Neural stem cells

Ebook "Neural stem cells in development, adulthood and disease" is the first to specifically target developing, adult and diseased neural stem cells. It explores recent advances in the understanding of neural stem cell biology along with strategies that use these cells to tackle neurological diseases and brain aging. Ten inclusive chapters discuss a wide range of topics including neurogenesis, neurodegeneration, demyelinating disease, mood regulation, and spinal cord regeneration, among others.

219p ladongphongthanh1008 22-04-2024 1 1   Download

Ebook "Prominin-1 (CD133): New insights on stem & cancer stem cell biology" was conceived to celebrate the fi fteenth anniversary of the discovery of prominin-1, also known in the medical fi eld as CD133. This book is composed of 15 chapters that will describe, on one hand, the molecular and cellular biology of prominin-1 and other members of the prominin family and, on the other hand, the importance of this molecule in the medical fi eld as a valuable marker of stem and cancer stem cells.

255p tracanhphuonghoa1007 22-04-2024 3 1   Download

Ebook "Adult stem cells: Biology and methods of analysis" offers readers a historical perspective as well as unique insights into cutting-edge thoughts. The volume contextualizes the recent discovery of stem/progenitor cell populations resident in many adult tissues and organs. It confronts the complexities scientists face in trying to validate these cells, while it also describes and critically evaluates the methods currently used to assess stem cell self-renewal.

282p tracanhphuonghoa1007 22-04-2024 4 2   Download

Ebook "Induced pluripotent stem cells in brain diseases: Understanding the methods, epigenetic basis, and applications for regenerative medicine" discusses the various methods to reprogram cells, the control and determination of cell identity, the epigenetic models that have emerged and the application of iPS cell therapy for brain diseases, in particular Parkinson’s disease and Vanishing White Matter (VWM).​

69p tachieuhoa 28-01-2024 2 2   Download

Ebook "Modeling fragile X syndrome" introduction to probing astrocyte function in fragile X syndrome; neural stem cells; fragile X mental retardation protein (FMRP) and the spinal sensory system; the role of the postsynaptic density in the pathology of the fragile X syndrome; behavior in a drosophila model of fragile X; molecular and genetic analysis of the drosophila model of fragile X syndrome;...

384p tachieuhoa 28-01-2024 4 2   Download

Ebook "Autophagy in health and disease: Potential therapeutic approaches" cover autophagy and its potential applications on diseases ranging from obesity, osteoarthritis, pulmonary fibrosis, and inflammation, through ALS, Parkinson's, retinal degeneration, breast cancer, alcoholic liver disease and more. The final chapters round out the book with a discussion of autophagy in drug discovery and 'bench to bedside'.

182p lamquandat 28-12-2023 3 2   Download

Ebbok "Advances in stem cell therapy: Bench to bedside" reviews the main approaches for generation of differentiated cells from various types of stem cells, including embryonic, placental and cord blood stem cells through marrow, adipose tissue and dental pulp. The book starts with an overview of experimental protocols applied to generate insulin secreting cells, neural cells, heart cells, and other tissue specific cells ex vivo and in experimental animals.

319p lamquandat 28-12-2023 3 2   Download

Ebook "Neural cell biology" delineates how systems biology, pharmacogenomic, and behavioral approaches, as applied to neurodevelopmental toxicology, provide a structure to arrange information in a biological model. The text　reviews and　discusses approaches that can be used as effective tools to dissect mechanisms underlying pharmacological and toxicological phenomena associated with the exposure to drugs or environmental toxicants during development.

348p lucchinguyen 28-12-2023 7 2   Download

The neural stem/precursor cells (NSCs) in the ventricular-subventricular zone (V-SVZ) contribute to adult neurogenesis and gliogenesis, however, the mechanisms regulating NSC phenotype and functions remain to be elucidated.

7p visoros 01-11-2023 6 1   Download

The purification of extracellular vesicles (EVs) remains a major hurdle in the progression of fundamental research and the commercial application of EV-based products. In this study, we evaluated the potential of heparin affinity chromatography (HAC) to purify neural stem cell-derived EVs as part of a multistep process.

16p viginny 23-12-2022 6 3   Download

Obesity is a complicated metabolic malfunction linked to disconnected signaling between interorgans, and inter-molecularly affected by impairment of the neuronal circuit, stemming from environmental stressors in children and adults. Upon environmental intoxication or change in the surrounding environmental stressors; the signaling for hunger could affect regulatory signaling in energy consumption and lead to a wide range of metabolic disruption and sensitivity, cell-to-cell and organ-to-organ.

6p viporsche 28-10-2022 8 2   Download

At present, sevoflurane inhalation anesthesia used on infants is well-known. But long-time exposure to inhalation anesthetic could cause neurologic disorder, especially nerve degeneration in infant and developing brain. The central nervous system degeneration of infants could affect the memory and cognitive function. γ-Aminobutyric acid (GABA) is a known inhibitory neurotransmitter in central nervous system.

8p viisaacnewton 26-04-2022 9 1   Download

Propofol is a widely used intravenous anesthetic that is well-known for its protective effect in various human and animal disease models. However, the effects of propofol on neurogenesis, especially on the development of neural stem cells (NSCs), remains unknown. Related microRNAs may act as important regulators in this process.

11p viottohahn 30-03-2022 8 1   Download

Glioma stem cells (GSCs) are a subpopulation of stem-like cells that contribute to glioblastoma (GBM) aggressiveness, recurrence, and resistance to radiation and chemotherapy. Therapeutically targeting the GSC population may improve patient survival, but unique vulnerabilities need to be identified.

25p vimichaelfaraday 25-03-2022 21 1   Download

The ability of adipose tissue-derived multipotent mesenchymal stromal cells/mesenchymal stem cells (ASCs) to differentiate in neural lineages promises progress in the field of regenerative medicine, especially for replacing neuronal tissue damaged by different neurological disorders.

12p vigandhi 23-02-2022 28 1   Download

The planarian Schmidtea mediterranea is a master regenerator with a large adult stem cell compartment. The lack of transgenic labeling techniques in this animal has hindered the study of lineage progression and has made understanding the mechanisms of tissue regeneration a challenge. However, recent advances in single-cell transcriptomics and analysis methods allow for the discovery of novel cell lineages as differentiation progresses from stem cell to terminally differentiated cell.

17p viaristotle 29-01-2022 9 0   Download

The neural crest (NC) is a class of transitory stem cell-like cells unique to vertebrate embryos. NC cells arise within the dorsal neural tube where they undergo an epithelial to mesenchymal transition in order to migrate and differentiate throughout the developing embryo. The derivative cell types give rise to multiple tissues, including the craniofacial skeleton, peripheral nervous system and skin pigment cells.

13p vibeauty 23-10-2021 9 0   Download

There is increasing evidence of a pivotal role for regulated mRNA translation in control of developmental cell fate transitions. Physiological and pathological stem and progenitor cell self-renewal is maintained by the mRNA-binding protein, Musashi1 through repression of translation of key mRNAs encoding cell cycle inhibitory proteins.

9p viwyoming2711 16-12-2020 9 1   Download

Human dental pulp represents a suitable alternative source of stem cells for the purpose of cell-based therapies in regenerative medicine, because it is relatively easy to obtain it, using low invasive procedures. This study characterized and compared two subpopulations of adult stem cells derived from human dental pulp (hDPSCs).

16p viwyoming2711 16-12-2020 9 1   Download

The RNA polymerase II transcriptional Mediator subunit Med12 is broadly implicated in vertebrate brain development, and genetic variation in human MED12 is associated with X-linked intellectual disability and neuropsychiatric disorders.

15p viwyoming2711 16-12-2020 8 0   Download