Non-invasive methods

Many recent studies have reported that microRNA (miRNA) biogenesis and function are related to the molecular mechanisms of various clinical diseases. Several methods, including northern blotting and DNA chip anal-yses, are capable of assessing miRNA-production patterns in cells. How-ever, the development of repetitive monitoring of the miRNA-production profile in a noninvasive manner is demanded for the application of miRNAs to human medicine.

10p viettel02 22-02-2013 42 2   Download

The gold standard of assessing liver fibrosis is liver biopsy, which is invasive and not without risk. Therefore, searching for noninvasive serologic biomarkers for liver fibrosis is an importantly clinical issue. Methods: A total of 16 healthy volunteers and 45 patients with chronic hepatitis C virus (HCV) were enrolled (F0: n = 16, F1: n = 7, F2: n = 17, F3: n = 8 and F4: n = 13, according to the METAVIR classification). Three serum samples of each fibrotic stage were analyzed by two-dimension difference gel electrophoresis (2D-DIGE). The differential proteins were identified by...

7p toshiba23 18-11-2011 54 3   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Comparison between Flotrac-Vigileo and Bioreactance, a totally noninvasive method for cardiac output monitoring...

6p thulanh18 28-10-2011 57 3   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: "Invasive and noninvasive methods for studying pulmonary function in mice...

10p toshiba12 21-10-2011 51 6   Download