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Neoplastic disease

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  • Appendiceal Mucocele (AM) is a very rare disease, believed to be more common in middle-aged women, and includes both non-neoplastic and neoplastic lesions. If not diagnosed and treated early, it can lead to mucin leakage, spilling into the peritoneal cavity, resulting in severe consequences, particularly the complication of pseudomyxoma peritonei (PMP), which has a very poor prognosis.

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  • Among the subspecialties of internal medicine, medical oncology may have had the greatest impact in changing the practice of medicine in the past four decades, as curative treatments have been identified for a number of previously fatal malignancies such as testicular cancer, lymphomas, and leukemia. New drugs have entered clinical use for disease presentations previously either untreatable or amenable to only local means of therapy, such as surgery and irradiation.

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  • Harrison's Internal Medicine Chapter 104. Acute and Chronic Myeloid Leukemia Acute and Chronic Myeloid Leukemia: Introduction The myeloid leukemias are a heterogeneous group of diseases characterized by infiltration of the blood, bone marrow, and other tissues by neoplastic cells of the hematopoietic system. In 2006 the estimated number of new myeloid leukemia cases in the United States was 16,430. These leukemias comprise a spectrum of malignancies that, untreated, range from rapidly fatal to slowly growing.

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  • Neoplastic disease In most cases, the cause of cancer is multifactorial. About 75% of cancers are due to environmental factors, some of which are within the control of the individual, e.g. tobacco smoking, exposure to sunlight. Growing understanding of cancer genetics and inherited disease suggests that fewer than 10% of cancers are familial.The different systemic modalities used to treat cancer patients are discussed. Immunosuppressive drugs are described here as they share many characteristics with cytotoxics. ...

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