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Non-structural proteins
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Part 2 book "Dengue and dengue hemorrhagic fever" includes content: Taxonomy and evolutionary relationships of flaviviruses; molecular virology of dengue virus; the structural biology of dengue virus; the nonstructural proteins of dengue virus; the interface between dengue virus and the human host; dengue virus–mosquito interactions and molecular methods of vector control; animal models of dengue infection and disease;.... and other contents.
285p
oursky10
04-12-2023
9
2
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Newcastle disease virus (NDV) is an oncolytic virus that can inhibit cancer cell proliferation and kill cancer cells. The NDV nonstructural V protein can regulate viral replication; however, whether the V protein contributes to NDV oncolysis is unclear.
10p
vischultz
20-10-2023
4
1
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The coronavirus nonstructural protein 5 (Nsp5) is a cysteine protease required for processing the viral polyprotein and is therefore crucial for viral replication. Nsp5 from several coronaviruses have also been found to cleave host proteins, disrupting molecular pathways involved in innate immunity.
17p
vihagrid
30-01-2023
9
3
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In this article, we performed hundred nanosecond molecular dynamics simulation and molecular docking of the NS3 helicase of ZIKV with 1,4-benzothiazine derivatives. The root mean square deviation (RMSD) analyses showed the stability of the NS3 helicase.
8p
vijiraiya2711
27-05-2020
16
0
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Peste-des-petits ruminants (PPR) is an economically devastating viral disease of sheep and goats. In the present study, we have evaluated the reactivity profile of the recombinant non-structural protein C of PPR virus with vaccinated and convalescent goat sera in an indirect ELISA. The antibody against this protein is getting produced in both vaccinated as well as in convalescent animals.
6p
kethamoi4
16-04-2020
9
1
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Peste-des-petits-ruminants (PPR) is a transboundary viral disease of small ruminants. In the present study, the full length C gene was amplified from PPR vaccine virus (Sungri/96) and expressed in a prokaryotic expression system. Specificity of the recombinant C protein was confirmed through immune-blot using anti-His conjugate and hyperimmune sera from goats. The immunogenicity of the protein was assessed using monospecific sera raised in goats. The recombinant C protein produced in this study will be useful for the development of DIVA enabled vaccine and diagnostics.
6p
kethamoi4
16-04-2020
5
1
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All-oral combination of direct-acting antivirals could lead to higher sustained virologic response (SVR) in hepatitis C virus (HCV)-infected patients. In the present study, we examined the efficacy and safety of the dual oral treatment with HCV nonstructural protein (NS) 5A inhibitor daclatasvir (DCV) plus HCV NS3/4A inhibitor asunaprevir (ASV) for 24 weeks in real-world HCV genotype 1-infected Japanese individuals.
6p
viwashington2711
04-12-2019
8
0
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Classical swine fever virus nonstructural protein 5B (NS5B) encodes an RNA-dependent RNA polymerase, a key enzyme of the viral replication complex. To better under-stand the initiation of viral RNA synthesis and to establish anin vitroreplication system, a recombinant NS5B protein, lacking the C-terminal 24-amino acid hydrophobic domain, was expressed inEscherichia coli.
10p
fptmusic
12-04-2013
45
2
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Mastreviridae, of the family geminiviridae, possess a monopartite genome and are transmitted by leafhoppers. Bean yellow dwarf dirus (BeYDV) is a mastrevirus which originated from South Africa and infects dicoyledenous plants, a feature unusual for mastreviridae. Previously, the nonstructural proteins Rep and RepA were examined with respect to their independent roles in BeYDV replication.
13p
inspiron33
25-03-2013
30
4
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This study of the full-length bifunctional nonstructural protein 3 from hep-atitis C virus (HCV) has revealed that residues in the helicase domain affect the inhibition of the protease. Two residues (Q526 and H528), appar-ently located in the interface between the S2 and S4 binding pockets of the substrate binding site of the protease, were selected for modification, and three enzyme variants (Q526A, H528A and H528S) were expressed, puri-fied and characterized.
8p
media19
05-03-2013
33
3
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Since the discovery of hepatitis C virus (HCV) in 1989, there has been an explosion of research and information on the virus. This is evidenced by the more than 20 000 papers onHCV(as of December, 2000), as well as the numerous reviews in journals and edited books. The purpose of this book is to present an overview of the diVerent disciplines that have contributed to an understanding of the virus, its diseases, current and proposed treatments, and much more.
272p
gian_anh
18-10-2012
49
6
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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Respiratory syncytial virus (RSV) attachment and nonstructural proteins modify the type I interferon response associated with suppressor of cytokine signaling (SOCS) proteins and IFN-stimulated gene-15 (ISG15)
11p
dauphong7
13-01-2012
56
3
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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Tula hantavirus isolate with the full-length ORF for nonstructural protein NSs survives for more consequent passages in interferon-competent cells than the isolate having truncated NSs ORF
6p
dauphong7
13-01-2012
29
2
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Tham khảo tài liệu 'báo cáo hóa học: " rotavirus nonstructural protein 1 antagonizes innate immune response by interacting with retinoic acid inducible gene i"', luận văn - báo cáo phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả
20p
dauphong7
13-01-2012
52
4
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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Rotavirus nonstructural protein 1 antagonizes innate immune response by interacting with retinoic acid inducible gene I
20p
dauphong5
04-01-2012
35
6
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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Rotavirus nonstructural protein 1 antagonizes innate immune response by interacting with retinoic acid inducible gene I
20p
dauphong1
21-12-2011
50
4
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Human parvovirus B19 (B19) is known to induce apoptosis that has been associated with a variety of autoimmune disorders. Although we have previously reported that B19 non-structural protein (NS1) induces mitochondrial-dependent apoptosis in COS-7 cells, the precise mechanism of B19-NS1 in developing autoimmunity is still obscure.
10p
toshiba23
18-11-2011
53
2
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Tuyển tập các báo cáo nghiên cứu khoa học ngành y học tạp chí Medical Sciences dành cho các bạn sinh viên ngành y tham khảo đề tài: Parvovirus B19 Nonstructural Protein-Induced Damage of Cellular DNA and Resultant Apoptosis...
9p
thulanh9
07-10-2011
40
4
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Tuyển tập các báo cáo nghiên cứu khoa học quốc tế về bệnh thú y đề tài: Development of synthetic peptide ELISA based on nonstructural protein 2C of foot and mouth disease virus
9p
hoami_266
16-09-2011
62
5
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