Novel derivatives of murrayafoline a

Two new conjugates of murrayafoline A with zerumbone and artemisinin 3, 11 were prepared by N-alkylation, in which, compound 3 was synthesized from two consecutive Nalkylation reactions. Their cytotoxicity was evaluated on four human cancer cell lines Hep-G2, LU, RD and Fl. The result showed that both compounds exhibited no activity against the tested cell lines.

7p cumeo3000 01-08-2018 33 0   Download