Natural naphthoquinone

Shikonin, a natural naphthoquinone, is abundant in Chinese herb medicine Zicao (purple gromwell) and has a wide range of biological activities, especially for cancer. Shikonin and its analogues have been reported to induce cell-cycle arrest, but target information is still unclear.

9p viputrajaya2711 22-06-2020 5 0   Download

The antimalarial activity of plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone), a naturally occurring naphthoquinone widely distributed in the Plumbaginaceae family has previously been demonstrated in vitro (good activity) and in vivo (weak activity).

10p vienzym2711 30-03-2020 13 1   Download

Naturally occurring pyranonaphthoquinones are of special interest due to their important physiological activities. In continuation of our synthetic efforts towards physiologically active psychorubrin derivatives, we now report here a convenient synthesis of psychorubrin derivatives in four steps with a good yield from 1,4- naphthoquinone.

5p uocvong04 24-09-2015 27 3   Download