric antigen receptor T (CAR-T) cell therapy still faces various difficulties. Natural killer (NK)-92 is a continuously expandable cell line and provides a promising alternative for patient’s own immune cells.
12p
vishanshan
27-06-2024
2
1
Download
-
Despite the utilization of immune checkpoint inhibitors (ICIs) in treating numerous types of cancers being approved, their efficacy in tumor control in the clinic is not satisfactory. Since adoptive cell therapy (ACT) can alter the tumor microenvironment, we hypothesized that ACT potentially synergized with ICI in tumor control and examined this hypothesis via a murine allograft model.
11p
vikoch
27-06-2024
1
1
Download
-
Ebook "Current topics in innate immunity II" compiles the latest advances in this rapidly evolving field as presented by eminent scientists at the 7th International Aegean Conference on Innate Immunity in Rhodes, Greece. It includes topics related to the biology and function of Toll-like and other pattern-recognition receptors, complement and its crosstalk with other physiological systems, inflammatory mechanisms and diseases, natural killer cells, and the cooperative interplay between innate and adaptive immune cells.
357p
ladongphongthanh1008
22-04-2024
6
3
Download
-
Influenza infects tens of millions of people every year in the USA. Other than notable risk groups, such as children and the elderly, it is difficult to predict what subpopulations are at higher risk of infection. Viral challenge studies, where healthy human volunteers are inoculated with live influenza virus, provide a unique opportunity to study infection susceptibility.
12p
vibransone
28-03-2024
9
2
Download
-
Extranodal, natural-killer/T-cell lymphoma of nasal type is a rare but aggressive disease usually presenting as progressive necrotic lesions in the nasal cavity that responds poorly to chemotherapy. In this paper, we report a relapsing, chemorefractory case of extranodal natural-killer/T-cell lymphoma responding to checkpoint inhibitor immunotherapy with pembrolizumab.
7p
vilazada
31-01-2024
2
2
Download
-
Owing to non-responsiveness of a high number of patients to the common melanoma therapies, seeking novel approaches seem as an unmet requirement. Chimeric antigen receptor (CAR) T cells were initially employed against recurrent or refractory B cell malignancies.
9p
vileonardodavinci
23-12-2023
2
2
Download
-
Sorafenib inhibits interferon production by plasmacytoid dendritic cells in hepatocellular carcinoma
Sorafenib is a multi-kinase inhibitor that shows antitumor activity in advanced hepatocellular carcinoma. Sorafenib exerts a regulatory effect on immune cells, including T cells, natural killer cells and dendritic cells.
7p
vileonardodavinci
23-12-2023
3
2
Download
-
Other iatrogenic immunodeficiency-associated (OIIA) T- and natural killer (NK)-cell lymphoproliferative disorders (TNK-LPDs) are rare in patients with rheumatoid arthritis (RA). We investigated the clinicopathological characteristics, Epstein–Barr virus (EBV) infection, genetic findings, therapeutic response, and prognostic factors in 21 RA patients with OIIA TNK-LPDs and compared these with those of 39 with OIIA B-cell LPDs (B-LPDs) and 22 with non-OIIA B-LPDs.
14p
vileonardodavinci
23-12-2023
5
2
Download
-
Increasing evidence has convincingly shown that abnormal pre-mRNA splicing is implicated in the development of most human malignancies. Serine/arginine-rich protein kinase 1 (SRPK1), a key splicing regulator, is reported to be overexpressed in leukemia and other cancer types, which suggests the therapeutic potential of targeting SRPK1.
13p
vileonardodavinci
23-12-2023
5
3
Download
-
A new type of immune cell transplantation called allogeneic NK cell infusion is proposed as a potential universal off-the-shelf cell product for adoptive immune cell therapy in hematologic malignancies.
10p
vileonardodavinci
23-12-2023
3
2
Download
-
Tregs are able of suppressing tumor-specific efector cells, such as lymphocytes CD8+, CD4+ and Natural Killer cells. Different drugs, especially different schedules of administration, like metronomic chemotherapy (mCHT), seem to be able to increase anticancer immunity, by acting on downregulation of Tregs.
10p
vialfrednobel
23-12-2023
5
3
Download
-
Part 1 book "Parasites and infectious disease" includes content: African trypanosomes and their VSGs, malaria - the real killer, the HIV - AIDS vaccine and the disadvantage of natural selection - the yellow fever vaccine and the advantage of artificial selection, lyme disease - a classic emerging disease.
185p
muasambanhan01
13-12-2023
10
3
Download
-
Bài viết trình bày việc thiết lập quy trình tinh sạch tế bào giết tự nhiên (natural killer - NK) và quy trình nuôi cấy tăng sinh tạo khối tế bào NK của bệnh nhân (BN) ung thư tuyến tiền liệt (UTTTL) trong phòng thí nghiệm.
10p
vishekhar
31-10-2023
6
2
Download
-
Thermal therapy induces an immune response in patients with hepatocellular carcinoma (HCC), but the dynamic characteristics of the natural killer (NK) cell immune response post-thermal ablation remain unclear.
14p
vischultz
20-10-2023
1
1
Download
-
To study Natural Killer (NK) cell activity (NK-IFNγ) and some indicators related to immunological characteristics of peripheral blood NK cells in healthy people and breast cancer patients.
11p
viwolverine
07-07-2023
4
1
Download
-
Bài viết Khảo sát sự thay đổi các tế bào lympho và tế bào diệt tự nhiên NK máu ngoại vi ở bệnh nhân viêm phổi tại Bệnh viện Nhi Trung ương bước đầu khảo sát sự thay đổi tế bào lympho T và dưới nhóm, tế bào lympho B và tế bào diệt tự nhiên (Natural Killer – NK) máu ngoại vi trong viêm phổi ở trẻ em.
4p
videadpool
05-05-2023
5
3
Download
-
To evaluate the effect of regorafenib on soluble MHC class I polypeptide-related sequence A (MICA) (sMICA) level in vitro. In addition, we clinically examined whether its plasma levels were associated with regorafenib activity in terms of progression-free survival (PFS) in patients with CRC.
10p
vikolindagrabar
27-07-2022
3
1
Download
-
Extranodal natural killer/T cell lymphoma (NKTCL) is a highly aggressive type of non-Hodgkin lymphoma that facing the treatment challenges. Natural compounds are important sources for drug development because of their diverse biological and chemical properties, among which terpenoids have strong anticancer activities.
10p
vikolindagrabar
27-07-2022
3
1
Download
-
Natural killer (NK) cells-based therapies are one of the most promising strategies against cancer. The aim of this study is to investigate the natural killer cell-related genes and its prognostic value in glioma.
12p
vipriyankagandhi
27-07-2022
3
3
Download
-
Bài giảng Mô tả trường hợp tăng sinh tế bào lympho liên quan nhiễm sắc thể X type 1 ở bệnh nhân nam 2 tuổi tại Bệnh viện Nhi Đồng I do Ths.BS. Cao Trần Thu Cúc biên soạn trình bày mô tả triệu chứng lâm sàng, cận lâm sàng và theo dõi điều trị bệnh nhân nam 2 tuổi mang đột biến gen SH2D1A gây bệnh tăng sinh tế bào lympho liên quan nhiễm sắc thể X type 1.
16p
vileonardodavinci
11-03-2022
18
2
Download
CHỦ ĐỀ BẠN MUỐN TÌM
![](images/graphics/blank.gif)