Next direction

Intertumoral heterogeneity represents a significant hurdle to identifying optimized targeted therapies in gastric cancer (GC). To realize precision medicine for GC patients, an actionable gene alteration-based molecular classification that directly associates GCs with targeted therapies is needed.

12p vioraclene 31-03-2024 5 2   Download

This research provides an analysis of the disparate notions and ideas, to form an overview of the possible trends in residential property for the Victorian coastal areas of the Surf Coast and the Bellarine Peninsula. It examines the interaction of the consumers, space producers and infrastructure providers as they are influenced by the three key determinants of the market, the demographic factors, economic conditions and statutory factors.

136p runthenight07 01-03-2023 4 3   Download

The main objectives of this study are: To provide an end-to-end channel model which is capable of supporting the dynamics of 5G networks based on Amplify-and-Forward UAV relays in the mmWawe band; to determine the optimum Amplify-and-Forward UAV relay height for coverage maximization in randomly distributed users scenarios; to compare the performance of the direct path (between the gNB and UE) with respect to the relay path (between the gNB and UE via UAV).

72p runthenight04 02-02-2023 4 1   Download

Marek’s disease (MD) is a highly neoplastic disease primarily affecting chickens, and remains as a chronic infectious disease that threatens the poultry industry. Copy number variation (CNV) has been examined in many species and is recognized as a major source of genetic variation that directly contributes to phenotypic variation such as resistance to infectious diseases.

12p vihagrid 30-01-2023 5 3   Download

Transcription factors (TFs) control gene expression by direct binding to regulatory regions of target genes but also by impacting chromatin landscapes and modulating DNA accessibility for other TFs. In recent years several TFs have been defined that control cell fate decisions and effector functions in the immune system.

20p vihagrid 30-01-2023 6 3   Download

The day-to-next day predictions between physical activity (PA) and sleep are not well known, although they are crucial for advancing public health by delivering valid sleep and physical activity recommendations. We used Big Data to examine cross-lagged time-series of sleep and PA over 14 days and nights.

7p viferrari 28-11-2022 12 2   Download

Lecture Electronic materials - Chapter 11: How do they work? (postponing the math) provide students with knowledge about A p-n junction diode is made by forming a p-type region of material directly next to a n-type region.

10p trollhunters 10-01-2022 12 0   Download

Sample index cross-talk can result in false positive calls when massively parallel sequencing (MPS) is used for sensitive applications such as low-frequency somatic variant discovery, ancient DNA investigations, microbial detection in human samples, or circulating cell-free tumor DNA (ctDNA) variant detection. Therefore, the limit-of-detection of an MPS assay is directly related to the degree of index cross-talk.

10p vibeauty 23-10-2021 9 1   Download

Numerous protocols for viral enrichment and genome amplification have been created. However, the direct identification of viral genomes from clinical specimens using next-generation sequencing (NGS) still has its challenges. As a selected viral nucleic acid extraction method may determine the sensitivity and reliability of NGS, it is still valuable to evaluate the extraction efficiency of different extraction kits using clinical specimens directly.

8p vitzuyu2711 29-09-2021 4 1   Download

"Petro Vietnam Journol Vol 6/2021" present Transport of oil/water partitioning components during water injection; An overview of the gasohol market in Vietnam, the next direction; Comparative analysis of financial assurance instruments for offshore oil decommissioning and mine restoration; Screening selection of enhanced oil recovery methods based on analytics of worldwide oilfield data with reference to offshore oil fields in Vietnam...

76p trinhthamhodang1220 21-07-2021 19 1   Download

Gene targeting by homology-directed repair (HDR) can precisely edit the genome and is a versatile tool for biomedical research. However, the efficiency of HDR-based modification is still low in many model organisms including zebrafish.

12p vijeeni2711 24-07-2021 10 0   Download

This paper presents an overview of the current state of Vietnam's gasohol market and a brief analysis of policy, supply - demand - price information, from which some hindrances are identified and a few more optimistic directions to develop this type of fuel in the future are proposed.

8p trinhthamhodang1220 21-07-2021 5 1   Download

In recent years, optical orthogonal frequency division multiplexing (OOFDM) has emerged as a dominant research and development area in the field of high-speed optical communications. OFDM is a potential candidate as the most promising next-generation optical networks such as passive optical networks and optical transport networks, due to their simple configuration based on low cost, high speed data rates, high spectral efficiency, high quality of service and robustness against narrow band interference, frequency selective fading, and chromatic dispersion.

99p nguathienthan12 18-05-2021 17 6   Download

Cancer of unknown primary (CUP) is usually treated with nonselective and empirical chemotherapy; however, its prognosis is generally poor, with a median survival of less than a year. Thus, clinicians eagerly await the development of more effective treatment strategies.

5p vichaeng2711 29-04-2021 9 3   Download

An Interior-point algorithm with a line-search globalization is proposed for solving the general nonlinear programming problem. At each iteration, the search direction is obtained as a resultant of two orthogonal vectors. They are obtained by solving two square linear systems. An upper-triangular linear system is solved to obtain the Lagrange multiplier vector. The three systems that must be solved each iteration are reduced systems obtained using the projected Hessian technique. This fits well for large-scale problems.

16p nguaconbaynhay11 07-04-2021 14 1   Download

The amount of non-unique sequence (non-singletons) in a genome directly affects the difficulty of read alignment to a reference assembly for high throughput-sequencing data. Although a longer read is more likely to be uniquely mapped to the reference genome, a quantitative analysis of the influence of read lengths on mappability has been lacking.

12p viwyoming2711 16-12-2020 13 1   Download

Knockdown or overexpression of genes is widely used to identify genes that play important roles in many aspects of cellular functions and phenotypes. Because next-generation sequencing generates high-throughput data that allow us to detect genes, it is important to identify genes that drive functional and phenotypic changes of cells.

14p vikentucky2711 26-11-2020 5 0   Download

Gene set testing has become an important analysis technique in high throughput microarray and next generation sequencing studies for uncovering patterns of differential expression of various biological processes. Often, the large number of gene sets that are tested simultaneously require some sort of multiplicity correction to account for the multiplicity effect.

16p vikentucky2711 26-11-2020 13 1   Download

Somatically acquired structure variations (SVs) and copy number variations (CNVs) can induce genetic changes that are directly related to tumor genesis. Somatic SV/CNV detection using next-generation sequencing (NGS) data still faces major challenges introduced by tumor sample characteristics, such as ploidy, heterogeneity, and purity.

6p vikentucky2711 26-11-2020 29 1   Download

Amplicon re-sequencing based on the automated Sanger method remains popular for detection of single nucleotide polymorphisms (SNPs) and insertion-deletion polymorphisms (InDels) for a spectrum of genetics applications.

8p vioklahoma2711 19-11-2020 6 1   Download