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Neuromuscular blockade
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Part 2 book "The ventilator book - First draught press" includes content: Trigger and flow, patient ventilator dyssynchrony, severe bronchospasm and hyperinflation, prone positioning and neuromuscular blockade, airway pressure release ventilation, inhaled pulmonary vasodilators, high frequency oscillatory ventilation, veno venous ECMO, veno-arterial ECMO, liberation from mechanical ventilation, prolonged respiratory failure, mechanical ventilation during a pandemic or mass casualty event, seven rules for severe respiratory failure, ventilator flowsheets and guidelines.
154p
oursky07
24-10-2023
6
2
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Part 1 book "Anesthesiology" includes content: Evolution of anesthesiology as a clinical discipline - A lesson in developing professionalism, overview of preoperative assessment and management, the anesthetic plan for healthy patients, preoperative assessment of newborns and children, appropriate and effective use of consultants,.... and other contents.
350p
oursky06
13-10-2023
2
2
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Part 2 book "Anesthesiology" includes content: Perioperative information management systems, hemodynamic monitoring, intraoperative transesophageal echocardiography - a systematic approach, monitoring respiratory function, intraoperative neurologic monitoring, monitoring and managing neuromuscular blockade,.... and other contents.
844p
oursky06
13-10-2023
7
2
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Part 2 book "Miller's anesthesia" includes content: Pharmacology of neuromuscular blocking drugs; reversal (antagonism) of neuromuscular blockade, local anesthetics; local anesthetics local anesthetics, anesthetic implications of concurrent diseases, anesthetic implications of complementary and alternative therapies.
1215p
oursky01
24-07-2023
6
2
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Test ventilating prior to administration of neuromuscular blockade (NMB) in order to avoid a cannot intubate-cannot ventilate situation is a classic anesthesia teaching. The primary aim of our study was to show that facemask ventilation (FMV) after NMB was not inferior to FMV prior to NMB with respect to exhaled gas volumes before and after their administration.
9p
viisaacnewton
25-04-2022
10
1
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Deep neuromuscular blockade may be beneficial on surgical space conditions during laparoscopic surgery. The effects of moderate neuromuscular blockade combined with transverse abdominal plane block (TAPB) on surgical space conditions during laparoscopic surgery have not been described.
9p
viisaacnewton
26-04-2022
6
1
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This study compared efficacy and safety of the selective relaxant binding agent sugammadex (2 mg/kg) with neostigmine (50 μg/kg) for neuromuscular blockade (NMB) reversal in Chinese and Caucasian subjects.
10p
viisaacnewton
26-04-2022
5
1
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The effectiveness of sugammadex in reversing rocuronium-induced neuromuscular blockade (NMB) in the presence of drugs that may potentiate NMB remains to be fully established. The aim of this post-hoc analysis of data from a Phase III clinical trial (VISTA; NCT00298831) was to investigate the impact of antibiotics on recovery from rocuronium-induced NMB after administration of sugammadex for reversal, and compared the neuromuscular recovery in patients who received antibiotics preoperatively with those who did not.
5p
viisaacnewton
26-04-2022
6
1
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Mild hypothermia may be frequently induced due to cool environments in the operating room. The study analyzed patient recovery time and response to sugammadex after a prolonged rocuronium-induced deep neuromuscular block (NMB) during mild hypothermia.
6p
viisaacnewton
26-04-2022
13
1
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Sugammadex reverses the effect of rocuronium more rapidly and effectively than neostigmine, at all levels of neuromuscular blockade (NMB). However, its cost is prohibitive. The combination of half dose sugammadex with neostigmine would be non-inferior to full dose sugammadex for the reversal of deep NMB. This approach would reduce the cost of sugammadex while preserving its efficacy.
7p
viottohahn
30-03-2022
5
1
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A moderate insufflation pressure and deep neuromuscular blockade (NMB) have been recommended in laparoscopic surgery in consideration of the possible reduction in splanchnic perfusion due to the CO2-pneumoperitoneum.
9p
viottohahn
30-03-2022
10
1
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The objective of this analysis is to explore potential impact on operating room (OR) efficiency and incidence of residual neuromuscular blockade (RNMB) with use of sugammadex (Bridion™, Merck & Co., Inc., Kenilworth, NJ USA) versus neostigmine for neuromuscular block reversal in Canada.
12p
viottohahn
30-03-2022
7
1
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Laparoscopic surgery typically requires deep neuromuscular blockade (NMB), but whether deep or moderate NMB is superior for thoracoscopic surgery remains controversial. Methods: Patients scheduled for thoracoscopic lobectomy under intravenous anesthesia were randomly assigned to receive moderate [train of four (TOF) 1–2] or deep NMB [TOF 0, post-tetanic count (PTC) 1–5].
10p
vampires36
30-12-2021
8
0
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Neuromuscular blocking drugs (NMBD) are administered intra-operatively to facilitate intubation and to achieve muscle relaxation for surgical procedures. Incomplete reversal of NMBD can lead to adverse events in the postoperative period. Patients with obstructive sleep apnea (OSA) may be at higher risk of complications related to the use of NMBD.
11p
vampires36
30-12-2021
12
0
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The Supreme™ and ProSeal™ laryngeal mask airways (LMAs) are widely used in paediatric anaesthesia; however, LMA use in infants is limited because many anaesthesiologists prefer to use tracheal intubation in infants. In this study, we compared the Supreme and ProSeal LMAs in infants by measuring their performance characteristics, including insertion features, ventilation parameters, induced changes in haemodynamics and rates of postoperative complications.
6p
vampires36
30-12-2021
10
0
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Hyperthermia is relatively rare during general anesthesia; however, a few studies have been conducted on hyperthermia and the neuromuscular blockade (NMB) induced by rocuronium, and the reversal of NMB by sugammadex. We investigated the effect of hyperthermia status on the NMB induced by rocuronium, and its reversal by sugammadex, in isolated phrenic nerve hemidiaphragm (PNHD) preparations of the rat.
7p
vizhangzhidong
29-12-2021
10
0
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Sugammadex is a modified gamma-cyclodextrin that acts by selectively encapsulating free aminosteroidal neuromuscular relaxants. Several case reports have been published on the use of sugammadex in patients with neuromuscular disorders that include neuromuscular junction diseases, myopathies, neuropathies, and motor neurone disorders. The primary aim of this review is to systematically review the evidence on the use of sugammadex in patients with this heterogeneous group of diseases and provide recommendations for clinical practice.
18p
vizhangzhidong
29-12-2021
37
0
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Sugammadex allows rapid recovery from rocuronium-induced neuromuscular blockade. Succinylcholine is often used for brief surgeries but is associated with myalgia, headache, histamine release, and increased lactate levels. Thus, we hypothesized that succinylcholine may affect emergence agitation (EA) and compared the effects of succinylcholine and rocuronium-sugammadex on EA in patients undergoing closed reduction of a nasal bone fracture under general anesthesia.
7p
vizhangzhidong
29-12-2021
13
0
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This study was designed to examine whether severe aortic regurgitation will affect the pharmacodynamics (PD) and pharmacokinetics (PK) of cisatracurium during anesthetic induction. Methods: A total of 32 patients were divided into two groups: the AR group (n = 16) and the control group (n = 16).
6p
vizhangzhidong
29-12-2021
9
0
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Reversing a neuromuscular blockade agent with sugammadex is known to lessen postoperative complications by reducing postoperative residual curarization. However, its effects on 90-day mortality are unknown. Therefore, this study aimed to compare the effects of sugammadex and neostigmine in terms of 90-day mortality after non-cardiac surgery.
11p
vizhangzhidong
29-12-2021
15
0
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